“highly significant”

The mRNA for Ch12, ORF39 (Spexin) demonstrated a highly significant 14.9-fold drop in expression in obese compared to non-obese fat tissues ( Figure 1B ), the largest change in gene expression observed in obese human fat (p=0.00292).

AD1) is highly significant ( P = 0.00298).

A highly significant hearing disturbance was detected around 24 kHz (42.1 ± 9.1 in +/+ vs. 74.3 ± 8.4 dB in −/− , p < 0.003, Fig. 1 A).

A highly significant difference could also be seen in the total score for each MM subgroup according to our scoring system ( P = 0.003) (Fig 2 ).

The total number of integron-positive isolates in diarrheagenic cases and healthy controls among EPEC and non-EPEC isolates were also found to be highly significant ( p = 0.003 and 0.011 respectively) as shown in Table 2 .

The mRNA expression levels of ChREBP and PPARα were highly significant in the interaction effects of exposure time and salinity ( F = 4.178, p = 0.003; F = 10.955, p = 0.000).

All the differences were highly significant ( P < 0.003) when the first 6 months of the study were compared with the 6-month adherence measurements evaluated during the entire period.

However, while pregnancy was associated with a highly significant fall in creatinine and rise in GFR in HbAA women (P<0.003, P<0.0001), neither occurred in HbSS women (P>0.5, P = 0.186 respectively).

A highly significant, positive correlation of these two parameters was also identified (Pearson correlation coefficient = 0.954; P = 0.003).

In obese participants undertaking a weight-control intervention, weight reduction reduced peak knee load and pain [ 32 ], and provided symptomatic relief, irrespective of structural damage [ 36 ]. Datasets from the Osteoarthritis Initiative and the Multicentre Osteoarthritis Study demonstrate a highly significant ( P < 0.003) dose–response relationship between weight change and improvement in WOMAC pain and function [ 37 ].

AVCMF (181/276 relapsed; control (199/263 relapsed); X2, = 11.68; P= 0.006. Prolongation of relapse-free survival was highly significant in premenopausal patients (X2i = 8.8; P = 0.003: Figure 2a) but of only borderline significance in post-menopausal patients (X21 = 3.3; P = 0.07: Figure 2b).

As shown in Table 2 , high WTAP expression was identified in 44.7% (84/188) of cases with tumors larger than 2 cm and in 28.9% (46/159) of tumors ≤ 2 cm; the between-group difference was highly significant ( P = 0.003).

In our results, the ready availability of water showed a highly significant relationship with the cost of illness at (p < 0.003).

ANOVA on MEPi recorded with the lower TMS intensity (120% rMT) revealed a significant main effect of Space ( F 1,11 = 5.81, p <.04) and Time ( F 3,33 = 5.05, p <.01) and most importantly, a highly significant Space × Delay interaction ( F 3,33 = 7.56, p <.003; see Figure 2A ).

A test for linear trend was highly significant, p = 0.003.

4 b), and a strong, highly significant negative correlation between peak firing rate and swap frequency (r = −0.41, p = 0.003; Fig. 4 c).

The overall model was highly significant (N = 14, R 2 = 0.650, P = 0.003), and the resulting equation was: heart rate (Hz) = 9.425+3.325*wingtip shape (C 2 , higher values indicate more rounded wingtips [3] )+0.002*wingloading (gm −2 ).

Results: Among 1000 subjects in rural and urban population highly significant difference was observed for Oral hygiene aids ( P < 0.003) and for DMFT ( P < 0.008) and no significant difference for dmft ( P > 0.26).

2 ), while this was true for only 10/50 (20%) of the patients in the CD-Ref group, representing a highly significant difference ( P = 0.003).

Comparing the time spent in the side chambers within each genotype revealed a highly significant difference for both the WT group and the Thy1-aSyn group ( p = 0.003), indicating that both WT and Thy1-aSyn mice at this age have a strong preference for a conspecific over an inanimate object.

As for precipitation, the addition of late period temperature renders early period temperature non-significant, with predictor weight of only 0.53, as compared to late period temperature which is both highly significant (p = 0.003) and has a high predictor weight (0.98) (Table 2 ).

When the median pSTAT-5 ratio (post/pre DC vaccination) in CD3 + CD8 + T cells was used to dichotomize patients, a highly significant difference in survival was observed (p = 0.003, Log-rank test).

The difference between the two competitive indices was highly significant (p<0.003).

Five SNPs, rs12495941, rs2339298, rs17244777, rs12051272, and rs12922394 located on ADIPOQ, RYR3, LOC101928392, CDH13, and CDH13, respectively, showed highly significant associations with plasma APN ( p = 0.003, 0.005, 0.027, <0.001, and 0.002, respectively).

A survival curve of the combined ICM groups partitioned by an R2I2 value of 1.03 is shown in Figure 7 ; a highly significant difference ( P =0.003, log rank) was observed.