Barely Significant
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a significant trend

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p=0.09

Listed by Hankins (2013) · Otte et al. (2022)

In the literature

a significant trendp=.204.0× alphagold
Moderated mediational models indicated no significant moderated indirect effect, however, a significant trend of indirect effect only in the BPD group was observed, whereby the no-BPD group showed a stronger direct effect (β=-0.19, t=-1.30, p=.20), whereas the BPD group showed a stronger indirect effect (β=-0.72, SE=0.45, CI= -1,71, -0.00).
a significant trendP = 0.2054.1× alphagold
Cumulative meta-analysis did not show a significant trend for overall complications by study era ( P = 0.205), and for studies that reported use of a single biopsy needle size for procedures, there was no significant difference in the overall complication rate between 16G and 18G needles ( P = 0.334) ( Supplementary Figures S1 and S2 ).
a significant trendp = 0.244.8× alphagold
Subgroup analysis showed significantly higher HR from retrospective studies (HR: 1.89, 95% CI: 1.09–3.29, z = 2.27, p = 0.02, τ 2 = 0.20, I2 = 44.71%), while such a significant trend was not confirmed pooling results from RCTs (HR: 1.70, 95% CI: 0.70–4.08, z = 1.18, p = 0.24, τ 2 = 0.61, I2 = 63.91%), among which a significant heterogeneity occurred ( Supplementary Materials—Figure S12 ).
a significant trendp = 0.2414.8× alphagold
On the contrary, Figure 3 B shows that natural killer lymphocytes ( p = 0.131), natural killer lymphocyte granzyme + ( p = 0.521), T cytotoxic lymphocyte granzyme + ( p = 0.760), T natural killer lymphocytes ( p = 0.131), total plasma cells ( p = 0.822) and Ab-secreting plasma cells ( p = 0.497) did not have a significant trend among the four groups, nor did the number of days to negative nasopharyngeal swab ( p = 0.241).
a significant trendp = 0.275.4× alphagold
Those carrying both Bw4Ile80 and KIR3DS1 did not display a significant trend towards higher CD4+ T cell counts over the period of observation (+ 40 cells/uL [SE = 36.5], p = 0.27, Figure 1 C), and displayed a trend towards a reduction in viral loads (−0.22 log 10 [SE = 0.15] lower HIV-1 RNA copies/mL, p = 0.14, Figure 1 C) relative to those who did not carry both genes.