However, there is a slight trend towards smaller side chains at positions contributing to the central hydrophobic core of the funnelin domain, which might lower thermal stability: Leu78Ala, Tyr96Leu, Ile97Val, Ile80Ala, Met100Ile, Leu111Val, Leu119Ala, Leu128Val, Met143Cys, and Ser151Ala.
Despite a slight trend towards decreased motor performance, nes-CrT –/y mutant mice did not differ from CrT +/y and nes-CrT +/y mice in the rotarod task, with a similar fall latency at all ages tested (Fig.
The correlation graphs of the Figures 4 , 5 , and 6 show a slight trend towards better results with EPIDose TM than MapCHECK TM dosimetry, i.e., lower mean γ values, higher percentage of points with γ < 1 and similar trend for percentage of points with γ < 1.5.
The plot shows a slight trend in the differences between overground and treadmill cadence.
The GMR of 0.96 is close to 1, indicating near proportionality with a slight trend toward sub‐proportionality.
However, there is a slight trend of correlation decreasing as the number of walks increasing.
While there was a slight trend toward fewer ticks making a choice with increasing concentration of DEET exposure, this was not the case with picaridin or 2-undecanone.
Additional NAFLD-specific phenotypes, such as inflammation and hepatocellular ballooning 31 , did not differ significantly between treatment groups in the samples analyzed, although there was a slight trend toward improved inflammation scores in the WD/LD-T group relative to the WD/WD-V group (Supplementary Table S2 ).
The addition of Dex in different concentrations (0, 10^1, 10^2, 10^3 nM) to C57BL/6 mice OBLs did not significantly influence the bone nodule forming capacity of these cells, however a slight trend of dose response could be observed (higher doses of Dex seemed to induce more calcium deposition) ( Fig. 5a,b ).
In general, a significant part of the subsequent data of this scenario remained within the acceptance range, with a slight trend of underestimation.
From a recent compilation of safety profiles for different types of carrageenans in subclinical assays with different cells and in clinical studies [ 32 ], half maximum cytotoxicity concentrations were in the range 5–3000 μg/mL with a slight trend showing lower toxicity for the more sulfated carrageenans.
While the quantified concentration of indigoidine via a colorimetric assay did not show a strong dependence on initial concentration of sugar present in the cultures grown in glycerol, a slight trend towards more intense coloration of the culture with increasing sugar concentration was observed (Fig. 3 a).
Finally, the counts of lymphocytes and white blood cells showed a slight trend to diminution, but the final effect with this limited number of subjects did not reach statistical significance ( Fig 4C ).
For representatives of Solobacterium (P = 0.054) and Fusobacterium (P = 0.065) a slight trend towards reduced abundance in samples derived from GC treated patients was observable, but is missing significance.
The secondary outcomes of the study were not impacted by the additional operations performed ( Figure 4 ) but showed a slight trend toward the indications ( Figure 5 ).
There was a slight trend of decreases in bet size after a series of wins, but this was not significant.
However, there was a slight trend in higher IL-10 translational activity in LD patients.
A slight trend of nonlinearity was observed at doses ≤1.0 mg/kg, possibly due to target-mediated clearance at lower etrolizumab serum concentrations.
However, there was a slight trend suggesting that TSH levels might increase with higher exposure, which was close to being statistically significant ( p -trend = 0.05) [ 19 ]. 3.1.2.
While no distinct overall pattern was observed, a slight trend emerged, suggesting that glycolysis and fermentation pathways were more abundant in 12-year-old samples, whereas the TCA cycle was more prominent in 4-year-old trees, as shown in Figure 4 .
A slight trend increase in malaria incidence in 2020 could be a blip or a true increase as a result of the Covid-19 pandemic that might have negatively impacted malaria control programs such as clinical care provision and bed net distribution [ 6 ].
In addition, a slight trend towards decreased IgG titers and neutralization capacity in Viperin −/− animals was observed in the non–CD4-depleted mice ( Fig 1B and D ).
Our study suggests that the ability to generate an adequate immune response is vital for the disease course of COVID-19, as our data revealed that while not statistically significant, there did appear to be a slight trend toward worse outcomes for patients who received lympho-depleting chemotherapy within 30 days of their diagnosis versus patients who did not receive lympho-depleting chemotherapy within 30 days of their diagnosis.
Results There was a significant difference in RPE between weeks ( p = 0.015, W = 0.19) with a slight trend in decreasing RPE.
There was a slight trend with the creatine only group towards improvement in time to VO 2peak , but this was not statistically significant.