8 , 20 , 21 , 22 , 23 , 24 Patients included in this, the MEGA study, showed a clearly significant association between severe asthma on the one hand and increased symptoms and exacerbations, lower disease control, greater airflow obstruction and higher frequency of CRSwNP, severe rhinitis, anxiety and depression, gastroesophageal reflux, and bronchiectasis on the other when compared to patients with milder disease.
Even if these data were collected retrospectively and no health status was carried out for the respective athletes before starting CrossFit training, a certain causality can be identified based on the relatively large group and the clearly significant difference to the group without simultaneous or previously performed sports suspected.
In the mixed linear regression model predicting log(R e ), the time trends were clearly significant and the 95% CIs around the estimated coefficients for day and day 2 clearly excluded the null effect (β day = −0.035 [95% CI −0.039 to −0.031]; β \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{upgreek} \usepackage{mathrsfs} \setlength{\oddsidemargin}{-69pt} \begin{document} }{}${\rm day}^{2}$\end{document} = 0.000 24 [95% CI 0.000 21 to 0.000 28]).
However, it was only when coding sequences were considered, instead of the whole genome, did differences become clearly significant ( Figure 1 B).
Within the coronaviruses, there is some degree of conservation that suggests that NCYWPLNDYGF is a segment for the virus to conserve, and a hint that FNCTWPGF is the key part, but there are soon very clearly significant variations across coronaviruses of different hosts as we depart from the Wuhan seafood market isolate compared with the RSFIEDLLFNKV motif in the S2’ cleavage regions [ 3 ].
Given the small number of clearly significant effects, we apply a gene set enrichment analysis approach to identify effects that are significant at the gene set level even though non-significant at the gene level.
Oxidative stress indicators, such as the whole-kidney MDA level, and ER stress marker CHOP did not show a clearly significant difference and relatively large variance was noted.
IJA deficiencies at 8 months were predictors of ASD early markers at 18 months, with values close to significance; whereas RJA deficits at 12 months were predictors of ASD early signs at 18 months, with clearly significant values.
Such annexin A5 increase in supernatant was clearly significant 24 and 48 hours after Aβ treatment (Fig. 3b ).
Clearly significant associations were observed between the MRS-High and the MRS_Medium groups and CRC risk among both the younger and the older participants.
Heat-related effects did not display a clearly significant pattern.
As could be seen, the comparison of analytical performance of our proposed glucose biosensors with selected ones that have been proposed by others in earlier publications in Table 1 perhaps don't have a very clearly significant advancement.
However, the measurements of coagulation activity were clearly significant, and in the patients with VTE, we were unable to confirm an increased coagulation activity, which is in accordance with a recently published larger study on patients with SCLC [ 46 ].
There are clearly significant pathological differences between severe, moderate and mild TBI and therapeutics will have different levels of benefits depending on injury severity.
When the equality of the means was tested by a permutation test, the p-value was 0.006, i.e., the differences were clearly significant.
Although this is not surprising, due to the antimicrobial properties of this fat [ 18 , 21 ], the fact of reaching higher representation later on at the end of the experiment, with a clearly significant predominance in Sutterellaceae and Erysipelotrichaceae [ 19 ], increased the expectations in this sense.
Confirming this hypothesis, levels of monoacylglycerols and diacylglycerols were in general decreased in TβT-Hep3B, being clearly significant in some cases, such as palmitoleoyl-oleoyl-glycerol or palmitoyl-linoleoyl-glycerol ( Supplementary Table S1 ), and the expression of LIPE (Lipase E or hormone-sensitive lipase) was increased in TβT-Hep3B cells (2.94 fold increase, p = 0.07).
The effects were clearly significant for end-expiratory flows and remained visible up to 24 h after exposure.
The difference in the ratios observed between the two groups is statistically significant with a risk of 10% for the total population analyzed ( n = 53; Student and Wilcoxon–Mann–Whitney tests); it is also clearly significant at the risk of 5% if we eliminate the extreme values (1 in each group) corresponding to two patients with a poorly defined professional project (withdrawal from ShE after 2 or 3 months, with absenteeism therefore during these few weeks of follow-up; Table 2 ).
However, in post hoc t tests the only clearly significant evidence for a nonzero Type B effect occurred for the 1,000-ms St duration, where the effect was negative (implying s 1 / s 2 < 1).
This is in stark contrast to our findings where the mean GAD-7 score was 9.2 (± 5.6) and the respective prevalence levels reached 35% and 21%, making the differences clearly significant.
Accordingly, the COD removal efficiencies of two systems were analyzed and it was found that high rate IAnA-BioGACSBR has clearly significant effect on COD biodegradation as compared to others.
The analysis revealed a slightly but significant bias in the case of the bone volume ( b i a s H i s t o − M R I : B o n e v o l u m e = 2.40 % , p < 0.005 ) and a clearly significant deviation for the remaining defect width ( b i a s H i s t o − M R I : D e f e c t w i d t h = − 6.73 % , p ≪ 0.005 ) .
Our experiments using Pol I inhibitors show that these two types of Pol I transcription complexes at either the rDNA or the active ES are inhibited in a similar fashion, although there are clearly significant differences in their control.
This indicates, as evident also from Tables 2 and 3 , that differences in performance between the tool on its own and CL are small but that the improvement is clearly significant when both are combined together.