“highly significant”

Detailed analysis of the palmitoylomics results revealed that knockdown of ZDHHC21 provoked a strong (approximately four-fold change plotted in log 2 scale, which correspond to approximately 15 times decrease in the palmitoylation level) and highly significant ( P = 0.0028) decrease of 5-HT1AR palmitoylation in comparison to the scr samples (Fig. 5h ).

Statistical analysis revealed highly significant reductions in expression levels ( p < 0.0028 for OmpA and p < 0.0001 for Bap ), demonstrating that the combination affects biofilm formation at the transcriptional level.

The differences in slope at higher I for the low R region of the PFR are highly significant ( t (75) = 3.23, p = 0.0028).

A stratified analysis by ethnicity revealed striking differences between Fulani and non-Fulani, with a very high and highly significant heritability estimate in the 135 Fulani (h 2 =0·71, P = 0·0028, likelihood ratio test) and a near zero and nonsignificant one in the 285 non-Fulani (h 2 =0·01, P = 0·49, likelihood ratio test) ( Figure 4 a).

For our peak-performing configuration, the acoustic + wav2vec 2.0 + WavLM fusion model post-exercise, we obtained highly significant empirical p -values of p = 0.00280 for the vowel phonation task and p = 0.00300 for the voluntary cough task, indicating that these results are statistically robust.

In addition, a highly significant correlation between plasma Cu, but not Zn or Cu/Zn ratio, and anti- Leishmania IgG was observed across patient groups (Fig. 2 , Spearman r = 0.65, p = 0.0028).

Intriguingly, the amount of protein carbonylation in the different lysate preparations showed a highly significant linear correlation with the percentage of long-term surviving mice (R 2 = 0.96, p = 0.0028, Fig. 5C ).

Association between fetal IUGR and fetal malperfusion appear highly significant ( χ 2 = 8.97, p -value = 0.0028) underlying the crucial role of placental disorders in fetal growth defects due to chronic fetal hypoxia.

carinatus, too, revealed highly significant differences (Kruskal–Wallis χ2 = 11.72, df = 3, p < 0.0028).

PRRX1 exhibited one highly significant correlation with TMEM33 ( r = − 1.000, p = 0.0028), while SLAIN2 showed significant positive correlations with PTPN2 ( r = 0.886, p = 0.033) and TMEM33 ( r = 0.943, p = 0.017).

With a median follow-up of 9.6 years, a highly significant decrease ( p = 0.0028) in the probability of LR was seen in the EBRT group, but no difference in OS was shown.

Linear regression analysis identified a highly significant increase of 26% in the average performance score that could be attributed to use of the checklist ( p = 0.00284).

The mediation analysis, assessed through the Sobel test, yielded a highly significant z-value of 298.406 ( p = 0.002845), confirming the statistical significance of the mediation effect.

While by Two-way RM ANOVA only the 700 ms interval was statistically significant, a Kolmogorov-Smirnov test demonstrated a highly significant difference in cumulative distributions, p = 0.0029). 3.4.

Intriguingly, dNP+ animals traveled significantly more than both PBS and sham animals, and this effect was highly significant ( p < 0.0029 dNP+ vs. sham, p < 0.0006 dNP+ vs.

This effect was highly significant across the population; locomotion significantly reduced the amplitude of phasic responses (p = 0.0029 with 4 Hz stimulation [ Figure 4 C] and p = 0.00033 with all stimulation protocols [ Figure 4 D]).

The results for the second variant under investigation (rs1470579) demonstrated that the CC genotype was more frequent in the patients' group (9.4%) than the control group (4.3%), with the statistical analysis displaying a highly significant difference ( p = 0.0029) between the frequencies of the C allele in the patients' group (25.3%) and control group (16.8%), as reported in Table 6 and Figure 5 .

Kaplan-Meier curves for overall survival showed highly significant differences in patients with remission (R), and no change (NC) or progression (P) at time of staging investigations after the third therapy cycle (p < 0.0029 between R and NC; p < 0.0001 between R and P; Figure 1A ) with median survival times of 528 (R), 328 (NC), and 327 (P) days, respectively.

Unexpectedly, while there were no significant interactions between genotype and sex after correcting for multiple comparisons, there were highly significant effects of sex on these DTI metrics in each region where FA (Supplementary Fig. 4A ; LM, p = 0.0029, p = 5.25 × 10 −5 , p = 7.71 × 10 −4 ), MD (Supplementary Fig. 4B ; Tukey HSD, p adj . 2.83 × 10 −10 ), and RD parameters (Supplementary Fig. 4C ; LM, p = 4.04 × 10 −9 and Tukey HSD, p adj . < 1.0 × 10 −20 ) were all higher in the males.

6A ), but a highly significant increase in the avidity index of anti-(NANP) 6 antibody ( p = 0.0029, Fig. 6B ) resulting from the inclusion of the tt epitope with (NANP) 3 , compared to (NANP) 3 alone, presented on Qβ.

This association is highly significant since the 10 isolated HSCR patients have only one variant but the 8 HSCR cases with additional anomalies have 7 variants (P = 0.0029).

Despite fewer wells with intact provirues, differences in the mean number of intact and defective proviruses per well remained highly significant (P=0.0029 to P<0.0001 by unpaired t test with Welch’s correction for intact proviruses vs proviruses with hypermutation and/or 3’ deletions).

This was not a significant change for the ischaemic stroke patients ( p = 0.109); however, for the haemorrhagic stroke patients, this reduction of the purine levels over 24 h was highly significant ( p = 0.0029).

We speculate that while our model shows a highly significant distinction between patients with a high or low risk of developing recurrence ( P = 0.0029, Fig. 3B ), the sensitivity and NPV of our and similar methods will not be sufficient to ethically withhold adjuvant therapy in the clinical application of a postoperative MRD‐test in stage II–III NSCLC.

Notably, the SE@95SP difference between EVA2 and Danp was highly significant (p ≈ 0.0029), as was the HLA difference between DC-LS and Danp (p ≈ 0.0065).