For the lowest dose of VSV-G pseudotyped HIV-1 (0.2 ng of p24 antigen/placental fragment), the effect of TNF-α on the viral replication was highly significant with a mR of 4.59 ± 0.91 (p = 0.002) after 120 hours postinfection and was not observed at earlier time points with a mR of 1.04 and 1.01 after 48 and 96 h, respectively (Figure 2A ).
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As shown in Figure 3 , in a PAR 2 -LRP6 co-transfected cells, SLIGKV peptide activationfor 5 min induces a highly significant ( p =0.002) maximal increment in BRET ratio.
T-tests on changes from baseline show that, at all time points throughout the study, the HDL/TC improvement from baseline was highly significant (p < 0.002).
We observed a highly significant effect of “sleep stage” (F 2,144 = 6.49; P = 0.002) and a near significant effect of “frequency band” (F 7,72 = 2.13; P = 0.051), but no effect of “locus” and no interaction.
Overall, 29/149 (19.5%) patients responded with ≥75% seizure suppression in the non-SV2A group compared with 14/175 (8%) patients in the SV2A group, a highly significant difference ( P = 0.0020; Fisher’s exact test).
The difference in the net rate of cladogenesis is highly significant (likelihood ratio test = 6.381, d.f. = 2, p = 0.002).
A correlation test was thus performed between Kmax and the eye movement parameter, revealing a highly significant association between Kmax and the number of eye movements (Kendall’s Tau–B, 0.440, p = 0.002) (Fig. 1 ).
PG545, respectively) ( Figure 3 C , upper panel), differences that are statistically highly significant ( P = .002).
By contrast, there was a highly significant difference (P = 0.002) in survival favouring patients weighing less than or equal to 60 kg compared with those weighing greater than 60 kg.
The mean plaque index at 6 months, the comparison between Group A and Group C showed a highly significant mean difference of −0.70667 ( P = 0.002), underscoring the most substantial reduction in PI in Group A over time.
The significant interaction reflects that there was no significant difference between the reporting of the two modified motif types in the unfamiliar condition (p = 0.452, average response latencies for discriminating gap and noise motifs from the from the background of complete motifs were 1002 and 955 ms, respectively), whereas there was a highly significant difference in the response latencies for reporting the two modified motif types in the familiar condition (p = 0.002, average response latencies for discriminating gap and noise motifs from the from the background of complete motifs were 1219 and 1478 ms, respectively).
This may seem quite a low value, however it should be noted that the distance varies from 0 to 380 (see Table 2 ), so the highly significant relation ( p = 0.002) will vary in this range.
Head-butting is found to have a highly significant statistical effect on reconstructed head posture (F = 39.467; p-value = 0.002), with a difference of 13° between head-butting and non-head-butting species on average (Fig. 7 ); however, with only 1° difference on average (Fig. 7 ), the same is not true for the neutral head posture (F = 3.126; p-value = 0.591).
We found highly significant (p< 0.002) evidence for neuronal damage in the cortex, hippocampus, and basal ganglia in the brains of exposed rats. status released display-pdf yes is-olf no is-manuscript no is-preprint no is-journal-matter no is-scanned no is-retracted no Full Text The Full Text of this article is available as a PDF (340.2 KB).
Both unadjusted and adjusted models demonstrated highly significant nonlinear relationships (unadjusted: overall P = .002, nonlinearity P = .004; adjusted: overall P = .002, nonlinearity P = .002), indicating that the impact of SHR on prognosis is not linear but increases sharply beyond a threshold of 1.215.
Correspondingly there was a highly significant interaction between temperature and ozone for both PAI-1 ( p = 0.002) and plasminogen ( p = 0.001) in our model.
These trends in IS and SWS were not significant, but as per above this was due to the low TST in the first hour of night: when this hour was omitted, there was a highly significant linear decrease in both IS (slope = -4.90 s/hour of night, r 2 = 0.732, p = 0.002) and SWS (slope = −7.66 s/hour of night, r 2 = 0.753, p = 0.001).
Statistical analysis revealed a highly significant difference in AUC between the Multi-score model and the other three models (P<0.002).
For the species analysis along with the explanatory variables the unrestricted Monte Carlo permutation tests (499 permutations) of the significance of the canonical axes indicate axis 1 as statistically highly significant (p = 0.002).
In particular, a strong and highly significant correlation was found for samples from the North Region (n = 8, R 2 = 0.751, p < 0.002).
Weight and SMA loss significantly increased over time, with a highly significant difference between the mean percentages of SMA at C3 and weight loss ( F = 10.99 [df=1], p = 0.002).
Two-way repeated measures ANOVA analysis revealed a highly significant increase in total plasma cell frequency ( Figure 1F ) associated with both IL-21 treatment (p=0.002, F=14.1) and KSHV infection (p=0.002, F=14.4) with a significant interaction of the two variables (p=0.001, F=17.8), indicating that KSHV and IL-21 synergistically increase total plasma cell numbers in our ex vivo cultures ( Figure 1G ).
These differences between the slower versus faster speeds were highly significant (P < 0.002 for On- and P < 0.001 for Off-responses, paired t test).
By excluding level six from the scoring, a highly significant difference between the groups was observed (U = 122.5, Z = 3.01, P = 0.002, r = 0.41).
In responding patients HS1 variations before and after therapy, measured with a Paired Student’s t -test, was highly significant (western blotting p = 0.002 and Real-Time PCR p = 0.001) while in non responding patients the variation before and after therapy was significant only in Real-Time PCR (p = 0.024, western blotting p = 0.067) probably because of the little number of non responding patients.