Barely Significant
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a favorable trend

1,006 sentences · 1,006 papers · 2,147 search hits before verification · confirmed specimen

Sighted at

p=0.09

Listed by Hankins (2013) · Otte et al. (2022)

In the literature

The WIZARD (Weekly Intervention with Zithromax for Atherosclerosis and its Related Disorders) study failed to find a long-term benefit, even though a favorable trend was noted during and shortly after 3 months of azithromycin treatment. 12 More recent trials, ACES (Azithromycin and Coronary Events Study) 13 and PROVE IT-TIMI 22 (Pravastatin Or Atorvastatin Evaluation and Infection Therapy), 14 also reported a negative outcome.
Unpublished results ( http://10.0.82.211/rs.3.rs-2451089/v1 Peili Bu) showed that TXL led to a decrease in fibrous cap thickness increase by 27.42 μm compared with the control group, improvement in lipid core angle, reduction in severity grading of angina pectoris, and improvement in quality of life (measured by using Seattle Angina Questionnaire score), showing a favorable trend in reducing composite endpoint events (eg, all-cause death, nonfatal MI, stroke, hospitalization due to angina pectoris).
Conclusions In a real‐world national cohort of patients with HFpEF, spironolactone use reduced all‐cause death and demonstrated a favorable trend in reducing the burden of hospitalizations. heart failure with preserved ejection fraction mineralocorticoid antagonism outcomes real‐world studies spironolactone Subject Categories Heart Failure HFpEF patients in our cohort were 96% men, 85% White, and an average age of 74±11 years old at the beginning of follow‐up.
Despite a favorable trend of increased SLNB (14.9 to 54.2%) with decreased ALND (29.5 to 9.1%) over the time frame of our study, practice patterns nevertheless do not adhere to NCCN and ASCO guidelines regarding axillary evaluation, and demonstrate variation by patient ages, tumor size, geographic location, and practice facility type.
The first interim analysis, at a median follow-up of 17.9 months, showed a statistically significant improvement in PFS (24-month PFS was 67.8% with pembrolizumab + CCRT versus 57.3% with placebo + CCRT) and a favorable trend in OS (HR = 0.73) for the combination pembrolizumab and CCRT compared with placebo and CCRT, with a manageable safety profile.