While most correlations did not reach statistical significance, a notable exception was observed for H18 dosage (r = 0.39, p = 0.015) (see Additional Table 1 ).
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The sex difference for the Maximum XYZ expression did not reach statistical significance while the sex difference for the Maximum SVD expression showed the opposite sex difference ( p = 0.015).
patients with GOS score 1), increased in-hospital delirium burden was significantly associated with worse GOS at discharge but did not reach statistical significance for GOS at 3, 6, and 12-months after adjusting for covariates (GOS at discharge [N = 129]: aOR, 0.03; 95% CI, 0.00–0.36; P = .015; 3 months [N = 124]: aOR, 0.90; 0.24–3.35; P = 0.880; 6 months [N = 121]: aOR, 0.70; 0.18–2.47; P = .558); 12 months [N = 110]: aOR, 0.49; 0.12–1.94; P = .312).
Clavien–Dindo IIIa complications were reported in 13.0% (3/23) of NOSE-LRR patients, with no events in the other two groups; this difference showed a trend but did not reach statistical significance ( p = 0.015).
In COPD subjects, a similar pattern was observed, but did not reach statistical significance ( P =0.015).
There was a trend for decrease in the fiber volley amplitude of the global KO brain slices during 0.6% ISO exposure when compared to the control brain slices, however the change did not reach statistical significance (p = 0.015).
did not reach statistical significancep -value = 0.015
Furthermore, overlapping with the age-stratified cohort (Corley et al., 2019), our PBMC signatures aligned strongly with the post mortem brain of the young cohort, such as in all ASD with 25 overlaps at a 76% consistency rate (hypergeometric p -value = 4.45 × 10 −15 , adjusted p -value = 5.34 × 10 −14 ), however, directional consistency across these age-stratified groups did not reach statistical significance (binomial p -value = 0.015 and adjusted p -value = 0.050) [ 28 ].
Although the loss of lean mass in the PL group (3.3%) and the gain in the TE group (3.2%) did not reach statistical significance, the difference in the percent change between groups was significant ( p = 0.015).
By contrast, dmPFC encoded model-based confidence estimates on both trial types: activity decreased with confidence on other-trials, but increased with confidence on self-trials, although the effect on self-trials did not reach statistical significance (c-HRF regression; confidence on other-trials, t (20) = −2.67, p = 0.015; confidence on self-trials, t (20) = 1.79, p = 0.089).
The comparison between AD and non-neurologic disease controls did not reach statistical significance following multiple testing correction ( p = 0.015).
Microglia cell count was partially rescued by all constructs, although this did not reach statistical significance (Figure 4 f, p = .0152).
A decreasing trend of circ_0000160 was found in breast cancer tissues with more advanced N stages (increasing ALNM number, Figure 3A , one-way analysis of variance, p = 0.0157); however, the comparison for every two stages did not reach statistical significance (N1 vs.
Adjusted odds ratios also suggested that consumers living in small/rural communities were somewhat more likely to drive after cannabis use, but this contrast did not reach statistical significance ( p = 0.016).
For all tested materials, at both the 24 h and 48 h time points, the LDH assay revealed only minor variations that did not reach statistical significance, with the exception of sample M2 at 48 h, where a statistically significant decrease was observed ( p = 0.016) ( Figure 2 A).
In the carbetocin 9.6 mg arm, trends toward numerically greater improvements in HQ-CT and CGI-C scores relative to placebo were observed but did not reach statistical significance; however, the carbetocin 3.2 mg arm demonstrated a significant improvement in HQ-CT scores (LS mean improvement vs placebo -3.14 points, p=0.016).
However, the difference between using one stick and other forms of aids did not reach statistical significance (p = 0.016, chi-squared test).
Although the NoGo-P3 amplitudes decreased and exhibited a dose-dependent pattern along with prolonged time of TSD ( Table 2 ), the difference did not reach statistical significance ( p < 0.016).
When the PF and PX induction regimens were combined for evaluation of the IC + CCRT group versus the CCRT + AC group, unadjusted comparisons did not reach statistical significance, but adjusted comparisons indicated a reduction in the hazards of disease progression (HR, 0.67; 95% CI, 0.48–0.93; P =0.016) and death (HR, 0.57; 95% CI, 0.39–0.86; P =0.006) ( 37 ).
In addition, pair-wise comparisons of consecutive probe doses higher than 0.193 nmol did not reach statistical significance at any NMDA level with the exception of 0.313 nmol versus 0.387 nmol at 2.5 mM NMDA (p = 0.016).
did not reach statistical significancep = 0.0161
In contrast, recurrent IF was associated with reduced HDAC2 activity relative to Fast‐Single, although this effect did not reach statistical significance compared with controls ( F (4,20) = 3.944, p = 0.0161, Figure 2D ).
did not reach statistical significancep = 0.0164
The PD-1 inhibitor, pembrolizumab, combined with platinum/etoposide numerically improved mOS compared to platinum/etoposide alone in the phase III KEYNOTE-604 trial, but this did not reach statistical significance (10.8 vs 9.7 months, p = 0.0164). 37 , 38 Ipilimumab was investigated in a phase II trial with platinum/etoposide first-line but did not improve mOS compared to platinum/etoposide alone. 39 The TIGIT inhibitor, tiragolumab, was investigated in the SKYSCRAPER-02 phase II trial in combination with carboplatin/etoposide but did not produce an improvement in mPFS or mOS. 40 Additionally, ICIs have been investigated as a maintenance-only therapy.
did not reach statistical significancep < 0.0167
The number of IL-10 producing cells in group R was higher than in group A ( p = 0.0338), but did not reach statistical significance by The Bonferroni/Dunn analysis in which significance is defined as p < 0.0167.
Although the overall and pairwise comparisons among 4 study arms did not reach statistical significance (due to the Bonferroni correction for multiple comparison; p ≤0.017 was considered statistically significant in the pairwise comparision), the diet+exercise group reduced depression (Δ Diet+Exercise = -1.7 points, p = 0.03; vs. control Δ Control = 0.7 points) and increased social support (Δ Diet+Exercise = 1.0 points, p = 0.05; vs. control Δ Control = -2.8 points).
Analysis on matched PRFs showed that patients perceived that they discussed other PD-related conditions less frequently than physicians perceived although this difference did not reach statistical significance (matched patients vs matched PRFs, P =0.017).
While the difference did not reach statistical significance after Bonferroni correction, a marginal trend towards better survival was observed in the CTD-UIP group compared to the asbestosis-UIP group ( p = 0.017).