Cartilage damage Evaluation of Saf O stained cartilage sections showed a small increase in OARSI cartilage structural damage score in experimental (OA) knees compared to contralateral control knees (2.5 (95%CI: 0.6–4.4) points out of 12 points) in the PBS treated group, which was normalized in the cIL4-10 FP treated group (0.7 (95%CI: -0.6–2.0) points), at borderline significance (p = 0.057, Fig 8B ).
Factors associated with patients’ overall quality of life (QOL) and its domains In logistic regression analysis factors significantly associated with overall score of QOL for HHC patients were marital status (OR = .516, 95% CI [.293, .910] p = .022,), psychological problems (OR = 5.95, 95% CI [1.98, 17.93], p = .002) and stroke (OR = 2.10, 95% CI [1.07, 4.11], p = .031) while the number of illnesses has a borderline significance on overall QOL (OR = 1.47, 95% CI [0.99, 2.20], p = .057,).
Concentrations of PCho, a choline storage form and intermediate in the cytidine-diphosphocholine (CDP) choline pathway for PtdCho synthesis, were also significantly lower due to the Mthfr +/− genotype, as were the concentrations of PtdCho and its catabolite SM, with borderline significance for another catabolite, LysoPtdCho ( P = 0.057).
PP EX analyses additionally showed significant between-group differences in favour of adherent EX for physical functioning (pre–post 0 : P = 0.014, ES = 0.63), role functioning (pre–post 0 : P = 0.02, ES = 0.48) and fatigue (pre–post 0 : P = 0.016, ES = 0.45), and borderline significance for pain (pre–post 0 : P = 0.057, ES = 0.32).
The potential influence of daratumumab exposure before EloPd salvage therapy showed borderline significance in the univariable analysis (HR 1.50, P = 0.057), but this association was not retained in the multivariable model (HR 1.21, P = 0.41).
Notably, while Adenoid Size was significant in univariate analysis, it showed only borderline significance in the multivariate model ( P = 0.057), suggesting its effect might be partially captured by other variables or is less critical than tonsillar size in this specific cohort. 3.5 Diagnostic performance (ROC analysis) To evaluate the translational potential of these findings, Receiver Operating Characteristic (ROC) curve analysis was performed ( Table 5 and Figure 3 ).
Early CRC does not have self-identified symptoms” showed a borderline significance increase in correct response ( p = 0.057) in low eHL group in this Internet-based study, this statement could show a statistically significant increase in correct responses in the future study with a large general population-based study.
Among these genes, the expression of four of them (DCN, FN1, MMP2, and PLAU) was significantly correlated to AXL expression (R 2 range: 0.76–0.86; p value range: 0.0048–0.00012), while that of CDH11 showed an R 2 = 0.48 but a borderline significance ( p = 0.057 ), and the expression of three of them (CXCL12, TGFB1, and ZEB2) was not correlated to AXL ( Supplementary Fig. 5 ).
Furthermore, high expression of ITGB1 was correlated with late clinical stages in both cohorts ( P = 0.019, P = 0.016, respectively) and with lymph node metastasis but with borderline significance ( P = 0.057, P = 0.062, respectively).
Only borderline significance was found between serum insulin and dopamine ( r = −0.16, P = 0.057).
Of all these variants, only the ATM mutation c.8560C>T was found significantly increased in our PrCa patients comparing with our healthy controls ( P = 0.024; S3 Table ), with the CHEK2 mutation c.349A>G reaching borderline significance ( P = 0.057).
In TCGA validation cohort, there was also a trend of higher methylation of the − 796 CpG island correlating with shorter disease-free intervals, with borderline significance ( P = 0.057).
Although the crude relapse rates appeared different between the two treatment groups, the difference did not reach statistical significance (borderline significance, P = 0.057).
The effect of UMC on asthma in the entire PASTURE population (aOR: 6.73, 95% CI 2.77–16.34, p < 0.001) was also present within the Finnish arm (aOR: 13.42, 95% CI 3.17–56.89, p < 0.001), and with borderline significance in the other centers (aOR: 3.99, 95% CI 0.96–16.63, p = 0.057).
14-3-3 σ overexpression was statistically significantly associated with pT-stage (p=0.041) pN-stage (p=0.015) and UICC-stage (p=0.019) and showed a borderline significance with Lauren classification (p=0.057).
A borderline significance of uKIM-1 in predicting CKD stage 3 independently in the community-based population was observed (pooled adjusted relative risk: 1.13[1.00 to 1.27], p = 0.057).
The interaction effect of stimulation status × type appeared borderline significance in ODD, f = 3.10, p = 0.057, η 2 = 0.09.
When analyzed separately, gingival BMP-2 levels revealed a causal relation with the degree of periodontal pathology with borderline significance only in patients with acromegaly (p = 0.057).
Although major depressive disorder (MDD) shows only borderline significance (p = 0.057), the possible influence of TEs on serotonin levels suggests that TEs might be involved to a certain degree.
And there was borderline significance in the comparison of hs-cTnI levels between the hypertension and nonhypertension control groups ( p = 0.057).
Anterior circulation involvement was more frequent in old smokers with borderline significance (83.1% vs. 76.5%, P=0.057).
Reaction times showed here only borderline significance (effect of genotype P = 0.057).
Perioperative: haemoglobin and transfusions Hb values were lower in SCD patients both preoperatively (8.1 [7.1–9.4] vs 11.8 [10.0–13.0] g/dl, P < 0.001) and at discharge, with a borderline significance (7.9 [7,2–9.5] vs 9.3 [9.1–10.5] g/dl, P = 0.057).
For compliance with IFA for at least 180 days, the following variables were significantly associated with higher odds of compliance: respondent’s age of 35–49 years (aOR 1.51, 95% CI 0.99–2.31, p = 0.057, borderline significance), respondent’s educational qualification of higher (aOR 2.45, 95% CI 1.34–4.48), husband’s educational qualification of higher (aOR 1.36, 95% CI 0.89–2.10, p = 0.156, not significant), not working during pregnancy (aOR 1.24, 95% CI 1.01–1.52), and having received at least four ANC visits from medically skilled providers (aOR 2.43, 95% CI 1.97–3.00).
Only in the nasal sector the CON group had correlation with borderline significance ( p = 0.057).