Barely Significant
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“a numerical trend”

1,013 sentences · 1,013 papers · 1,817 search hits before verification · confirmed specimen

Sighted at

p=0.09

Listed by Hankins (2013) · Otte et al. (2022)

In the literature

Moreover, exploratory stage stratified analyses showed a numerical trend towards greater absolute benefit in stage II/III disease than in stage I disease (hazard ratio 0.61 for stage II/III versus 0.76 for stage I), but the test for interaction between stage (I versus II/III) and carboplatin effect was not significant (P for interaction=0.63).
For instance, the co-supplementation M + P showed a numerical trend toward mitigating the acetate reduction observed with probiotic P supplementation alone and resulted in distinct metabolic fingerprints in the distal colon, specifically altered abundance patterns of 1,603 metabolic features (m/z signals) as detected by LA-REIMS analysis, with valid OPLS-DA model differentiation (Q 2 (Y) ≥ 0.5) compared to controls.
In terms of tumor response, T-DXd showed a numerical trend toward being the top-ranked intervention (SUCRA: ORR 0.819; DCR 0.803; CBR 0.833) and demonstrated statistically significant improvements compared to TPC in both DCR (RR =0.32; 95% CI: 0.11–0.88) and CBR (RR =3.60; 95% CI: 1.06–12.60); while T-DXd also numerically outperformed SG in ORR, DCR, and CBR, these pairwise differences were not statistically significant ( Figure 6 and Table 2 ).
Taken together with the analysis of the primary endpoint in Table 3 , these results show that there is a numerical trend of continuous improvement in pain (API-NRS) from baseline to week 6 and a stabilization of the response between 6 and 8 weeks (ie, no additional improvement in pain intensity) in the LY3526318 arm, while the response to placebo shows continuous improvement.
Subgroup analyses Annualized relapse rate The significant reduction in ARR observed in the overall pooled analysis of the ITT population with ocrelizumab, relative to IFN β-1a (47% [ p < 0.001]), was maintained across the majority of subgroup-levels, including study, region, age, sex, baseline BMI, prior DMT use and prior relapse, baseline EDSS, normalized brain volume, and gadolinium-enhancing T1 lesions; a numerical trend favoring ocrelizumab was observed for the specific subgroup strata of patients aged ≥ 40 years (Fig. 1 ).
Among males, there was a numerical trend towards lower serum testosterone levels in patients harbouring a TA allele, which did not attain statistical significance ( TA/TA : 3.75 ± 2.03 vs T/TA : 4.95 ± 3.62 vs T/T : 5.65 ± 3.02; P = .339; Figure S4). 4 DISCUSSION Recently, a study linking exome sequence data from the DiscovEHR cohort 13 to electronic health records reported, that the HSD17B13 rs72613567 T > TA variant is associated with reduced risks of ALD/NAFLD as well as alcoholic and non‐alcoholic cirrhosis.
4 Overall survival (OS) analyses at SA1 revealed a numerical trend favoring D+CT versus P+CT (median 19.4 months [95% CI: 14.5–not reached] versus 15.9 months [95% CI: 11.6–19.3]; HR: 0.75 [95% CI: 0.53–1.05]; 55% maturity), 5 which was maintained at SA2 (DCO April 30, 2024; 20.2 mo [95% CI: 14.5–27.3] versus 15.9 mo [95% CI: 11.6–19.3]; HR: 0.74 [95% CI: 0.54–1.0