In the sensitivity analyses, with the additional adjustment for ALT and AST, the results were materially unchanged, except for GCA and GCDCA, where P values became borderline significant (both P FDR = 0.06) (Supplemental Table 1 ).
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“borderline significant”
Sighted at
p=0.09
In the literature
A p-value between 0.05 and 0.1was considered borderline significant.
Some of the cancers with a non-significant overall p-value had borderline significant excess (e.g.
Except for hypertension and eGFR, similar differences were found in patients with a TnT release, in which the highest quartile also included more STEMI, with a borderline significant p-value of 0.06.
Because the results are borderline significant, they should be regarded with caution.
We also explored whether sIgE levels differed between males and females, but found no significant differences although sIgE to birch was higher in males (median 13.0 kU A /L vs 6.5 kU A /L, borderline significant after multiple test correction).
Besides, we found some SNPs with borderline significant associations with the risk of offspring SDs before FDR correction, and no such significant associations were found after FDR correction.
As a result, the models assessing disability had small effect sizes or were borderline significant.
While Zn-rich content was related to industrial emissions and urban areas [ 14 , 17 ], there was also found a higher concentration of Zn in urban areas than in rural areas with a borderline significant difference in the present study ( Table 3 ).
These sex differences were statistically significant or borderline significant for the frequency items related to partners and parents, and were consistently significant across all items for emotional impact (Table 2 ).
Younger age was borderline significant p = 0.058. 3.2.2.
In the same model, male employees had a borderline significant decrease in risk of reportable injury compared to females (HR 0.74 (CI 0.55, 1.00, p-value 0.05).
= not significant. on the whole population (n = 852) - to be significant (cell type) or borderline significant (age, stage).
P-values < 0.05 were considered statistically significant and p-values between 0.05 and 0.10 were considered borderline significant.
In contrast, the effects of the size-specific particulate matter on asthma are less robust: the moving average lags of PM c , and PM 2.5 were still significantly associated with the ALRI outpatient visits, but the effects of lag0 to lag5 of PM c and PM 2.5 and different lags of PM 10 were non-significant or at borderline significant.
Whereas we found no difference in 5-HT4R binding level at baseline between the groups, we observed a crossover interaction between the OC users and the non-users in the association between baseline 5-HT4R BP ND and treatment response, but notably, the association within each group was only borderline significant, which may be due to power issues.
In a sensitivity analysis controlling for age categorized into < 37 years and ≥ 37 years, the association between day-3 FSH and PP became stronger: The mean difference in day-3 FSH was 1.24 IU/L [95% confidence interval (CI): –0.18, 2.67] in tertile 3 [using age as a continuous covariate, the mean difference was 1.02 (95% CI: –0.40, 2.43)], and 1.19 IU/L (95% CI: –0.22, 2.60) in tertile 2 [using age as a continuous covariate, the mean difference was 1.16 (95% CI: –0.26, 2.57)], both compared with tertile 1 (with the p trend of 0.08 becoming borderline significant).
Discussion In one of the first investigations of this hypothesis using a GWAS approach, we identified a borderline significant association for rs100009124 and number of children when corrected for multiple comparisons in our analysis.
Similarly, TUNEL-positive cells ( Figure 3 A,B) in the PCD and DCT of Fin group were about one and a half times more frequent than the control; however, statistical values were borderline significant and only for DCT ( Table 4 ). 3.5.
Only early stage and young age (borderline significant for overall population only) were associated with a better overall survival (early disease with disease-free survival also).
Two other SNPs that showed a significant or borderline significant association with DN, each with an additive-effect, were rs6499323 ( IL34 ) and rs11647932 ( ST3GAL2 ) on chromosome 16q22.1 (Additional file 1 : Figure S1).
There was a borderline significant difference in the prevalence of nanI gene among the isolates from pulmonary tract and wound infections.
Fourth, in Tables 3 and 2 , several ORs and confidence intervals (CIs) appear small or borderline significant.
APC methylation was found to be a significant predictor of PC specific death when both cohorts were combined and was borderline significant in each of the two cohorts when analyzed separately ( Table 2 ) [ 54 ].
We have found a significant decline in serum TGF-β cytokine levels and borderline significant decreases in serum IL-6 and TNF-α cytokine levels.