“highly significant”

In addition, statistical analysis showed highly significant differences between the BC SBR grading according to BCL2 expressions, indeed its rates among SBR grading ( Figure 3-A , p= 0.00168) showed high percentage in SBR I.

Moreover, 68 PSGs were both down-regulated in the long-lived naked mole-rat and up-regulated in the short-lived rat during aging ( Fig 2 ), resulting in a highly significant preference for quadrant I (down in naked mole-rat, up in rat; p = 0.0017, one-sided fisher test, quadrant I against the sum of II, III, IV).

We found that, in the BAC region of overlap across the two dosage levels (0–0.025%), as expected, linear regression revealed a large and highly significant elevation in the y ‐intercept estimate for the lower‐dose condition (Δ = +15.6%, F 1,23 = 12.67, P = 0.0017).

The independent variables that we identified in the univariate analysis in GC + DU cases were D58, D58/K59, D58/K59/Q62, and D58/K59/I60/Q62 and DKIGQ polymorphisms with age and gender were included and only D58/K59 was determined as highly significant (OR: 6.5, P = . 0017) ( Table 8 ).

Interestingly, there was a highly significant positive correlation ( r = 0.7575, P = 0.0017) between GHSR1a and ghrelin ( Fig. 5A ) and also between GHSR1a and SERCA2a ( r = 0.7154, P = 0.0040) ( Fig. 5C ).

g ba −/− immortalized neurons showed a severe deficiency in enzyme activity (3.40±0.36% relative GCase activity, mean±s.e.m.) compared with gba +/+ immortalized neurons (93.44±12.26% relative GCase activity), which was highly significant ( P =0.0017) ( Fig. 3 C).

Moreover, significant changes were observed in several parameters: the proportion of subjects with FVC < 80% showed a highly significant decrease ( p = 0.0017).

2 B); this association was highly significant (correlation between GABA and average normalized suppression indices r = 0.88, p = 0.0017).

A linear correlation was highly significant between the measurements of conidial hydrophobicity and adherence from the tested strains (r 2 = 0.975, F 1,19 = 116.7, p < 0.0017).

There was a highly significant difference in CN between the three conditions tested for all samples (Friedman test p = 0.0017 for EIF2C1 and 0.0046 for TSC2 ), with a significant pairwise difference between the original and Puregene CN values after Dunn’s multiple comparison correction (p = 0.0045 and 0.0141 respectively).

In a multivariate regression analysis, utilizing baseline CA19-9, and baseline ctDNA KRAS as continuous variables, along with the co-variates of interest, stage, gender (sex), and baseline European Cooperative Oncology Group (ECOG) performance score, ctDNA KRAS remained highly significant for TTP (HR = 1.45; 95% CI 1.15–1.83, p = 0.0017), while baseline CA19-9 was less significant (HR = 1.27; 95% CI 1.03–1.58, p = 0.0284) along with sex (HR = 0.79; 95% CI 0.63–0.99, p = 0.0400) (Table 3 ).

Due to a 3- to 4-fold upregulation of CASQ2 4 weeks after TAC, this difference is not significant by 2-way ANOVA, but highly significant by Student’s t-test (p = 0.0017).

Primary outcome (secondary hyperalgesia areas) Baseline data Data consistency during Session 1 vs Session 2 ( Figure 2B ) was examined by ICC’s (0.85 [0.64–0.94]) and by comparisons of baseline assessments using simple paired sample tests demonstrating a highly significant difference in baseline assessments between the sessions (Wilcoxon: P =0.0017).

The pseudo-absence selection method had a highly significant (ANOVA, p = 0.0017) effect on model mean AUC values, but the interaction between model type and selection method was insignificant.

As expected from the definition of the 0.1% threshold, it was highly significant to discriminate PFS between both groups of patients (Figure 3 , p = 0.0017) and although OS was better for the HFLC‐low group, the difference was not statistically significant.

The log-rank statistic comparing the survival times of the first subtype and the third subtype (as shown in Figure 1 ) shows highly significant differences ( p = 0.0017).

Kaplan–Meier survival performed on all IHC subgroups revealed that an overall log-rank test was highly significant for both PFS ( p = 0.0017, Figure 3 B left) and SOS ( p = 0.0081, Figure 3 B right).

The difference between the X and the other KTs was highly significant (p < 0.0017, t test).

0.08), highly significant in univariate ( p = 0.0017) and multivariate ( p = 0.014) analyses.

The difference was highly significant ( P = 0.0017) as determined using the Mann–Whitney non-parametric statistical method.

Similarly a highly significant correlation between incidence of CD and lactase persistence (r = -0.655, p = 0.0017) was reported in an observational study encompassing data from 20 countries [ 19 ], whilst Shrier et al [ 20 ] reported a reduction in CD risk with increasing prevalence of lactase non-persistence in a review of global population data.

Enzyme-linked immunosorbent assays determined highly significant differences between apocrine-dominant sweat (AP), saliva before exercise (SBE), and saliva after exercise (SAE) cortisol concentration (AP-SBE: p = 0.0017, AP-SAE: p = 0.0102).

However, such difference (30 and 33 vs 0%) in the number of clones undergoing mitotic catastrophe between CD9- and vector-transfected PC-3 cells is highly significant ( P =0.0017).

Three and four month in-situ explants had highly significant differences in failure load between measurements close and distant to the osteotomy line: p=0.0017 (the region of maximum load in-situ ).

Conversely, as expected for a protein-coding gene evolving under selective constraints, the substitutions attributed to the genuine mitochondrial lineage showed a highly significant codon position bias ( χ 2 = 12.72, df = 2, p = 0.0017), in which mutations at the third codon position were overrepresented (94 versus 74.5).