trachomatis infection at multiple time points ( Table S2 ), and linear modeling of log 2 [IFNα2] with SNP and 70 h post-infection burden as covariates revealed the SNP effect was much larger (regression coefficient = −0.623 versus 0.017 for burden) and was highly significant, with a p value of 1.87 × 10 −13 (versus p = 0.003 for burden) ( Table S3 ).
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The study was stopped prematurely by the data safety monitoring board because of a highly significant (p = 0.003) 43% reduction in stroke by the calcium channel blocker.
Linear regression analysis shows that this trend is highly significant for each group, and the magnitude of that drop is also similar for each group: for controls the change in temperatures was −0.173 °C/day (p = 0.003); for doxorubicin −0.274 °C/day (p < 0.001), and for ICT-2552 −0.199 °C/day (p = 0.005).
A highly significant impact on EFS was confirmed for Ph-like (hazard ratio (HR)=2·93, p -value=0·003) as well as for assignment to final High-Risk group (HR=2·25, p -value=0·03), while age and WBC at diagnosis did not have a significant impact on outcome ( Table 2 ).
48% of subjects who rated their health as very good or excellent exercised regularly, while it was a much smaller percentage in the "poorer" group (5.6%), with an OR of 15.69 which was highly significant (p = 0.003).
This difference in the enhancer was highly significant as assessed both by a Mann–Whitney test ( p = 0.003) and by a permutation test (200 permutations, p < 0.005).
The number of infants in Group 2 was statistically highly significant ( P = 0.003).
The increase was highly significant (from 40% to 80%) for G. mellonella ( P = 0.003), but not statistically significant (from 20% to 30%) for A. orientalis ( P = 0.552).
A simple Kendall rank correlation between RDA1 and the numbers of species was also highly significant ( p = 0.003).
The female had no significant effect (F 1,79 = 2.34, p = 0.130), but there was a highly significant effect of the male × female interaction (F 1,79 = 9.52, p = 0.003), because interspecific matings were shorter.
Multivariate RDA analysis showed highly significant differences in microbiota composition at a phylum level ( P = 0.003) between the 4 groups with no significant difference by Salmonella ( P = 0.263) but with a significant effect of OA blend as a factor ( P = 0.014).
While using the Cochran–Mantel–Haenszel test, which analyzes the correlation between the variables, the correlation appears highly significant (p = 0.003).
The difference in H o among the populations from the three zones was highly significant ( P = 0.003), as were differences for F is ( P = 0.002) and R elc ( P = 0.005).
This is also reflected on the distribution of genotypes across ACE I/D which is highly significant in a G-like test (P < 0.003).
After binarizing data (large values = 1, small values = 0), run tests showed near-significant ( Z = 1.772, p = 0.076) deviation from randomness for gene length and haplotype diversity, while nucleotide diversity displayed highly significant deviation ( Z = 2.938, p = 0.003), revealing a near-perfect “small-large-small-large” periodicity.
A correlation between the percentage of CD33 on primary blasts and NK effector functions appeared to be highly significant ( p = 0.003) for NK cell degranulation (CD107a).
Results showed highly significant differences ( t (18) = 3.50; p = 0.003; d = 0.80) for the present study and for the study of Denk et al.
The difference was highly significant between non-infected women and those with infection at the first trimester ( P = 0.003), while there were no differences when non-infected women were compared with infected ones occurring in the second and third trimesters (Fig. 4 C).
The post-intervention program revealed a highly significant improvement (with a highly significant difference, p < 0.003) in HbA1c post-intervention levels, which showed a significant improvement among the study group compared to the control group.
parapsilosis isolates from RTT subjects induced highly significant levels of IL-10 compared to HC C. parapsilosis isolates and RTT C. albicans isolates ( p < 0.003, Wilcoxon rank-sum test; Fig. 3 ) suggesting an increased fungal tolerance towards these C. parapsilosis isolates, potentially favouring fungal persistence within the host.
Twenty-five (41.7%) students and 10 (16.7%) villagers judiciously used their prescribed antibiotics ( Table 3 ), the difference of which was highly significant (p=0.003).
Interactions between sex and the age components transformed in the spline basis were introduced but only the parameter for the interaction with the third component was highly significant ( p- value = .003) and was retained in the final model (denoted by γ i ).
The difference of difference in face response rate with upright and inverted orientation (calculated for each SZ and TD participant) was highly significant (SZ, 0.10 ± 0.09; Mdn, 0.09, 95% CI [0.06; 0.14]; TD, 0.31 ± 0.25; Mdn, 0.21, 95% CI [0.2; 0.42]; Mann–Whitney test, U = 114.5, p = 0.003, two-tailed; η 2 = 0.204; Fig. 4 ).
Further analysis of these trends of the vehicle- and RTL342M-treated mice on day 63 demonstrated highly significant correlations between the clinical vs. histological data, with more damage ( p < 0.003), demyelination ( p < 0.01), and lower axon counts ( p < 0.001) with increased CDIs (Fig. 1c ), lending histological support to the improved clinical outcome observed in five of six RTL342M-treated mice.
To support this hypothesis, we explored the correlation between trNK and CD8 T infiltration in our murine orthotopic tumor model and found a highly significant positive association (R2=0.6571, p=0.003), which was strengthened when we focused on untreated (Mock) vs IR+IT combinations where trNK cells are evident (R2=0.9223, p=0.0004) ( Figure 6F ).