There was a strong trend to a decrease in epigenetic age acceleration in female participants with the novel InflammAge clock ( p = 0.05, Suppl.
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p=0.077
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While the serum IL-18 levels were similar in the hypertensive compared with the normotensive group, normotensive men had a strong trend of increased IL-18 levels compared with corresponding women ( P =0.05; Figure S7C ).
In the data analyzed here, we did not observe any marked differences in effects when adding meditation status ( n = 6) as a covariate, but the shift in the NREM gamma band from a strong trend (uncorrected p = .05) to a significant effect in the regression analysis corrected for meditation status ( p .=011) indicated that meditation practice might indeed mask the strength of the effect in the NREM-gamma band.
In the Italian comparative study of standard versus more aggressive surgery [ 15 ], the addition of RT, administered preoperatively or postoperatively, seemed to result in LR reduction ( p = 0.023) and a strong trend towards increased OS ( p = 0.050).
In probe trials 1 and 2, performed at the end of hidden trial days 1 and 2, only sham mice for each of the genotypes showed preference for the target quadrant; a strong trend ( p = 0.0501) was observed in probe trial 2 for brain-injured syk f/f MRP8-cre + mice ( Supplemental Fig. 7B , C ).
0.22 CE; P = 0.029) and a strong trend for overall T cell breadth (1.14 vs. 0.52 CE; P = 0.051).
There was also a strong trend for thicker scar tissue in the Tisseel group (P=0.051), without the anastomotic site containing more fibroblasts (P=0.126) or collagen (P=0.097).
In line with most other AS and CA studies, 20 , 21 , 25 we observed a strong trend towards a more impaired renal function at baseline in patients with concomitant CA ( P = 0.051), which might contribute to the higher incidence of post‐procedural AKI in these patients.
For the right hippocampal body, the ANCOVA showed a strong trend ( p = 0.051); therefore, we performed the post-hoc tests, which indicated a significantly smaller volume in L+ patients when compared to L– patients and a trend when compared to the control group ( Table 3 ).
Both doses of MLM55-38 stimulated locomotion relative to vehicle ( p -values ≤ 0.003) and SKF was more efficacious than 5 mg/kg MLM55-38 ( p = 0.003) with a strong trend relative to the 10 mg/kg dose ( p = 0.051) ( Supplementary Table S2 ).
Finally, pediatric patients with secondary PAD had a strong trend toward a lower mean anti-spike antibody response after two-dose vaccine series compared to primary PAD patients (767.1 vs. 3,679.2 U/mL; p=0.051) ( Figure 2 ).
Additionally, we found mediating effects of C-C motif chemokine ligand 13 (CCL13) and endothelial monocyte-activating polypeptide II (EMAP-II) between OSA and HBP with the IVW-RE method; however, in the cML-MA-BIC method, the negative association between OSA and EMAP-II only showed a strong trend of statistical significance ( P = 0.0510), and the negative association between OSA and CCL13 approached statistical significance ( P = 0.0668).
In the subset MSSOpoly, differences, most of which were not statistically significant, could be obtained in onset symptoms and symptoms at the last visit, with a strong trend of a higher rate of walking impairments in MSSOpoly (68%) compared to MSS- (50%, p = 0.051). 58% of MSSOpoly were working at the last reported visit compared to 67% in MSS- ( p = 0.4).
There was a strong trend toward a positive association between SDF1a and the risk of DN [OR IVW : 1.26, 0.99–1.59; p = 0.051].
However, there was a significant choice × emotional content interaction, F (1, 16) = 6.33, p = .023, ŋp2= .284, and a strong trend towards a choice × emotional content × feedback interaction, F (1, 16) = 4.44, p = .051, ŋp2 = .217.
In the second model of multivariable analysis, taking into account the use vs not-use of medical devices, a strong trend supporting a protective role for diabetes nearly reaching statistical significance was observed (OR 0.64, 95% C.I. 0.41–1.00, p = 0.051).
Semi-automated analysis of the acquired images revealed a decrease in the percent of mitochondria colocalized with LAMP1 in SH-Spike compared to SH-EV cells, with a strong trend in the Manders’ colocalization coefficient (p = 0.0516, Fig. 5 e).
Accordingly, our previously identified T2D-induced hsa-let-7e-5p ( Krause et al., 2020 ) shows under this stratification only a strong trend (p=0.0518) to be elevated in T2D.
Whereas we did not observe a significant difference in PFS [CHT: 3.0 months (95% CI 1.4-4.6 months) versus nCHT: 3.2 months (95% CI 2.8-3.6 months), P = 0.725], there was a strong trend towards longer OS in the CHT group [CHT: 15.5 months (95% CI 8.0-23.0 months) versus nCHT: 5.3 months (95% CI 0-12.5 months), P = 0.052] ( Figure 1 C).
In addition, PFI was 32.7 months (95% CI 13.8-NA) in the all genetic mutation group, and 15.9 months (95% CI 8.3-34.1) in the HRP group, showing a strong trend toward statistical difference (p= 0.052).
In HPMEC cell line A, there was a strong trend toward greater permeability with living donors at S3 that just missed significance ( p = 0.052).
We found a significantly higher rate of immediate progression in rectal NEC with ARID1A deletions (56 vs 33%, OR 6.43, 95%CI 1.05–39.33, p = 0.044) and a strong trend towards inferior RR (OR 0.19, 95%CI 0.03–1.02, p = 0.052).
Among the 4 groups, AGT exhibited no statistically significant differences; however, it did indicate a strong trend ( P = 0.052) that did not reach statistical significance.
Following the switch to HFD on D10, HFD-V animals consumed the most calories (Tukey’s HSD, p < 0.05) except on D31, when food intake for HFD-V showed a strong trend towards an increase compared to HFD-E (p = 0.052) and D34 (Fig. 1 B).
In addition, we observed a strong trend for a higher occurrence of nausea (52.9% vs. 27.9%; P = .052) and obstipation (5.9% vs. 0.0%; P = .057) in patients with prior antibiotic use.