The Women's Health Initiative trial found borderline significant associations between 25(OH)D levels and menopausal symptoms such as sleep disturbance, emotional well-being, and energy/fatigue [ 52 ].
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Although the aforementioned correlations between immune parameters and in vitro/ex vivo response patterns were weak (in the sense that they were only borderline significant), we hypothesized that PD-L1 and/or CD95 on circulating CD4 + and CD8 + T cells might predict resistance to CTLA-4 blockade in MMel.
A previous meta-analysis [ 8 ] found borderline significant benefits for MBIs on cognitive functioning in PwMS.
Of the remaining 23, 19 were firm replications and 7 were borderline significant.
Surprisingly, in our study, a borderline significant increase in colorectal cancer mortality was observed for the moderate compared to the low adherence group.
We observed a lower locomotor activity in HFD-fed, InsR-Ctrl male mice compared to InsR-KO mice during the light (inactive) phase ( Figure 2 K,L), which was borderline significant for 24 h ( Figure 2 M).
Moreover, a borderline significant association was observed between rs3757328 and the HCC risk (adjusted OR = 1.11, 95% CI = 0.96-1.28; Table 1 ).
those classified as pathological in the BC or that required hospitalization, and Italian women, the risk for CS in private care was higher and borderline significant (OR: 1.16 95% CI: 0.93 – 1.44).
The initial dose-induced plasma level changes of the above spots 195 and 529 showed again an association with the final response to therapy with a P -value of 0.047 for spot 195 and a borderline significant P -value of 0.054 for spot 529.
In our study, mobile equipment was borderline significant.
All statistical comparisons were two-tailed, and a P value < 0.05 was considered statistically significant; a P value comprised between 0.05 and 0.10 was considered borderline significant.
For fibrinogen, there was no significant association with risk of nonfatal CVD, but borderline significant associations were evident with each of the CVD mortality endpoints ( Table 3 ).
Leptin in HM of mothers with female compared to male offspring was 30% higher in the initial model, however, only borderline significant.
We also observed a borderline significant positive association with risk of pancreatic cancer for those with higher levels of CRP (≥10 mg/L) compared to those with CRP levels < 10 mg/L [HR: 1.32 (95% CI 1.00–1.74)].
Educational status was also significantly associated with zero ANC uptake; women with primary education (AOR = −0.707, 95% CI: −0.989, −0.425) were substantially less likely to have zero ANC visits, while those with secondary (AOR = −0.596, p = 0.062) and higher education (AOR = −1.202, p = 0.059) showed similarly strong but borderline significant reductions in zero utilization.
For short-term poor prognosis, multivariate logistic regression showed that elevated TyG index was an independent risk factor, with a borderline significant P value of 0.068.
Sensitivity with single item AUDIT-C showed similar results for life satisfaction, but a borderline significant result for mental distress (see online supplemental tables S16 and S17 in Appendix).
CRC screening increased significantly with educational level and showed a borderline significant association with older age among men but not women.
During the 2009 heatwave, a borderline significant increase in total mortality (IRR 1.10; 95% CI, 0.99-1.22) was observed with a significant increase of 37% (IRR 1.37; 95%CI, 1.09-1.71) in the 15-64 year age group.
Observing in more detail the pathway activation scores in Figure 1 G, we found that only the EIF2 pathway was strongly inhibited in f-LSECs (Z score below 2 in all comparisons), whereas ATM signaling showed a borderline significant Z score, indicating activation in f-LSECs. 2.4.
Discussion In this prospective study of young adults, we found an eight per cent net increase over a ten-year period in self-reported rhinitis and nasal allergies, a borderline significant decrease in the prevalence of wheeze in the last 12 months, and an increase of Dr diagnosed asthma and waking up with shortness of breath in the last 12 months.
The backward stepwise elimination of non-significant factors ( step function in the lmerTest package, Kuznetsova, Brockhoff, & Christensen, 2017 ) was used to reduce the models with an alpha level set to 0.1 to avoid stepping out borderline significant factors.
There was a borderline significant interaction between delivery mode and pre-pregnancy BMI on our a priori hypothesized genus of interest, Bacteroides ( p for interaction = 0.05).
However, when patients were informed the resident would be supervised by an experienced cataract surgeon, the impact of watching the video on patient willingness to have their cataract surgery performed by a resident was only borderline significant; of note, a larger sample size may have yielded a statistically significant result.
5.2 R2: To what degree are Google's data on changes in park visitation attributable to the COVID-19 pandemic? Of the independent variables directly related to COVID-19, only median age and duration of safer-at-home orders were shown to have a borderline significant prediction of park visitation.