In turn, a significantly higher risk of non-response after the 4th cycle of chemotherapy was observed in patients with elevated CRP (OR = 6.70), those with the presence of t(11.14)/CCND1 translocation (a trend toward significance; OR = 6.42) and those who were carriers of the TT genotype of the KIAA1524 gene (OR = 20.20).
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“a trend toward significance”
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The marginal p values ( p =0.054) for age reflect a trend toward significance, likely due to older adults facing fewer stigma-related barriers.
Higher IHS4 scores at the end of follow-up (OR 1.06; 95% CI 1.00–1.12; p = 0.065) and lack of preoperative ultrasound evaluation (OR 2.48; 95% CI 0.89–6.89; p = 0.081) showed a trend toward significance.
Similarly, although we observed a trend toward significance in facelike object responses, it was no longer significant following FDR correction for multiple comparisons (mean difference = 3.47 μV, 95% CI = [0.54, 6.57], uncorrected p = .044, FDR corrected p = .12).
However, none of the predictors found for studies with at least one toxic fatal event proved to be independently correlated with TRD at multivariable analysis, with only a trend toward significance for oral cavity subsite (renal failure was excluded for low numbers of studies; Table 4 ).
Remission rate showed a trend toward significance at day 7.
The association between playing sports at 10 years and having fewer mental health problems measured at 10 years showed a trend toward significance (> 4 hours/week: β = − 0.28, 95% CI = − 0.53; − 0.03, P adj = 0.099).
While NLR quartiles showed a trend toward significance in the unadjusted model (p for trend < 0.05), no significant associations emerged when NLR was analyzed as a continuous variable in unadjusted or adjusted models.
13 The factors male gender, using fewer tools to prevent forgetting, and patients' having an indifferent attitude toward medicines showed a trend toward significance in multivariate analysis.
Chronic or gradual noncontact injuries (n = 758) had the shortest RTP at 14.9 days ( P = .0648), demonstrating a trend toward significance.
The relationship between acupuncture treatment and the risk of AMI among stroke patients existed for both sexes and for patients aged 50–69 years; however, there was a trend toward significance in the following age categories: 40–49 and 70–79 years.
The current study also did not find a difference in the duration of opioid use or MMEs prescribed although, with the larger numbers in this study, there was a trend toward significance in the subset of patients who underwent TKA.
Patients with an ML tear size <62% had a hazard ratio (HR) of 1.78 (95% CI, 1.04-3.04), while those with tendinosis grade 2 had an HR of 3.51 (95% CI, 1.86-6.61), and tendinosis grade 3 had an HR of 2.23 (95% CI, 0.96-5.19), showing a trend toward significance.
A P -value ≤ 0.05 was considered significant; a P -value > 0.05 and ≤0.10 was considered a trend toward significance.
Notably, there was a trend toward significance in a reduction of GluA2 levels ( Fig. 9 K), and a significant reduction in GluN1 levels, both in stressed males compared to sex-matched controls (Fig. 9L).
No statistically significant difference was found in satisfaction with or understanding of why the medication switch was made when assessed by sex, age, race, or education, but there was a trend toward significance in the distribution of answers based on education level with those with a high school diploma, General Educational Development (GED) or less being more likely to be satisfied with the medication switch ( p = 0.074).
There was only a trend toward significance for a higher level of pain during chest tube removal in the ICNB (3.06 ± 1.21 vs. 2.35 ± 1.34, p:0.072), Table 3 .
In contrast, for trochanteric fractures, postoperative myocardial infarction, and cognitive dysfunction showed a trend toward significance but did not meet the predefined threshold for statistical significance.
A p-value of less than 0.05 was considered statistically significant, and a p-value of less than 0.1 was considered a trend toward significance.
A shorter time to initiation of systemic therapy ( p = 0.023) was associated with a higher likelihood of dose optimization, while a lower BMI ( p = 0.099) showed a trend toward significance.
We then analyzed each of the variables, AID mRNA, AID IHC and BG4 IHC, independently and observed only high AID mRNA levels identified DLBCL patients with worse OS and PFS, which maintained a trend toward significance with DLBCL subtype as a covariate for PFS only (Figure 6A ).
A P -value <0.05 was considered significant, and P -values 0.05–0.10 were considered to indicate a trend toward significance.
22 Each independent variable whose likelihood ratio test showed a trend toward significance was included in the final model.
Although postoperative AKI (OR = 1.43, 95% CI 0.98–2.08, p = 0.06) showed a trend toward significance, it did not reach statistical significance in the multivariate model.
However, only one electrode showed a trend toward significance, with a SPEX coefficient increase in the Drug Post condition, a direction that would indicate a E/I balance shift toward inhibition.