“highly significant”

This module includes 44 DEGs, which is a highly significant enrichment (Fisher’s exact test, Odds ratio = 75.84, P < 10 −15 ).

The difference between means of A and B is highly significant ( P -value < 10 −15 ; two-sided Student's t -test).

In particular, the adjusted R 2 for the two fits in Figures 3A and 4C from [ 6 ], are respectively, 0.97 and 0.25, where F value (160) for the fit comparison is statistically highly significant (P~10 −15 ).

First, they represent a consistent and highly significant (Wilcoxon test P < 10 −15 in all growth phases except LS) decrease in expression across hundreds of rpoS regulated genes, in all five growth phases.

Results A highly significant variation among all individuals and within each breed was observed in the number of duplications ( P < 10 −15 ) and in the number of deletions ( P < 10 −15 ).

Our analysis of first round data indicates that while there was considerable diversity in the raw scores provided by individual participants, the inter-rater concordance was substantial and statistically highly significant (Kendall’s W=0.150, p-value < 10 −15 ).

Again, we found a highly significant overlap (Fig. 2 b), with 43.1% (401/931, p < 1.0 × 10 −15 ) of the HIV-responsive proteins identified here being part of the HHPID.

PPI networks identified by STRING analysis showed highly significant functional associations (PPI enrichment p -value < 1.0 -15 , for both γ-ray and X-ray irradiation response analyses).

Due to large sample sizes, all obtained P values for context/subcontext comparisons are highly significant ( P < 10 −15 ) for all observations mentioned in our study.

Application to the present data indicated that TT has a very highly significant effect on hit rate (p < 10 -15 ), as shown in Table 1 .

Scatter plots of the log2FC values for differentially expressed genes in the tetramer+ cells arising in response to each pMHCII-NP type confirmed highly significant correlations among the scRNAseq profiles of the different tetramer specificities (P<10 -15 ; >60% of all the genes in each comparison undergo similar levels of upregulation or downregulation as compared to Tconv cells) ( Figure 2C ).

1d ) fitted the standard logistic population growth model well and displayed highly significant increase in biomass ( p < 10 –15 , likelihood ratio test), which is typical for the growth of microorganisms under favorable conditions 23 .

All three pairwise within-individual differences between wake, NREM, and REM slopes were highly significant ( p < 10 −15 matched-pair t tests) and similar results were obtained for C3-M2 (Extended Data Figs. 1-2 , 1-3 ).

The baseline method ROTS that ignores longitudinal trends also performed well with an IQR mean pAUC of 0.941, while the difference to the best performing method RolDE was highly significant ( p < 10 −15 ).

Interestingly, we found a highly significant overlap between genes repressed in daGAL4 > UAS-dInR DN and those activated upon removal of dfoxo in that genetic context ( P <10 −15 ), while the overlap between genes activated in daGAL4 > UAS-dInR DN and repressed upon dfoxo deletion was marginally significant ( P =0.01).

These differences in substitution rates between exonic and AR sequences are highly significant ( P < 10 -15 , two-sided Mann-Whitney (MW) test) and are consistent with a fraction of the ncRNA exons having evolved under selective constraint.

Student's t-test analyses show highly significant differences in the overlap of p12 with chromosomes between mitotic and interphasic cells for the 1xMycR virus (p<10 −15 ); similarly highly significant differences in the overlap were observed amongst the 1xMycR or 1xMycR/PM14 viruses in mitotic cells (p<10 −17 ); and an absence of such differences for either the two viruses in interphasic cells or for the 1xMycR/PM14 in mitotic and interphasic cells (p>0.4).

This showed a highly significant increased risk of MS associated with smoking with no significant statistical heterogeneity (RR 1.48, 95% CI 1.35–1.63, p<10 −15 , heterogeneity: χ 2 = 7.38, p = 0.60; figure 1 ).

In the case of pairs corresponding to Cluster II, there was a clear inverse relationship between ω and t , with a highly significant statistical correlation ( r = -0.9032, P < 10 -15 ).

Chi-square analyses indicated highly significant associations (females p<10 −15 ; males p<10 −18 ) between experimental temperature and the percentages of rhythmic, weakly rhythmic, and arrhythmic adults.

In contrast, both adult studies showed highly significant (all P <10 −15 , matched-pair t -tests) reductions in spindle density (12% and 15% reductions in SHHS and MrOS, N =2,597 and 958, respectively), amplitude (5 and 12%) and duration (2 and 2%) across the ∼5-year period, consistent with the cross-sectional analyses.

This test was highly significant for all four types (charge, volume, polarity and Grantham distance) of coevolving groups ( p -values < 10 -15 ).

We observe a 8% depletion of fragile codons in single-exon genes that is highly significant ( p <10 −15 , Wilcoxon rank sum test; Table 1 ).

Likewise, it is intriguing that there is a highly significant overlap (p < 10E −16 , Fisher’s exact test) between the transcripts identified as PTZ stimulated, particularly those that are downregulated, and those described previously as bound to astrocyte ribosomes in perisynaptic fractions ( Sakers et al., 2017 ).

The 737 shared downregulated genes were enriched in GI pathways ( Figure 3E ), and this overlap was highly significant by hypergeometric test ( P < 1 × 10 –15 ; ~5-fold enrichment) ( 65 ).