“did not reach statistical significance”

The magnitudes of mean UACR change from baseline with saxagliptin were greater in the eGFR < 30 and 30–50 ml/min/1.73 m 2 subgroups at − 245.2 mg/g and − 105.0 mg/g, respectively, although in the former subgroup it did not reach statistical significance; a smaller but significant improvement in UACR (− 19.3 mg/g; P = 0.033) was observed in the eGFR > 50 ml/min/1.73 m 2 subgroup [ 58 ].

A cluster from SRT 82-184 ms showing the control curve higher than the PD curve also trended towards but did not reach statistical significance ( p = 0.034, cluster sum=105.67).

In addition, the SOFAS score showed a discernible trend suggesting a potential association with the number of training sessions, although it did not reach statistical significance after FDR correction ( β = 0.246, CI = [0.043, 0.448], p = 0.034, pFDR = 0.070).

In the PUFA-high group, compared to the CTRL and PUFA-low groups, there was a trend towards a lower freezing response to the new tone, although this data did not reach statistical significance (Kruskal-Wallis, H = 6.68; p = 0.035, Dunn’s post hoc: PUFA-high vs.

In the controlled T2D group, cortical thickness differences compared to CH without T2D did not reach statistical significance in any of the examined brain regions except for the left pericalcarine cortex (p = 0.036).

Through logistic analyses, we found that the association between serum lipid levels and the ORR did not reach statistical significance (Supplementary Table 1), but we found that LDL-C and non-HDL-C were reliable predictors of the DCR (HR: 16.309, 95% CI:1.207–220.326, p = 0.036; HR:34.484, 95% CI: 1.840–646.378, p = 0.018) (Supplementary Table 2).

Of note, the viral RNA load in the lungs of female mice was lower than that in male mice at comparable ages at 3 dpi, although the difference did not reach statistical significance except in 16-month-old mice ( p = 0.036) ( Figure 2B ).

Ruxolitinib treatment alone resulted in a 20% reduction in NHO volumes at day 7 and 35% at day 21, but this did not reach statistical significance by one-way ANOVA (significant by Mann-Whitney test at day 21 p = 0.037) ( Figures S6 C and S6D).

Considered individually, miR-320a-5p showed a statistically significant AUC score, while as miR-21-3p did not reach statistical significance (AUC = 0.647, p = 0.037 and AUC = 0.453, p = 0.058, respectively).

For mean reticulocyte volume ( n = 176 SNPs), the primary IVW estimate did not reach statistical significance; nevertheless, the pleiotropy-robust MR-Egger analysis detected a significant protective association (OR: 0.9985; 95% CI: 0.9972–0.9999; p = 0.038), collectively reinforcing the potential involvement of erythroid traits in MS pathogenesis.

Although the results of the log-rank analysis did not reach statistical significance, the Wilcoxon analysis showed that SCs therapy had a positive impact on survival during the early stage of follow-up (P = 0.038).

The patency rates for fistula failures presenting with stenosis were slightly better than those presenting with thrombosis, but they did not reach statistical significance (67% vs. 52% at 12 months; P = 0.038).

3.67%), the difference did not reach statistical significance ( p = 0.039).

Although the p -value for precision (0.098) did not reach statistical significance—likely due to limited sample size—the latency increase ( p = 0.0399, d = 1.43) was both statistically and practically significant.

While the specific toothbrushing time categories did not reach statistical significance among children aged 6–8 years, the overall timing of brushing showed a significant relationship with lower caries prevalence ( p = 0.04), indicating a possible cumulative effect across all examined categories.

MLR, lymphocyte count, E/e’ ratio, LA volume and diastolic dysfunction did not reach statistical significance ( p > 0.04) and were therefore not included in our ROC analysis.

Adverse events and procedure times were lower in the FTRD ® group, although these differences did not reach statistical significance (4.44% vs. 15.5%, p = 0.04 and 25.6 ± 10.6 min vs. 76.7 ± 26.4 min, p ≤ 0.01).

Subgroup analysis stratified by treatment regimen revealed that the same cutoff value predicted a trend toward longer survival in patients receiving combination therapy; however, the results did not reach statistical significance for OS (PFS: p = 0.04, OS: p = 0.06).

However, examination of the outer T cell-rich zone of mTLS showed higher mean densities of CD8 and PD-1 positive lymphocytes in the PT cases, although this did not reach statistical significance ( p = 0.040 and 0.029).

When depression severity was categorized as no depression, mild, moderate, and severe, a trend toward an increased incidence of stroke in the moderate and severe depression groups was observed; however, this trend did not reach statistical significance (p=0.04) ( Table 1 ).

Three studies assessed changes in femoral neck BMD, and the random-effects model showed an increasing trend (SMD = 0.24, 95% CI: −0.01–0.49), but this did not reach statistical significance, with moderate heterogeneity (I 2 = 70%, p = 0.04).

While there was a notable level of heterogeneity, it did not reach statistical significance ( I 2 = 97%, p = 0.04).

While this difference, and the presence of t(14;16) and deletion (17p), did not reach statistical significance, a higher number of patients in the early progression cohort had t(4:14) (21% vs. 8.9 %; P =0.04).

Response to lenzilumab was observed in the first through third quartiles of baseline CRP with the greatest lenzilumab treatment effect observed in the first quartile (CRP <41 mg/L; HR: 8.20; 95% CI 1.74 to 38.69; p=0.0079) and a numeric difference that did not reach statistical significance in the second quartile and a significant treatment effect observed in the third quartile (CRP 79<137 mg/L; HR: 2.25; 95% CI 1.04 to 4.88; p=0.0407 ( table 3 )).

Interestingly, flatulence sensation paralleled intestinal gas evacuation and reverted to the level before administration, but the other sensations remained above pre-ingestion level; the differences between late ingestion and pre- ingestion levels were small and did not reach statistical significance, except for abdominal discomfort ( p = 0.041).