The correlations were indeed significant for the written language measures ( p ’s < 0.05), with the vocabulary measure approaching significance, r = 0.374, p = 0.095.
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“approaching significance”
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In LUSC-BM, ADC values were positively driven by K trans (β=16.55, p<0.0001) and CER (β=1.941,p=0.005),but negatively associated with Ve(β=−4.685,p=0.008),Vp(β=−16.66,p=0.002),iAUC 90 (β=−49.22,p=0.005),and K ep (β=−1.638, p=0.001), with Max.Slope approaching significance (β=8.903, p=0.095).
Additionally, the rate at which IgE increased with age tended to differ between sBBM Gimap5-DR and Gimap5-DP, approaching significance (p = 0.096).
For the waitlist control arm, compared to the mean score of 25.20 (SE = 3.29) at 8 weeks, the improvement was significant ( p = 0.0175) after the intervention at 16 weeks (MS = 35.64, SE = 2.94) and approaching significance ( p = 0.096) at 24 weeks (MS = 36.2, SE = 3.41).
On their own, frataxin levels did not predict change in FARS scores (p = 0.503); however, when using multivariate regression analysis to assess the effect of frataxin levels on rate of FARS change controlling for the effect of age and sex, the model was statistically significant (p = 0.002) with age as the main predictor of progression (p<0.001) and frataxin levels approaching significance (p = 0.096).
Further linear regression was corrected for the influence of confounding factors, and the results indicated that WMH could still independently related to the thickness of the entorhinal cortex (baseline level, p = 0.016; change slope, approaching significance, p = 0.096; see Figure 7 and Supplementary Table S13 for details), but not other indicators (data not shown).
The DMN showed significant age effects for the clustering coefficient (F(1,72) = 5.97, p = 0.017, η 2 = 0.075) and approaching significance for the degree (F(1,72) = 2.84, p = 0.096, η 2 = 0.037), with younger participants having higher values in both measures.
Respirable dust exposure levels showed a borderline significant association, with the high exposure group approaching significance compared to the low exposure group ( p = 0.096).
Moreover, the analgesic effect decreased more slowly, whereas in men, a sharp relief peak was reached at week 4, followed by rapid decrease, with the overall difference approaching significance (PPR effect of time × sex: F = 2.313, P = 0.097, partial η 2 = 0.035).
Although there did not seem to be a definitive survival advantage between the two pre-ECMO groups, Kaplan Meier log-rank test did show that it was approaching significance (p = 0.097).
CRIB II scores were lower in infants with the earliest initiation of enteral feeding (<12 h), and they clinically achieved full enteral feeding more quickly with results approaching significance ( p = 0.0971).
Other variables including creatinine, LDL, total cholesterol, triglycerides (approaching significance, p = 0.0980), hypertension status, and age group did not achieve statistical significance.
VO 2max showed significant declines with age (β 2 = −0.823, p = 0.012) and lower values in females (β 1 = −4.204, p < 0.001), with an age-by-sex interaction approaching significance (β 3 = −0.856, p = 0.098), suggesting a steeper decline in aerobic fitness with age in females.
Pairwise t -tests (Bonferroni corrected) showed the difference between positive ramp sawtooth and sham to be approaching significance ( p = 0.098), whereas p > 0.5 for all other condition pairs (cf.
This latter interaction appeared quite complex and to a small degree also dependent on the task (the 3-way interaction approaching significance, p = 0.098).
The gender difference in total traumas experienced was approaching significance [ F (2, 1007) = 2.75, p = .098], with males ( M = 7.02; SD = 6.47) reporting more traumas than females ( M = 6.34; SD = 4.63).
At 16-weeks the treatment effect was non-significant ( F (1,106) = 0.32, p -value = 0.58) while the treatment by time interaction was approaching significance ( F (3,106) = 2.14, p -value = 0.099).
However, the group immunized with live dpB IV (group 1) showed lower CFU/mL (approaching significance, M-W, p = 0.099) compared to the untreated control group.
In the anticipation condition, the difference between the high and low SAs group was approaching significance, t (44) = 1.8, P < .10.
A summary of the numbers of biochemicals that achieved statistical significance (p ≤ 0.05), as well as those approaching significance (0.05 < p < 0.1), is shown in Table 1 .
Furthermore, caspase-14 protein in both groups was suppressed to a level approaching significance after 24 hours of treatment (P < 0.1).
When the assumption on equality of variance (tested using Levene’s test) was violated ( p < 0.05 or approaching significance at p < 0.10) Welch homogeneity correction was applied.
Variables that were significant or approaching significance with p ≤0.10 in their respective univariate models were considered as covariates in the multivariable models.
In the second PU model, the coefficient for Aloof (AF) was -0.13 with a p-value approaching significance ( p < 0.1).
A p value <0.05 was considered significant, with effect sizes reported for comparisons approaching significance (0.05 < p < 0.10).