“an increasing trend”

Over the longer-term period of 2000–2020, there is an increasing trend in flooded area (with an MK test of P < 0. 01), based on the JRC Global Surface Water dataset (Fig. 3 c).

coli , Enterobacter species and Serratia species had a steady isolation rate over the ten year period, while Klebsiella species showed an increasing trend in their isolation rate, from 22.6 to 50.9% (χ 2 = 29.1, P < 0.01) of the total Gram-negative bacterial group (excluding Salmonella species).

Expression of OCN also showed an increasing trend ( p < 0.01).

In the three CRC groups, the levels of these five urinary proteins showed a gradient with an increasing trend that correlated with disease progression, achieving the highest levels in DM ( P < 0.01 for all; Fig. 4a ).

A decreasing trend was observed for keratoleukoma ( P < 0.01) and an increasing trend for corneal endothelial dysfunction ( P < 0.01), regraft ( P = 0.012), corneal limbal dermoids ( P < 0.01) and congenital corneal opacity ( P < 0.01).

However, following treatment with LTP and AP, the concentrations of ZO-1 and occludin in renal tissues showed an increasing trend ( P < 0.01) (Figure 3A and B ).

Results 76,873 patients were diagnosed with GBC with decreasing incidence rates in all races/ethnicities except NHB who experienced an increasing trend between 2001 and 2014 (APC = 2.08, p < 0.01) and plateauing afterward (APC = −1.21, p = 0.31); (AAPC = 1.03, p = 0.03).

Throughout the aging process, the SP content of oat seeds exhibited an increasing trend, with highly significant differences observed in the SP content of the two varieties ( P < 0.01).

In HC and Mod/Sev, but not the MA subjects, stimulation of PBECs with EGF enhanced the chemotactic activity when compared to basal-CM (p = 0.021 in HC, 0.093 in MA and 0.010 in Mod/Sev asthma, Table S1); the EGF-CM activity was related to clinical asthma severity as shown by an increasing trend (linear contrast test p = 0.010) ( Figure 2A ).

The proportion of total outpatient visits of member public hospital has shown an increasing trend by 0.063% before the reform ( p < 0.01), and decreased by 0.089% per month ( p < 0.05) after the reform, while the change of member private hospital showed no significant change.

Although HPV52 showed an increasing trend (Z = 2.797, p < .01), no discernible upward or downward trend was observed for total high-risk HPV (Z = 0.637, p > .05).

Before the guideline introduction, there was an increasing trend in 6-month BP follow-up (316 of 2400 patients [13.2%] to 746 of 3466 patients [21.5%]; β = 0.116; 95% CI, 0.029 to 0.203; P = .01) and 1-year BP follow-up (657 of 2400 patients [27.4%] to 1227 of 3466 patients [35.4%]; β = 0.134; 95% CI, 0.047 to 0.221; P = .003).

Despite these initial differences, all groups demonstrated an increasing trend in life satisfaction over time (p < .01).

It was also found to have an increasing trend of association with sleep frequency (Jonckheere-Terpstra test: JT = 832, p value < 0.01), and have a decreasing trend with anger frequency (Jonckheere-Terpstra test: JT = 475.5, p value = 0.01) (Fig. 2 f–g).

Despite these initial differences, all groups demonstrated an increasing trend in life satisfaction over time (p < .01).

A downward trend was observed in the proportion of pneumonia patients with COPD during the last decade ( P < 0.01), while an increasing trend was observed in the proportion of patients with lung malignancy ( P = 0.01) or bronchiectasis (P < 0.01) (Fig. 3 - A).

After the implementation of the NVBP policy, the continuously increasing trend of the average monthly per-visit expenditure of chemotherapy drugs ( p < 0.01), oral endocrine drugs ( p < 0.01) and TCM ( p < 0.01) has been effectively mitigated; in particular, the average monthly per-visit expenditure of TCM has been changed from an increasing trend to a decreasing trend with 12.22 CNY ( p < 0.01) per month.

The LCIV showed an increasing trend in the DTLK group from T12-L1 to L4-L5, with significant intra-group differences ( p < 0.01) ( Table 2 ).

Over time, VEGF expression in the Model, US, and USMB groups exhibited an increasing trend, with the USMB group reaching the peak level on day 8, which was significantly higher than both the Model and US groups ( p < 0.01).

3.4 Trends over time While few papers report the evolution of incidence rates during the study period, all of them report an increasing trend for SM or MESCC: Sohn reports a rising annual incidence from 6.04 to 6.94 per 100.000 population (p=0.01) [25] for SM.

The first cases appeared in 2018 (0.01/1000 patient-days), increasing to 0.10–0.16/1000 patient-days in subsequent years—an increasing trend in 2018–2024 (average +0.02/1000 patient-days per year; p = 0.01).

The ASR of YLD and DALY showed an increasing trend from 1990 to 2021 ( P < 0.01), but the ASR of mortality and YLL showed a decreasing trend ( P < 0.01).

In contrast, the H7N7 infected control animals showed an increasing trend of weight loss that was significant compared to the vaccinated H7N7 infected mice on day 7 ( p = 0.01) and day 8 ( p = 0.0003) post H7N7 infection ( Figure 1E ).

T-cell ALL only showed an increasing trend for young adolescents (15–17 years) from two patients per year on average in the 1990s to four in 2010–15 (AAPC + 3.7%, p = 0.01) (Supplementary Table S1 ).

Time Trends and Subgroups of CHD The overall incidence of CHD increased from 10.29‰ (2206/214333) in 2018 to 13.45‰ (2,174/161,605) in 2020, revealing an increasing trend of 30.7% [overall: χ 2 = 50.13, P < 0.01; 2018 vs. 2019: χ 2 = 4.94, P < 0.05); 2019 vs. 2020: χ 2 = 23.24, P < 0.01; 2018 vs. 2020 (χ 2 = 47.75, P < 0.01)].