“highly significant”

Using an Analysis of variance, we found highly significant differences ( p < 2.2 × 10 −16 ) and a non-parametric Wilcoxon Mann–Whitney test confirmed the significant differences of absolute Spearman correlation in healthy versus diseased samples ( p < 2.2 × 10 −16 ).

Indeed, pit-diggers performed ~ 15x more CNN-predicted scoops versus spits within daily bower ROIs and this pattern was highly significant within each subject (CV: 273 scoops vs. 20 spits, χ 2 = 311.35, p < 2.2 × 10 –16 ; TI subject 1: 339 scoops vs. 16 spits, χ 2 = 127.2, p < 2.2 × 10 –16 ; TI subject 2: 602 scoops vs. 60 spits, χ 2 = 377.28, p < 2.2 × 10 –16 ).

Pearson correlation analysis of these whole‐sample average expression profiles revealed highly significant correlations between replicates (Peach: r = 0.94, p < 2.2e‐16; Nectarine: r = 0.91, p < 2.2e‐16), with LOESS regression confirming the linear relationship (Figure S15A ).

glaberrima are ∼99.5% identical on average, the differences in sequence conservation between promoters and intergenic sequences are small, but the large sample size assures that they are highly significant ( P value <2.2E−16).

The 138 c-Jun-regulated genes showed a highly significant 5.8-fold enrichment (p=2.2×10 −16 ) among the 1581 genes regulated during chronic denervation.

The reversal DEGs obtained from the dataset for each cell type were highly significant, based on empirical null distribution (B cells: n=24, p-value <2.2×10 −16 ; CD4+ T cells: n=67, p-value <2.2×10 −16 ; CD8+ T cells: n=108, p-value <2.2×10 −16 ; monocytes: n=183, p-value <2.2×10 −16 ; NK cells: n=66, p-value <2.2×10 −16 ) ( supplementary figure S5a–e ).

For example, the Fisher exact test for association between the markers rs3856806 and rs41516544 for both males and females was highly significant (P-values <2.2×10 -16 and 1.102×10 -12 , respectively).

As expected, we observe an excess of sites with high values of -ln(PIP n ) in real data, whereas the number of sites that show a medium value of -ln(PIP n ) is higher for the simulated data; results are highly significant (Kolmogorov-Smirnov test, p < 2.2e -16 for both datasets).

In this study, we found a highly significant correlation between the letter and pseudo-letter versions of the MEP task ( r = 0.73, p < 2.2 × 10 −16 ; CI = 0.710–0.758; dis-attenuated correlation r = 0.915, with task reliability of 0.80).

The richness of species and genera were higher in the historic samples than in the recent samples, but proportions of endemic genera and species were lower in the historic samples ( table 2 ). Highly significant declines were documented both in the numbers of species ( p = 2.20 × 10 −16 ) and genera ( p = 1.13 × 10 −10 ) between the 1940s and the present ( table 1 ).

Notably, the relaxed (R) state showed highly significant differences ( p < 2.2 × 10 −16 ) from all other emotional states across all features.

2d and e ) and the Pearson correlation of these DNAm changes is highly significant ( p < 2.2 × 10 −16 ).

andersonii (tested via independent samples Wilcoxon rank-sum test), while its F is value was also significantly lower ( P < 0.05).Furthermore, verification of Rarefied Allelic Richness (Ar) via the Kruskal-Wallis rank sum test revealed a highly significant difference between the two species (chi-squared = 1770.3, df = 1, P < 2.2e-16), confirming that the genetic diversity of B. andersonii is robustly higher than that of B. tianguii even after standardizing sample sizes ( Figure 3 ). 3.3.

Averaging power in this range across the entire cue presentation period revealed a highly significant difference between the six regions in the 3-s spatial working memory task (F 5,1096 = 19.98, p = 2.2E-16, effect size: η 2 = 0.09).

Using a pairwise comparison of 5286 genes with adjP ≤ 0.1 for log fold change of WT MR versus WT Con and NRF2 KO MR versus NRF2 KO Con, the correlation of the effect of MR in the two genotypes was highly significant (R 2 = 0.64, p < 2.2 × 10 −16 , Supplementary Figure S2 ).

Additionally, a Kruskal-Wallis test revealed a highly significant difference in ANI across the three comparison types (χ2 = 6,332.9, df = 2, P < 2.2e – 16).

Although correlation is less than observed for the H3K4me3 replicates, many H3K4me3-positive loci are bound by TBP and the correlation is highly significant (r = 0.40, p<2.2 * 10 -16 ).

There was, however, a highly significant correlation between change in TE score and GC content (Pearson’s correlation value of −0.1337, p-value<2.2e −16 ) ( Figure 1I ).

On the other hand, when we considered each individual base count independently, we observed that the count of G nucleotides specifically shows a stronger negative correlation (R = −0.22) than the C nucleotide count (R = −0.074) alone ( Figure S5 A), although both correlations are highly significant (P < 2.2 × 10 −16 ).

This revealed a highly significant association between gene age and expression specificity in both species ( D. melanogaster : χ 2 = 1092.66, df = 5, p < 2.2 × 10 −16 ; A. aegypti : χ 2 = 890.74, df = 5, p < 2.2 × 10 −16 ), indicating that stage‐specific genes are significantly enriched for evolutionarily young genes. 2.4.

Comparing the probeset response slopes predicted by our model with the slopes obtained from the Affymetrix tissue panel data, we detected a highly significant correlation both in mouse and human (Pearson correlation coefficient in mouse 0.528, P << 2.2 × 10 −16 , and in human 0.468, P << 2.2 × 10 −16 ).

Somewhat surprisingly, we found a reasonably strong and highly significant correlation between these values ( R =–0.28, p<2.2e-16).

The difference in the location of the median for the success statistic distributions obtained using the two approaches was highly significant ( p < 2.2e‐16) for all three drugs and showed that the PopPK approach performed significantly better than a standard NCA approach.

Of these orthologs, 5,292 genes were located on the autosomes and 942 on the X chromosome, resulting in a highly significant difference in their chromosomal distribution (chi-squared test, p < 2.2 × 10−16).

Similarly, the prevalence of typhoid was notably elevated in Bumbu (91.3%) compared to Bandal (77.4%), with a highly significant X 2 result ( p < 2.2 × 10 −16 ).