In contrast, in patient aged ≥ 80 years, the OS benefit associated with maximal resection showed a favorable trend but did not reach statistical significance ( p = 0.11, Fig. 3 C).
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p=0.09
In the literature
The findings indicate that from 2010 to 2020, Jiangsu Province's agricultural eco-environment demonstrated a favorable trend, a reasonably high-quality level, and a tendency of continuous improvement from bad to good.
Nevertheless, anti-PD-1 immunotherapy plus chemoradiation is associated with a favorable trend toward improved PFS versus standard therapy in patients with locally advanced HNC.
Baseline PD1 + CD8 + T-cell levels also showed a favorable trend for PFS.
Recently, the KEYNOTE-062 could not demonstrate superiority of pembrolizumab added to chemotherapy in 1st line CPS > 1 EGA despite a favorable trend [ 22 ].
MFC-MRD–free survival showed a favorable trend in the maintenance group, although this did not reach statistical significance (2-year MFC-MRD–free survival: 85.5% [95% CI, 74.4–98.3] vs. 68.7% [95% CI, 57.3–82.4], p = 0.051).
Overall, while the findings suggest a favorable trend, the magnitude of benefit appears modest, and the clinical significance of these changes should be interpreted with caution.
However, because the post-intervention between-group comparison did not reach statistical significance, this finding should be interpreted as a favorable trend rather than definitive evidence of intervention effectiveness.
Local recurrence manifested in 20 patients (13.1%): the Kaplan–Meier survival analysis depicted in Figure 2 suggests a favorable trend in local recurrence-free survival for patients during the pandemic compared to the pre-pandemic period.
After 6 weeks, the Sleep-Extend group – who were given Fitbit fitness trackers, weekly digital content, and weekly coaching – slept ∼ 36 minutes longer and showed a favorable trend in fasting glucose levels and decreased fatigue [ 68 ].
We used different cutoffs to define bona fide targets, and enrichments were higher at more stringent cutoffs, indicating a favorable trend of our model to predict more of the genes with stronger observed down-regulation.
During the treatment period, there was a favorable trend in treatment adherence, accompanied by a low incidence of adverse events.
After the intervention, the irrational rate of emergency prescriptions decreased significantly and exhibited a favorable trend of continuous improvement.
Notably, while diarrhea and constipation showed a favorable trend in the probiotic group, the difference did not reach statistical significance, a finding also reported previously [ 49 ].
As shown in Table 4 , Aidi injection, Compound kushen injection, Delisheng injection, Huachansu injection, Javanica oil emulsion injection, Kangai injection, Kanglaite injection, Shenfu injection, Shengmai injection, Shenmai injection and Shenqifuzheng injection were 11 injections combined with NP, which demonstrated a favorable trend for relieving leukopenia compared with NP alone.
Furthermore, the integrated analysis demonstrated a favorable trend towards ceftaroline improving clinical cure rates reaching statistical significance.
as older (nonanthracycline/taxane-based) chemotherapy regimens, however the trials assessed did not have tamoxifen in both arms and indeed in the trials of LHRH agonists plus tamoxifen versus chemotherapy, the endocrine combination did not significantly decrease rate of recurrence or death, despite a favorable trend to do so.[ 25 , 28 ] Chemotherapy induced amenorrhea The indirect endocrine effect of CIA in premenopausal women with ER-positive tumors has been associated with the improved treatment outcome on retrospective analysis.[ 30 , 31 , 32 , 33 ] Rates of CIA are dependent on a number of factors, includi
22 While SGLT2i use was associated with a significantly lower risk, GLP-1RAs demonstrated a favorable trend (HR 0.86; 95% CI 0.73–1.01), narrowly missing statistical significance.
The trial demonstrated a favorable trend toward better safety profiles and neurological outcomes in the CS group, particularly regarding early post-procedural assessment [ 4 ].
Although most pairwise comparisons in the league table had 95% CrIs crossing the null, AE showed a favorable trend compared with PC (SMD = 0.36, 95% CrI 0.00–0.77) and AC (SMD = 0.45, 95% CrI 0.07–0.88).
The ASMR and ASDALYs of NRCAVD in China showed a downward trend from 2004 to 2021, indicating a favorable trend compared to the ASIR and ASPR of NRCAVD.
Although there was a favorable trend, the result of SYNTHESIS Pilot was nonsignificant when the parameter for favorable response was mRS 1 or less.
While this finding may suggest a favorable trend in renal function, it should be interpreted with caution given the retrospective design and relatively short follow-up period.
The treatment group had a favorable trend of liver enzymes after NAC initiation, with levels significantly improving by day 14 (Figures 1 and 2).
Although overall survival data remain immature, the median OS was not reached in the palbociclib arm compared with 77.0 months in the control arm (thus indicating a favorable trend that requires longer follow-up for confirmation [ 16 ]).