Nevertheless, 3 of these studies reported a favorable trend that related PIK3CA mutations with improved clinical outcomes.
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“a favorable trend”
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p=0.09
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Therefore, our results are best interpreted as showing a favorable trend rather than definitive evidence of complication reduction.
In general, 40% of patients receiving curative chemoradiation failed to return to work after treatment, but patients randomized to IMPT were more able to keep on working and demonstrated a favorable trend toward higher productivity recovery levels.
The Luo group also exhibited a favorable trend, suggesting the intervention positively enhances gut microecological function and restores core microbial composition.
Additionally, there was a favorable trend toward extended OS in the CB group ( Figure 1D ).
While OS data remain immature, a favorable trend was observed in the surgery group (HR 0.67).
The 3,200 mg dose seemed to show a favorable trend regarding change in FCP compared with placebo, but did not result in clinical remission or endoscopic improvement after 28 days of treatment.
The pooled RR was 0.72 (95% CI: 0.46-1.14), indicating a favorable trend toward the repair group, though the difference was not statistically significant (p>0.05) as shown in Figure 7 .
Treatment with elafibranor 120 mg/day showed a favorable trend toward MASH resolution without worsening fibrosis, as confirmed by liver biopsy, while also improving lipid profile, insulin sensitivity, liver enzymes, and inflammatory markers [ 135 ].
Although not statistically significant, this finding suggests a favorable trend regarding the intervention’s effectiveness.
For all-cause mortality, both DAPA-HF and the EMPEROR trials demonstrated a favorable trend, although reductions were not statistically significant in all subgroups, including non-diabetic patients [ 9 - 11 ].
The predicted aqueous solubility shows a favorable trend when Gly (−9.21) or Arg (−9.22) is added at C30 of compound 4 (−9.48).
However, animals in the experimental group treated with OPDL gel exhibited a favorable trend towards healing, even when infected with SA.
Although adjuvant HAIC (HR: 0.57; 95% CI: 0.31, 1.04) and adjuvant sintilimab (HR: 0.51; 95% CI: 0.25, 1.01) did not reach statistical significance, they still showed a favorable trend.
For multimorbid patients (at least three medical problems), there was a favorable trend without reaching statistical significance (HR = 0.77, 95% CI 0.66–0.89; p-interaction = 0.18), which means no presence of effect modification in this subgroup.
Although these differences did not achieve statistical significance for DFS or OS (P = 0.134 and P = 0.08, respectively), the pattern indicates a favorable trend associated with elevated Cyclin D1 expression.
However, the earning status of women exhibits a favorable trend, characterized by a notable rise from 2012 to 2018.
Local recurrence manifested in 20 patients (13.1%): the Kaplan–Meier survival analysis depicted in Figure 2 suggests a favorable trend in local recurrence-free survival for patients during the pandemic compared to the pre-pandemic period.
Four RCTs [ 40 , 47 , 48 , 53 ] were included in the meta-analysis, showing a favorable trend for dance but without statistical significance and with high heterogeneity (72%).
Although increases in airway volume and surface area were noted, they did not reach statistical significance ( p = 0.327 and p = 0.050, respectively), but suggesting a favorable trend toward airway adaptation.
A favorable trend was seen for patients receiving IV-rt-PA within 2 h of symptom and endovascular rescue therapy within 90 min of IV-rt-PA initiation ( 110 ).
Nevertheless, the data suggests a favorable trend using this combination therapy ( Figure 3B ).
Unfortunately, the waning on the effectiveness of administrated vaccines determined that such a favorable trend ended in July of 2021.
The authors concluded that venlafaxine showed a favorable trend in remission and response rates compared with duloxetine, but that no significant between-drug differences were observed for dropout rates and adverse events.
[ 26 ] demonstrated a statistically significant reduction in pain and opioid consumption in at least one RCT, with a favorable trend observed in two others.