“a numerical trend”

These observations are consistent with those from another network meta-analysis comparing the relative efficacy of peginterferon beta-1a versus other injectable first-line DMTs, including GA, which showed a numerical trend favoring peginterferon beta-1a 125 mcg Q2W versus GA 20 mg/ml QD for 12- and 24-week CDW but not for ARR. 25 Two recent network meta-analyses also demonstrated no difference in efficacy between peginterferon beta-1a and either regimen of GA on ARR, 26 , 27 though a positive impact on risk of diseas

Although a numerical trend indicated that the ear contralateral to the lesion scored more poorly than the ear ipsilateral to the lesion did, this difference did not reach statistical significance ( Table 3 ).

Importantly, prophylactic peg-GCSF use was associated with improved patient-reported quality of life without an increase in bone pain and showed a numerical trend toward improved survival.

In contrast to the total population, when patients were stratified by cough severity, there was a numerical trend toward improvement in LCQ in patients with more severe cough versus less severe cough.

For the subset of patients where the method's assessment is in disagreement with the final IRC response, we observe a numerical trend where the OS survival rates of patients assessed as CMR by the model and non-CMR by the final IRC response are numerically better than the survival rates of non-CMR patients by the model and CMR by the final IRC response (Data Supplement, Fig S12).

However, a numerical trend for improvement was seen in the low-dose group compared to placebo. 3.4 Additional efficacy end points No statistically significant treatment effects were detected between active treatment and placebo for COWAT, CFT, CSDD, CFQ ( Supplementary Table 1 ), or the CGI-C ( Supplementary Table 2 ). 3.5 Pharmacokinetics ORM-12741 did not accumulate during the 12 weeks of treatment.

Although a numerical trend in BHB was observed, its lack of statistical significance and inconsistency with NEFA responses suggest that it does not represent a biologically relevant treatment effect.

In addition, we did demonstrate a numerical trend towards fewer MACE with an invasive approach.

Although there was a numerical trend towards larger singleton presence costs (an index of attention capture by the color singleton distractor) in the first halves of the blocks (10 ms) than the second halves of the blocks (−6 ms), F (1, 69) = 3.25, p = .08, η p 2 = .05 (see Fig. 2 B), this effect was only a small fraction of the effect reported in Vatterott and Vecera’s ( 2012 ) Experiment 1 (approximately 77 ms vs. −29 ms for the first and second halves, respectively, as estimated from their Fig. 2 ).

However, although we found that children’s comprehension in the high-relevant animation condition was significantly better than that in the low-relevant animation condition, there was no significant facilitating effect of the animation of high-relevant elements compared with the static condition (only existed a numerical trend on the test score: high-relevant is 3.32 and static is 3.03).

While no definite conclusions can be drawn based on a numerical trend, our data shows a direction of effect as was expected based on the rationale of the study analysis.

Although early ablation was not associated with improved survival or complete suppression of arrhythmic events, it achieved comparable major clinical outcomes and showed a numerical trend towards lower treatment-related morbidity and healthcare utilization.

When young and older adult participants were asked to study one aspect of a word-font pairing and were then tested on the opposing feature (e.g., studying the font and then taking a word test), a numerical trend in performance favoring older adults was observed (Naveh-Benjamin, 2000 ).

The primary and key secondary endpoints were not achieved in the overall study population or in the subpopulations evaluated in these analyses; despite a numerical trend suggesting that steroid tapering was possible to a greater extent in the ustekinumab group compared with the placebo group, there was insufficient evidence to support continuation of development of ustekinumab in patients with SLE.

While the trustworthy source was better remembered than the unspecified source for both statements with high a priori credibility, Δ G 2 (1) = 21.78, p < .01, as well as statements with low a priori credibility, Δ G 2 (1) = 14.41, p < .01, there was only a numerical trend for untrustworthy sources to be better remembered than the unspecified source, but this trend was neither significant for statements with high a priori credibility, Δ G 2 (1) = 0.79, p = .38, nor for statements with low a priori credibility, Δ G 2 (1) = 2.17, p = .14.

Regression analyses Among patients with major complication (Any CD ≥ 3), preCHT was associated with increased risk of wound rupture (OR 1.93, 95% CI 1.11–3.36, p < 0.05), and a numerical trend toward cardiovascular events.

No significant interaction was observed by device type, although a numerical trend favored Impella support in women.

They found a numerical trend in the opposite direction, i.e., the processing advantage for unpredictable words in constraining sentences compared to neutral sentences.

The difficulty ratings made by musical experts for temporal rhythms do show a numerical trend in the expected direction, with higher difficulty ratings for rhythms with more counterevidence off the beat.

In terms of treatment efficacy, the study observed a numerical trend favoring the HDVC group; however, there were no statistically significant differences in PFS and OS between the two groups.

Focusing on the interaction of stage and OS on the basis of presence of pCR, a numerical trend was noted, where studies with lower percentages of patients on stage III had stronger associations between pCR and survival.

Importantly, even though the interaction between postural control and congruency failed to reach significance by a slight margin, there was a numerical trend regarding a larger congruency effect when standing compared to sitting.

In both insulin-naïve and insulin-experienced participants, the incidence of hypoglycaemia and gastrointestinal-related AEs during iGlarLixi treatment showed no significant difference between the achieved versus the not-achieved group, although a numerical trend towards an increased incidence of both AEs was observed in participants who achieved their age-defined glycaemic target.

MAIC results were similar, also suggesting comparable rates of CR (OR 1.12; 95% CI 0.61–2.08) and CR + CRh (OR 0.83; 95% CI 0.46–1.50) between treatments; the adjusted point estimate indicated a numerical trend in favor of olutasidenib for CR and ivosidenib for CR + CRh but was not statistically significant.

Our data, based on a smaller cohort with a median follow-up of 3.5 years, showed for patients experiencing a pCR a numerical trend towards worse 3-year RFS in TNBC, cT3-4 or cN+ disease, though differences were not statistically significant.