“borderline significance”

DZ_GC (6.00%; 4.10–7.73% vs 2.53%; 1.15–3.62%) and LZ_GC (14.59%; 11.28–19.52% vs 8.17%; 5.18–10.52%) showed higher proportions in AH with borderline significance (both P = 0.057).

The multivariate adjusted HR for CHD according to a doubling of adiponectin levels at baseline was 0.60 (95% CI 0.35–1.02), with borderline significance ( P = 0.057).

Among these genes, the expression of four of them (DCN, FN1, MMP2, and PLAU) was significantly correlated to AXL expression (R 2 range: 0.76–0.86; p value range: 0.0048–0.00012), while that of CDH11 showed an R 2 = 0.48 but a borderline significance ( p = 0.057 ), and the expression of three of them (CXCL12, TGFB1, and ZEB2) was not correlated to AXL ( Supplementary Fig. 5 ).

MMSE scores were lower in the glaucoma group than in the non-glaucoma group, but this difference showed borderline significance ( P = 0.057) (Table 5 ).

In the bivariate analysis of prognostic factors, IIAT appears to be associated with mortality, with a borderline significance ( p = 0.057).

Furthermore, high expression of ITGB1 was correlated with late clinical stages in both cohorts ( P = 0.019, P = 0.016, respectively) and with lymph node metastasis but with borderline significance ( P = 0.057, P = 0.062, respectively).

We found a borderline significance at the latest time points (T3, p = 0.057; T4, p = 0.095), suggesting that patients keeping high levels of plasmatic cfDNA while receiving systemic therapy might have a worse outcome (Fig. 4 ).

hsCRP was only correlated with %CD4 + RTE (r = − 0.326; p = 0.049) and with %CD4 + HLA-DR + with borderline significance (r = 0.316; p = 0.057) (Additional file 2 : Figure S1).

The AC genotype was also associated with an increased risk of MPN, but the P value for Chinese was at borderline significance, likely due to relatively few patients (AC vs AA: OR = 2.02; 95 % CI: 1.00–4.08, P = 0.057, for Chinese, and OR = 1.89; 95 % CI: 1.05–3.41, P = 0.034, for Swedish).

On multivariate analysis (MVA), the association remained statistically significant for lines of chemotherapy (HR, 2.58; 95% CI, 1.42-4.66; P = .002) and lesion size (HR, 1.94; 95% CI, 1.04-3.60; P = .037), whereas borderline significance was observed for BED10 (HR, 1.83; 95% CI, 0.98-3.42; P = .057; Table 2 ).

Of all these variants, only the ATM mutation c.8560C>T was found significantly increased in our PrCa patients comparing with our healthy controls ( P = 0.024; S3 Table ), with the CHEK2 mutation c.349A>G reaching borderline significance ( P = 0.057).

There were no significant between-group differences in postoperative GCS or mRS, but the mRS score in the MIN group (mean, 3.5 ± 1.34) was lower than that in the craniotomy group (mean, 4.1 ± 1.36), with borderline significance ( p = 0.057).

For the transition from T2DM to multimorbidity, no associations were observed during 0-<1 or 1-<3 years, with borderline significance at 3–<5 years (HR, 1.12; 95% CI, 1.00-1.25; P = 0.057) and significant elevation thereafter (≥5 years: HR, 1.14; 95% CI, 1.05-1.25; P = 0.003).

Interestingly, the SOD2 mRNA expression level was increased in soleus of THP-treated as compared to CTL rats, reaching borderline significance (Figure 6A ; p = 0.057).

The difference had only borderline significance in the infective flies (U = 0.00, d.f. = 33, p = 0.057), as there was only one infective S . yahense with 17 L3s, despite the large difference between this and the mean in S . sanctipauli of 2.12 ± 0.56 L3/infective fly.

Il6 and Map1lc3a correlated with ear wound healing and correlated in the same direction with articular cartilage regeneration with borderline significance ( P = 0.057 and P = 0.085, respectively).

Univariate analysis revealed significant differences in swelling at the 5 cm above patella site among the four strength change patterns (Kruskal-Wallis H = 11.780, P = 0.008), with borderline significance at the 10 cm above patella site (H = 7.525, P = 0.057).

The Chi-square test showed borderline significance (χ2=3.625, df=1, p =0.057), suggesting a possible but inconclusive link between gender and DM type, requiring additional investigation.

However, after normalisation to weight only borderline significance was seen for females ( p = 0.0570) and for males ( p = 0.0524).

As expected, more patients in the older age group presented with Killip class >II, and we observed borderline significance (p = 0.057).

Predictors of Cardiac Overload or HF Risk Multivariate logistic regression identified three independent predictors of falling into the “HF likely” or “HF very high-risk” categories ( Table 3 ): AECOPD within the previous 30 days (OR 9.0, 95% CI 1.5–54.7; p = 0.017), lower hemoglobin levels (borderline significance, p = 0.057), and number of antihypertensive medications (OR 2.7, 95% CI 1.1–6.6; p = 0.031).

In the ≥ 70-year subgroup, the protective effect of NHAPI race/ethnicity remained statistically significant ( p < 0.001), whereas the adverse effect associated with NHB race/ethnicity was of only borderline significance ( p = 0.057).

However, since borderline significance emerged for the medium dose (p = 0.057), we are unable to establish whether our sample size of 30 plans could have determined the lack of significance.

We also compared the distribution of the characteristics in Table 1 between the 1008 study patients and the 230 excluded patients, the differences were not statistically significant (all P > 0.05) except for sex with a borderline significance ( P = 0.057).

Male sex and HF were significant determinants; atrial fibrillation and CKD had a borderline significance ( P =0.057 and P =0.070, respectively); and diabetes, COPD, and peripheral arterial disease were not significant and thus were not included in the multivariate equation.