Several histopathological parameters indicated a higher degree of biological aggression in the IHC-loss group: Tumor Necrosis: Microscopic coagulative necrosis was detected in 7 of 19 IHC-loss tumors (36.8%), whereas it was present in 36 of 195 wild-type tumors (18.5%) ( p = 0.050; borderline significance).
The benefit of prehabilitation appeared more pronounced, with borderline significance, in patients undergoing “other” (non-colorectal) surgeries (RR = 0.54, 95% CI 0.30 to 0.99, p=0.05) compared to those undergoing colorectal surgery (RR = 0.73, 95% CI 0.39 to 1.34, p=0.31).
29.48 kg/m2), with borderline significance (p = 0.05).
For the secondary outcomes, there were significant reductions in fasting plasma glucose (−0.22 mmol/L; 95% CI: −0.39 to −0.04; p = 0.01; I 2 = 94%) and fasting insulin levels (−3.36 μIU/mL; 95% CI: −6.31 to −0.41; p = 0.03; I 2 = 97%), while a borderline significance in HOMA‐IR scores (−0.56; 95% CI: −1.12 to −0.01; p = 0.05; I 2 = 96%) but no significant differences in 2‐h OGTT or HbA 1 c measures.
A negative correlation was observed for eHbA1c and total daily and mild hypoglycemic events (r=−0.57 and r=−0.66, respectively, p<0.0001), whereas for serious hypoglycemic events there was only a borderline significance (r=−0.13, p=0.05).
The variability around that rater’s average for each screw size was also smaller for the repeated measurements compared to initial measurements, with borderline significance ( p = 0.05).
There was no significant difference found for SBP ( p = 0.712) and borderline significance for the DBP ( p = 0.050) between the groups.
Notably, significant disparities emerged across CDAI quartiles in terms of age, race, BMI, annual household income, and hypertension prevalence ( p < 0.001); while diabetes mellitus showed a borderline significance ( p = 0.050) and was subsequently included as a study covariate.
Cases of deuteranopia showed significant improvement ( p = 0.04) and cases of deuteranomaly showed borderline significance ( p = 0.05).
A borderline significance was observed in STEMI patients compared with CAC-positive individuals (p = 0.05).
Hepcidin levels were decreased after 12 weeks of roxadustat administration, with borderline significance in the entire cohort {140.2 ng/ml [interquartile range (IQR) 85.2–194.4] versus 110.5 ng/ml [IQR 46.1–167.1], P = .050} (Table 1 ).
Anxiety severity differed by age group (p = 0.036) but not by gender (p = 0.667), whereas depressive symptoms showed borderline significance across age groups (p = 0.050) and no gender differences (p = 0.222).
Ma et al (2003) retrospectively investigated, by immunohistochemistry, MGMT protein expression in melanoma metastases of 79 patients with metastatic melanoma receiving DTIC as single agent or as part of combination therapy, and reported an inverse correlation between MGMT expression and clinical response with borderline significance ( P =0.05).
The UACR exerted borderline significance for this dependent variable (OP = 1.04; p = 0.050). 3.6.
Septations were more frequently identified on MRI (32, 47.8%) than on USG (23, 34.3%), showing borderline significance (p = 0.05).
Hypertension prevalence demonstrated borderline significance ( p = 0.050) ( Table 2 ). 3.3.
The borderline significance was defined as the P ≥ 0.05, but < 0.10 (0.05 ≤ P < 0.10).
29%, p = 0.023), and borderline significance for pharmacologically treated type 2 diabetes mellitus (17% vs. 26%, p = 0.05).
When stratified by the antifibrotic type, a significant increase in fatigue was observed in the pirfenidone group (RR: 1.47, 95% CI: 1.15–1.87; I 2 = 0%), while nintedanib group showed a borderline significance (RR: 1.51, 95% CI: 0.99–2.30, p = 0.05; I 2 = 0%; Supplemental Figure 5 ).
In the TVC-adjusted multivariable model, the same variables remained significant, and ECOG PS ≥ 1 showed borderline significance ( p = 0.05).
gondii seropositivity was higher in patients with reflex impairment (27.8%) than patients without this impairment (8.8%), and this difference showed a borderline significance ( P = 0.05).
Multivariable logistic regression analysis revealed that the downgrade rate was higher in the GBCA change group with borderline significance (adjusted OR: 2.57, 95% CI: 1.00–6.60; P = 0.05).
The tissue Doppler-derived E/A ratio showed only borderline significance between GRACE-defined risk groups (P=0.050).
Patients with obesity were more likely to develop PSS than those without obesity, with the difference showing borderline significance ( P = 0.05).
Specifically, GLS exhibited a decrease during chemotherapy compared to the baseline, demonstrating borderline significance 18.5±2.3 versus -19.6±1.6 (p=0.05).