“a slight trend”

We found that placing an edit at the cut site and on the PAM-proximal side both allowed successful editing, with a slight trend favoring the central cut.

However, there was a slight trend toward a marginally better health status in SD than HD recipients: The percentages of recipients having or having experienced medical conditions within the last 5 years were slightly higher in the HD than in the SD cohort as were the percentages of recipients who died or were admitted to a nursing home during the study.

Additionally, there was a slight trend toward an increased RER in the Adipoq‐F2‐KO mice, particularly during the light/resting period, where the RER approached 1.0, suggesting a preference for carbohydrate metabolism over fat (Figure 4g ).

Our results indicated that an extension of the invitation interval has no significant impact on the stage distribution for both screen‐detected and interval cancers, although there was a slight trend towards a higher percentage of late‐stage cancers in groups with extended intervals.

Overall, there was a slight trend for δ 15 N to increase 0.06 for every increase in one nestling fledged from each nest.

In our comparison of overseas versus local endoscopists in the live course setting, we did observe a slight trend toward higher adverse events in the overseas endoscopist group.

Across most of the reported actions, mentors and mentee assessments of frequency did not statistically differ at the population level, but there was a slight trend for mentees reporting lower frequency of behaviors than what mentors self-reported.

At the pre-attachment step, EA at CC 20 and CC 50 showed a slight trend towards inhibiting HPV16 pseudovirus, but this was not significant.

Wine consumption was associated with a significant reduction of the risk of type 2 diabetes, with the pooled RR of 0.85, whereas beer or spirits consumption led to a slight trend of decreasing risk of type 2 diabetes (relative risk 0.96, 0.95, respectively).

Compared to the significant decrease in ST3GAL2 expression at the mRNA level and the apparent decrease in immunofluorescence signal of the ST3GAL2 protein, we found only a slight trend towards down-regulation of ST3GAL2 at the protein level by Western blot in infected samples (not significant; Fig. 4 C).

Here, a slight trend for hemolytic anemia in T2D patients was too mild to emerge from routine hospital analyses based on indirect biomarkers of hemolysis (AST, iron, bilirubin and LDH), known to be impacted by the many metabolic modifications that prevail in T2D.

There was a slight trend towards a lower performance as the width of the Gaussian kernels was increased, which means that as the weight assigned to positions further away from the central amino acid increases, the performance tends to degrade slightly.

There was a slight trend for increased dye accumulation with reduced amount of dysferlin protein among the 40aKO mice (Fig. 4 b).

There is a slight trend for the model to underpredict the decline for subjects ≥7 years old at baseline, but the predicted mean data are maintained within the SD of the observed data ( Table 3 ).

Additional NAFLD-specific phenotypes, such as inflammation and hepatocellular ballooning 31 , did not differ significantly between treatment groups in the samples analyzed, although there was a slight trend toward improved inflammation scores in the WD/LD-T group relative to the WD/WD-V group (Supplementary Table S2 ).

The addition of Dex in different concentrations (0, 10^1, 10^2, 10^3 nM) to C57BL/6 mice OBLs did not significantly influence the bone nodule forming capacity of these cells, however a slight trend of dose response could be observed (higher doses of Dex seemed to induce more calcium deposition) ( Fig. 5a,b ).

In the MRD trial, the time to reach peak plasma cGMP concentration was approximately 1 h after BI 685509 administration; although there was a slight trend toward higher mean cGMP levels at higher BI 685509 doses, there was no definitive evidence of a dose-dependent effect.

The initial PCA, which was performed using the 31 samples analyzed, showed a slight trend of grouping according to infected and non-infected samples by means of PC1, although with some sample overlapping.

There was a slight trend of decreases in bet size after a series of wins, but this was not significant.

Moreover, we observed a slight trend of improved estimates from the TOA scale, in particular for crop traits at the canopy level (i.e., LAI and laiCw).

While no distinct overall pattern was observed, a slight trend emerged, suggesting that glycolysis and fermentation pathways were more abundant in 12-year-old samples, whereas the TCA cycle was more prominent in 4-year-old trees, as shown in Figure 4 .

We could not reproduce these results in our pediatric population, besides a slight trend toward increased IFNγ production by iNKT cells during crisis.

There was a slight trend with the creatine only group towards improvement in time to VO 2peak , but this was not statistically significant.

The data indicated a rise in depressive symptom scores in the late menopausal transition stage with a slight trend toward lower CESD scores in the early postmenopause compared with the late reproductive stage.

No significant difference was observed in OS (HR: 0.78 [0.55, 1.12], P = 0.18), although a slight trend favoring PIC therapy was noted.