Reciprocity was small and non-significant in period-1 (estimate= 0.09) but increased in period-2 (interaction estimate = 0.44), approaching significance, suggesting a possible strengthening of reciprocal friendships over time, though the effect did not reach conventional significance.
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Other sentinel CpG sites were also approaching significance for interaction after adjustment for multiple testing (see Additional file 2 ) and in all cases Europeans showed larger effect sizes when comparing never and current smokers (See Table 3 ).
Genes were observed approaching significance with FDR of 0.10 and fold changes (ratios) −2.0 or less and 2.0 or more.
The biosynthetic enzymes TRI1 , TRI5 , TRI13 and TRI101 were significantly down-regulated, while TRI4 was down-regulated, only approaching significance.
Statistical significance is reported at level α = 0.05; associations in the multivariate models with p -values less than α = 0.1 are noted as approaching significance to avoid overlooking associations that were not significant because of limited sample size.
The MEGA-analysis identified two signals, one meeting a genome-wide significance threshold and the other approaching significance.
In view of this, finding the underadditive interaction approaching significance in the not-remove condition of Experiment 2 is not very remarkable.
Longitudinaly ( N = 43), permutation testing revealed that converters and non-converters showed significantly different local shape alterations over two years in the brainstem ( P FWE max = 0.045), and clusters approaching significance in the left thalamus ( P FWE max = 0.06) and left amygdala ( P FWE max = 0.083).
The average r-value was 0.4903 using Landsat-8 information and no significant differences were found; however, the p -value was 0.0751, that is, approaching significance.
While we did not observe statistically significant differences in these markers, we did note trends towards increased expression in GH-treated animals for all markers, approaching significance for erbB3 and p75 expression.
Childhood environment exhibited a significant positive correlation with perceived health at ages 63 and 73 and was correlated with perceived health at age 78 at a level approaching significance.
In the present study, our IC birds probably had less glycogen content at slaughter and therefore had a final muscle pH 24h that was approaching significance and significantly higher shear force values.
While the constant (B=66.599,p<.001B = 66.599, p <.001B=66.599,p<.001) is significant, the predictors show minimal influence, with “Compassionate Care” approaching significance but not reaching it. 5 Discussion The discussion section of this study provides critical insights into the complex relationship between empathy and assertiveness among undergraduate medical students, emphasizing the need for a nuanced understanding of these interpersonal skills.
In the present study a priori comparisons between cannabis + tobacco and cannabis alone were only approaching significance for d ′.
Although the findings that the utilisation of survivorship support services by individuals higher in personal control, problem-focused coping and emotion-focused coping were significant or approaching significance, these variables did not explain a high percentage of variance in supportive care use.
The same held true for cells derived from IHMCs treated with either IL-2 or IL-12 alone, although FasL blocking had an effect approaching significance.
We observed significant time-of-day variation for p-tau217, NfL, Aβ40, Aβ42, and Aβ42/Aβ40 with the effect approaching significance for GFAP, with the magnitude of diurnal variation ranging from 4.6% to 15.8% for the significant effects.
The P -value for statistical significance was set at P ≤ 0.05, unless otherwise noted P ≤ 0.10 was considered as a tendency approaching significance.
Both studies showed statistically significant individual improvements in anxiety symptoms, with the overall effect approaching significance.
Similar trends were noted for patients with isolated other/unspecified VHD history, although reaching significance only for total (first and recurrent) HHF (HR, 2.54; 95% CI, 1.30-4.95; P < .01) and approaching significance for time to CV death.
Of the five predictor variables, Verrucomicrobia was statistically significant while FACT-Cog and CES-D were approaching significance.
What we found is that, though those already on antibiotics started with, albeit non-statistically, lower SOFA scores (approaching significance on ICU day #3), in no other regard was their outcome statistically superior.
Although no significant GWA signals surpassed the Bonferroni threshold in 2022, an emerging signal on chromosome 3B, similar to those observed in 2020, 2021, and the combined analysis, was observed, with the top SNP approaching significance (Figs.
Looking at sites reaching or approaching significance ( q < 0.20), we find many variants of uncertain significance (and zero benign variants) with comparable evidence of selection to known pathogenic variants (including 86 in TP53 , 35 in NOTCH1 and 5 in PPM1D ) (Supplementary Table 4 ).
Other covariates, such as study design, geographical region, and tumor stage, also exhibit p -values approaching significance as summarized in Table 3 .