The differences of the expression distributions between bound and unbound genes for all the transcription factors under study are highly significant (p-value<1e-15).
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picta as indicated by the highly significant logistic regression of male proportion against wCTUs (Z = −15.15, P < 1 × 10 −15 ) (Fig. 3c ).
The association between C/EBP δ mRNA expression and sensitivity to panobinostat is replicated in LC 2 from CTRPv2, with the pairwise relationship also being highly significant (Spearman ρ = −0.30, p < 1 × 10 −15 ).
A t -test between the UTR lengths in the “average fold-change” group and the “high fold-change” group was highly significant, with a p -value < 10 −15 .
Transcriptomic analysis of differentially expressed genes following cannabis or tobacco smoke exposure for 24 h at 10% dilution revealed a highly significant correlation ( r = 0.695, P < 1.0*10 −15 ) and overlap of shared changes in gene expression (Fig. 1 , n = 389, purple triangles).
This test was highly significant for all four types (charge, volume, polarity and Grantham distance) of coevolving groups ( p -values < 10 -15 ).
We observe a 8% depletion of fragile codons in single-exon genes that is highly significant ( p <10 −15 , Wilcoxon rank sum test; Table 1 ).
Interestingly, we found a highly significant overlap between genes repressed in daGAL4 > UAS-dInR DN and those activated upon removal of dfoxo in that genetic context ( P <10 −15 ), while the overlap between genes activated in daGAL4 > UAS-dInR DN and repressed upon dfoxo deletion was marginally significant ( P =0.01).
Chi-square analyses indicated highly significant associations (females p<10 −15 ; males p<10 −18 ) between experimental temperature and the percentages of rhythmic, weakly rhythmic, and arrhythmic adults.
2c and Supplementary Data 2 ); pairwise comparisons were likewise highly significant ( n = 398 and 753, respectively, both p < 10 –15 ; Supplementary Fig. 4 ).
Analysing the combined amino acid composition of the complete proteomes, we indeed find a small but statistically highly significant shift in ERK of endothermic compared to ectothermic vertebrates (Figure 3 ; Wilcoxon rank sum test: p < 10 -15 ).
This result was consistent across feature levels and parameter settings, and is highly significant for all tests: that is, for every comparison between modular subnetwork features and gene features, we have P < 10 -15 .
The overlap of DTA and DGE events identified across all three data sets was highly significant (phyper P < 1 × 10 −15 ), confirming the robustness of our findings.
Kruskal–Wallis H tests on statistical differences in the distributions between the baseline model and the full model are highly significant ( P < 1 e −15 ).
Similarly, we found slightly reduced but still highly significant correlations using expression differences normalized to the average variation (effect size) (Pearson's correlation R = 0.566, p < 10 -15 and R = 0.584, p < 10 -15 , respectively).
Highly significant linkage disequilibrium was found between the cream locus and SNP8 (LRT = 88.5, P < 10-15 ), SNP1 (LRT = 41.6, P < 10-10 ) and Del (LRT = 32.5, P < 10-8 ).
This association is highly significant ( p < 10 -15 ).
This is clear from gene ontology (GO) analysis of the genes associated with HOT regions: Categories such as ‘metabolic process’ and ‘cellular component biogenesis’ are highly significant (both P < 10 −15 ).
Our analysis of first round data indicates that while there was considerable diversity in the raw scores provided by individual participants, the inter-rater concordance was substantial and statistically highly significant (Kendall’s W=0.150, p-value < 10 −15 ).
We observed highly significant ( P < 1 × 10 −15 , binomial test) enrichment of conserved miRNA binding sites among genes that currently share experimental evidence for neural 3′ UTR extensions in both mouse and human ( Fig. 7B ; Supplemental Table S7).
This difference is highly significant ( p < 10 -15 , χ 2 -test, df = 1).
12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$\chi_{9}^{2} = 75 + 225 = 300$$\end{document} χ 9 2 = 75 + 225 = 300 , a highly significant test (P < 10 −15 ).
Comparing between a paper’s date of publication and its citation count reveals there is a low anti-correlation (−0.2) but highly significant between the two (Pearson product-moment correlation test P -value < 10 −15 , Supplementary Fig.
ANOVA indicated that the overall regression model was highly significant (F = 699, p < 1 × 10−15).
This module includes 44 DEGs, which is a highly significant enrichment (Fisher’s exact test, Odds ratio = 75.84, P < 10 −15 ).