However, examination of the outer T cell-rich zone of mTLS showed higher mean densities of CD8 and PD-1 positive lymphocytes in the PT cases, although this did not reach statistical significance ( p = 0.040 and 0.029).
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While there was a notable level of heterogeneity, it did not reach statistical significance ( I 2 = 97%, p = 0.04).
Response to lenzilumab was observed in the first through third quartiles of baseline CRP with the greatest lenzilumab treatment effect observed in the first quartile (CRP <41 mg/L; HR: 8.20; 95% CI 1.74 to 38.69; p=0.0079) and a numeric difference that did not reach statistical significance in the second quartile and a significant treatment effect observed in the third quartile (CRP 79<137 mg/L; HR: 2.25; 95% CI 1.04 to 4.88; p=0.0407 ( table 3 )).
Although most gastrointestinal symptoms did not reach statistical significance, early satiety ( p = 0.041) and functional deterioration ( p = 0.039) were significantly associated with irinotecan administration, while nausea ( p = 0.089) and vomiting ( p = 0.087) showed trends toward significance.
However, the DeLong test indicated that the AUC difference between the combined and clinical models did not reach statistical significance (P = 0.041), and the difference with the RDL model also did not reach significance (P > 0.05) ( Figures 3C ).
Interestingly, flatulence sensation paralleled intestinal gas evacuation and reverted to the level before administration, but the other sensations remained above pre-ingestion level; the differences between late ingestion and pre- ingestion levels were small and did not reach statistical significance, except for abdominal discomfort ( p = 0.041).
After 3 years' median follow-up, the PFS difference between atezolizumab and placebo did not reach statistical significance in the ITT (hazard ratio [HR], 0.83; 95% CI, 0.69 to 0.99; P = .041; median 13.5 v 11.3 months, respectively) or PD-L1–positive (HR, 0.86; 95% CI, 0.63 to 1.16; P = .30; median 15.2 v 13.1 months, respectively) populations.
The mean serum P 4 level on the day of the hCG trigger was higher in the GnRHa group (2.54±1.56 ng/mL) than in the CC+hMG group (0.75±0.38 ng/mL); however, these results did not reach statistical significance ( p =0.041).
Although the difference in Psychological Discomfort ( p = 0.094) did not reach statistical significance, the Functional Limitation domain stands out ( p = 0.041).
After 3 years’ median follow-up, the PFS difference between atezolizumab and placebo did not reach statistical significance (median 13.5 vs 11.3 months, HR=0.83; 95% CI=0.69–0.99; p=0.041) or in PD-L1-positive (median 15.2 vs 13.1 months, HR=0.86; 95% CI=0.63–1.16; p=0.300) populations.
In the peripheral analysis, there was a trend toward an enhancement of SNR after a-tDCS stimulation ( b = 0.014, P = 0.052), but it did not reach statistical significance; latency was increased after tACS ( b = 1.623, P = 0.041).
did not reach statistical significancep = 0.0414
However, this result should be interpreted with caution, as the observed difference was small and did not reach statistical significance in the non-parametric analysis (Kruskal–Wallis, H(3) = 8.24, p = 0.0414; Dunn’s test BH-adjusted p = 0.1960).
For BID, this trend did not reach statistical significance, whereas Caspase-8 showed significantly higher expression in the crown region ( p = 0.042).
33%) did not reach statistical significance, the treatment group showed later onset of recurrence (9.5 vs. 2.9 weeks, p = 0.042), a lower rate of advanced PVR ( p = 0.038), and significantly better final visual acuity outcomes ( p = 0.035) [ 51 ].
16 Unfortunately, the overall survival (OS) benefit of nivolumab compared to sorafenib did not reach statistical significance according to the pre-defined threshold in the trial design (HR, 0.84; P =0.042).
There was also a strong reduction of SGN densities in the acute group in relation to the control level, although it did not reach statistical significance (71.5 ± 9.0; p = 0.042) ( Fig. 4 ).
Although this result did not reach statistical significance after adjusting for multiple comparisons using the FDR method (P-FDR = 0.331), the odds ratio (OR = 1.054, 95% CI: 1.001–1.108, P = 0.043) suggests a marginal relationship between BC and FI.
The reduction in CoQ 10 concentrations in blood did not reach statistical significance. α-tocopherol concentrations were reduced to 82.1% ( p = 0.043), 79.6% ( p = 0.022), and 72.0% ( p = 0.037) in blood, plasma, and PLT in comparison to the healthy men ( Figure 3 A–C). γ-tocopherol concentrations in the blood, plasma, and platelets of the infertile patients were also lower than those in the healthy controls; however, these declines did not reach statistical significance ( Figure 3 D–F). 2.4.
Relative to PreTRM, the Model demonstrated a higher AUC and sensitivity in predicting LOS associated with sPTB, which was significant for AUC but did not reach statistical significance for sensitivity ( p = 0.044, and p = 0.263 respectively).
In addition, the differences in other intraoperative measures, such as simultaneous cataract surgery and type of endotamponade substances, did not reach statistical significance, except for a lower percentage of patients who underwent suturing after surgery in the 27G group ( P = 0.044).
Although physicians in basic sciences also scored higher than those in surgical specialties did, this difference did not reach statistical significance ( p = 0.044).
However, for Total Problems, pairwise comparisons did not reach statistical significance (mean difference = −9.12, SE = 3.28, p = 0.044 (Bonferroni correction: α = 0.008), d = −1.23, 95% CI [−18.08, −0.15]) although the effect size was large (d > 0.50).
While an increase in STD HR was observed between resting time (5.92 ± 3.53 ms) and bike ride (11.2 ± 21.35 ms), this change did not reach statistical significance ( p = 0.044).
0.50 ± 0.11), the difference did not reach statistical significance ( p = 0.045 in some comparisons, trend level in others).
However, mCCI >1, which did not reach statistical significance in the unadjusted analysis, after matching was significantly higher in the elderly group compared to the younger cohort (19.4% vs. 10.9%, p = 0.045) ( Table 1 ).