“an increasing trend”

The prevalence of subclinical hypothyroidism exhibited an increasing trend as UIC and UI/Cr levels increased (UIC: χ 2 = 40.470, p < 0.001; UI/Cr: χ 2 = 161.513, p < 0.001).

The variables “family history of cancer” (p<0.001), “alcoholism” (p<0.001), “smoking” (p<0.001), “TNM staging” (p<0.001) had a decreasing trend, while “clinical start of treatment” (p<0.001), “origin” (p=0.008) and “occupation” (p<0.001) indicated an increasing trend.

Subgroup analysis for PROs At W52, the mean DLQI score showed an increasing trend with the increase in times of treatment interruption ( P <0.001), and achievement rates for DLQI 0/1 showed a decreasing trend ( P =0.007).

Inflammatory markers measurement As seen in Figure 6 , the production of IL-6 and TNF-α in ethanol treatment group had an increasing trend as compared with the control group in the liver ( P< 0.001 and P< 0.05, respectively).

Specifically, during the period from 1990 to 1999, ASMRs for male demonstrated an increasing trend, with an AAPC of 0.30 (95% CI 0.19 to 0.41; p < 0.001), whereas ASMRs for female indicated a decreasing trend with an AAPC of −0.17 (95% CI −0.43 to 0.08).

The estimates of the number of HIV tests per month had an increasing trend over the time after March 2020, with a slope of 98.29 (β 2 = 98.29; P < .001).

An increasing trend with IgG was observed along with the age groups [6-15 yr (36%), 16-25 yr (45%) and >25 yr (69%), P <0.001], and it was maximum in village Hamimpur (68%) followed by Belakata (65%), Kazipur (51%), Rajhi (39%) and Vikas Nagar (34%), ( P <0.001).

80.17%) both showed an increasing trend (χ 2 = 241.725, P < 0.001 vs. χ 2 = 190.382, P < 0.001), as illustrated in Fig. 1 C and D.

Results From 2001 to 2020, there was a significantly decreasing trend in the proportion of hospitalizations for SCZ ( p < 0.001) and an increasing trend for depression and CED ( p < 0.001).

In addition, there was an increasing trend in number of tests ordered in the past year among pediatric ( P < 0.001, Supplementary Table S1 ) compared with adult clinicians .

In parallel, we found a decreasing trend in DIN loads (− 0.70% annually, p < 0.001) and an increasing trend in TON loads (2.11% annually, p < 0.001) in the five studied Norwegian rivers over the past 27 years (1990–2017) (Table 1 , 2 ) (Fig. 2 c,d).

There is no clear pattern of increase in UV Index in Sweden, England, and Australia ( p > 0.05); however, there was an increasing trend of UV index in the USA (β = 0.047; p < 0.001).

Age-standardized mortality rates across most high-income countries exhibited an increasing trend (average APCs ranging from 1.1%/y [ P < 0.001] in the United Kingdom to 2.4%/y [ P < 0.001] in Italy), while Japan demonstrated a decreasing trend (average APC −2.1%/y, P < 0.001), and the United States demonstrated a constant trend (average APC −0.5%/y, P = 0.14) ( Table 1 , Central Illustration ).

Group A was defined as the group of patients who had a mild level of fatigue at baseline, with their fatigue level demonstrating an increasing trend during the treatment period but consistently remaining at a mild level ( I = 1.111, P < 0.001; S = 0.439, P < 0.001).

The GnRH levels from NP-treated hypothalamus showed an increasing trend, especially significant in male 10 nM- and 100 nM-treated groups ( p <0.001) and female 1 nM-, 100 nM- and 1 μM-trated groups ( p <0.05, p <0.01 and p <0.05, respectively).

In a fully adjusted model, using the 36th month scores as reference, there is an increasing trend between the supplement users and non-users for the MMSE (estimate: −1.22; 95% CI: −1.78,0.67) (p<0.001), digit span (estimate: −1.11 (95% CI: −1.56,-0.66)) (p<0.001) and VRI scores (estimate value of −10.47 (95% CI: −15.41, −5.17)) (p<0.001).

There was an increasing number of cases published in the literature over time: the first cases were described in 1979, followed by 3 cases in the 1980s, 2 cases in the 1990s, 2 cases in the 2000s, and 48 cases from 2010 to the first quarter of 2016, demonstrating an increasing trend of aspergillosis superinfection ( P < .001).

There was an increasing trend in mean length of hospital stay (coefficient estimate 0.2 d per year; P < 0.001) (Figure 1D ) and hospitalization cost (coefficient estimate 5778 United States dollars per year; P < 0.001) (Figure 1E ) among hospitalization for HRS during 10-year period from 2005 to 2014.

Both these scores showed an increasing trend with respect to the academic year ( P < 0.001).

Figure 1 illustrates an increasing trend for depression, anxiety disorders, and insomnia percentages among participants with a rising fear of COVID-19 (P < 0.001).

With the increase of CMI levels, the risk of CMD showed an increasing trend, p < 0.001.

Comorbidity Phenotype Trends Comorbidity phenotype trends were directionally consistent with the NE–PSY divergence: cerebrovascular and motor deficit phenotypes showed an increasing trend ( p < 0.001), neurodegenerative increased ( p = 0.001), psychiatric primary decreased ( p = 0.014), and behavioral showed no statistically significant variation ( p = 0.82) ( Figure 6 ). 3.5.2.

Parenchymal contrast also demonstrated an increasing trend with decreasing keV values in PCD-CT on both phases ( P < 0.001 to 0.004 for AP and P < 0.001 to 0.001 for PVP).

There was an increasing trend in HI in accordance with the severity of emphysema (Jonckheere–Terpstra test, P < 0.001).

As shown in Table 3 , an increasing trend in the H-TEAC of R. rugosa hips was observed with significant differences ( p < 0.001) between the different maturity stages.