“highly significant”

However, there was a highly significant interaction between these factors [ F (4, 48) = 6.97, p = 0.001, η 2 p = 0.37].

Data analysis Data analysis showed a highly significant association of JET and postoperative temporary third degree AV block ( P < 0.001).

The difference between the AI-first and ECP-first groups in the abnormal result scenario was highly significant ( β = 4.28, p < 0.001).

siamea , the differences in TF between treatments were highly significant ( p < 0.001, data not shown) with highest TF values compared to the other tree species.

All micronutrients displayed highly significant inter-site variation ( p < 0.001).

Previously reported data demonstrated a pronounced TP53-dependent differential response of HL cell lines to etoposide treatment: TP53-wildtype L-540 cells responded faster and more robustly than TP53-mutant L-428 cells with respect to reduced proliferation and viability, induction of apoptosis and necrosis (absent in L-428), accelerated nuclear fragmentation, and highly significant differential expression of apoptosis-related genes ( p < 0.001), including TP53, TNFα, HO1, and GADD45.

The omnibus difference remained highly significant (H = 170.7, p < 0.001, ε2 = 0.031), and the Q1–Q2 contrast — the study’s central finding — remained significant ( p = 0.003, r = 0.057), with Q1 retaining the lowest mean (rising from 7.52 to 7.73) and Q2 the highest (8.09).

Of 12,341 tests, 55.14% (6805) showed significant signals ( P < 0.05), with 34.7% (4281) being highly significant (|Z| > 3, P < 0.001) ( Fig. 4 A).

For all photochemical parameters, the main effect of dose was highly significant ( p ≤ 0.001), whereas neither sampling time (DAI) nor the Dose × DAI interaction showed significant effects, indicating that photochemical responses remained stable between 12 and 63 DAI.

Regarding biological characteristics, multiple births emerged as a highly significant risk factor, accounting for 4.3% of deaths, which is more than triple their prevalence among survivors ( P <0.001), while male sex showed a marginal association (56.3%, P =0.083).

Previous research has shown that all cross-scale correlations between corresponding OHQ and OHI items were highly significant (p < .001), and for most items, the correlations were strong. 30 The OHQ has been demonstrated to possess adequate construct validity and internal reliability, as well as satisfactory structural validity. 31 The WHOQOL-BREF is a shortened version of the World Health Organization Quality of Life Assessment (WHOQOL-100) designed to measure subjective quality of life across multiple life domains. 32 The measure assesses four key areas: physical health, psychological well-being, social relationships, and environmental health.

For between-group effects, Q was highly significant, (Q = 252.02, df = 31, p < .001, I 2 = 87.6%).

While, Lutz et al 18 reported highly significant ( P <0.001) reductions in bilateral hippocampal volume among FM patients; however, depressive symptomology was not explicitly controlled.

The two first-stage paths from digital orientation to Organizational learning ( β = 0.513, p < 0.001) and to Organizational forgetting ( β = 0.487, p < 0.001) were both highly significant, as were the second-stage paths from Organizational learning ( β = 0.276, p < 0.001) and Organizational forgetting ( β = 0.263, p < 0.001) to AI capability.

The overall performance on shape trials was highly significant (80 % correct, Chi-square test, n = 100, p < 0.001) with 76 % correct “same” responses ( n = 50, p < 0.001) and 84 % correct “different” responses ( n = 50, p < 0.001).

Snack consumption frequency showed a highly significant difference (χ2 = 19.79, p < 0.001), where 21.3% of females reported consuming snacks less than three times per week, compared to only 14.0% of males, indicating that females had comparatively healthier snack habits.

These agents produced highly significant reductions (* P < 0.001) from the early stages of treatment and maintained superior efficacy throughout the 28-day study period.

Overall differences in both FQ-R rates and the proportion of ST131 among FQ-R isolates across sources were highly significant ( P < 0.001).

The overall association remained highly significant ( P < 0.001), and the nonlinear test confirmed a pronounced nonlinear dose-response relationship ( P = 0.001).

There was highly significant differentiation among subspecies based on the mitochondrial data ( Φ ST = 0.773, P < 0.001, Table 3A ).

A two-way ANOVA (model × group) revealed a highly significant overall difference in classification accuracy among the models ( F = 1.795627 , p < 0.001 ).

All two‐way interactions were highly significant ( p < 0.001 for each), and the three‐way interaction (AgeGroup × Season × ROI) was also significant ( F 2,1092 = 4.02, p = 0.018). 3.3 Estimated Marginal Means The EMMEANS for all significant effects and interactions are presented in Tables 3 and S1 , and Figure 3 .

Although interaction between gender and aggression scores was highly significant [F = 10.991, p = 0.0010, η 2 = 0.014, power = 0.912], no gene-sex interaction was found (p = 0.8834).

Bartlett's Test of Sphericity was highly significant (p < .001) and the Kaiser-Meyer-Olkin (KMO) measure of sampling adequacy value of .9 supported the factorability of the matrix [ 21 ].

The overall RDA model was highly significant (permutation analysis P -value < 0.001) with five axes and 6.59% explanation of the total genetic variance (Fig. 2 D, E).