Overnight co-culture with progesterone (24 h) induced a highly significant reduction in NK cell cytotoxicity of tumor targets at differing concentrations (10 μM vs. 0.1 μM progesterone; n = 13; p = 0.0038; Figure 1 f).
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This was highly significant ( p = 0.0038).
The p-value (calculated by using the Chi-squared test and taking controls as a reference) for each study group was highly significant for type II (PCOD) anovulatory disorder (p < 0.0038) and type III anovulatory disorder (p < 0.0058).
Correlation among the serum DPP-4 activity, liver tests and HOMA2-IR in NAFLD Highly significant correlations were detected among the serum DPP-4 activity and ALT (r = 0.4637 p = 0.0038) and γGT (r = 0.4991, p = 0.0017) values in 39 patients with NAFLD.
In this study, vacuum therapy reduced WC from 42% to 21,4% also on the lower extremity, which was highly significant ( p = 0,0038).
The differences in the G-to-A mutation frequency between viral DNA and cRNA were highly significant ( P = 0.0038 and P = 0.0139 for Rounds 2 and 3, respectively; Student's t -test).
This enrichment is highly significant ( P = 0.0039 and P < 10 −15 for Illumina and Affymetrix, respectively).
However, at 3 times the recommended dose (90 IJs/cm 2 ) snail mortality (8.9%) was highly significant compared to the snail only control (p < 0.0039) ( Fig 5 ).
Consequently, this relatively large number of overtargeted genes was also highly significant ( P = 0.0039, as empirically determined by comparison to 10000 simulated equivalent random networks).
This difference was highly significant ( U 0.05(2), 6,6 = 0.00, P = 0.0039).
We observed a highly significant reduction in the concentration of 18-HEPE levels in paired coronary venous compared with aortic samples ( p = 0.0039) ( Fig. 1 , panel A), suggesting uptake and utilization of 18-HEPE by myocardium.
Fusion time was also identified as a highly significant factor ( P -value = 0.0039).
The low frequency of scores greater than 0.5 indicate that a score of 0.547 for gene pair ATG5/GLUT1 is highly significant ( p =0.0039).
The analysis of variance showed a significant difference between the presence of the virulence factors of a species ( p < 0.0173) and a highly significant difference between the species and the virulence genes ( p < 0.0039). 3.7.
Highly significant protection of vaccinated animals from BPV2-associated tumor formation was achieved ( p = 0.0039).
This difference in HHV-8 seroprevalence between the three disease groups was statistically highly significant (χ 2 = 8.35, p = 0.0039) [Table 3 ].
Compared to AX2, 80% of transformants containing mutated HTRA2 displayed slower plaque expansion rates and the plaque expansion rates reduced with increasing HTRA2 S300A expression levels (regression of plaque expansion rate against pPROF692 (HTRA 2S300A ) copy numbers highly significant: p = 0.00396, F test, n = 11).
2010 , 2011 ), preserving the RD lengths and positions and randomizing the positions of the RT asynchronous regions, we found a highly significant overlap as compared to what is expected by chance ( P -value = 0.003984).
Urine sodium of 130 mmol/L or greater was the most highly significant predictor of nonresponse to FR (OR 15.0; 95% CI, 2.4-95.8; P = .004) and while the closely-related Fürst ratio greater than 1 also predicted nonresponse, it performed less well (OR 2.7; 95% CI, 1.0-7.6; P = .05).
In Mossi ethnic group we noted that the CD3 + Panγδ + proportion remains stable through the season, whereas in Fulani ethnic group the proportion of these cells was double of that measured in Mossi ethnic group at the low transmission season and this difference was highly significant ( p = 0.004) (Figure 5 ) and remained significant during the high transmission season ( p = 0.04).
With the 10 6 PFU dose, the difference in weight loss of NZW/Lac mice relative to C57BL/6 was highly significant ( p <0.004) each day from 8 onwards; for C58 mice the difference from C57BL/6 was significant each day from 4 through 12 ( p =0.001–0.04).
Moreover, the correlation between TM4SF1 and patient survival was analyzed in 109 patients, and the Kaplan–Meier survival curve of low versus high expression of TM4SF1 showed a highly significant separation (Fig. 1E , P = 0.004).
This is a highly significant difference as determined by the chi-square test ( p = 0.004).
TT/TC: adjusted OR = 0.71, 95% CI = 0.56–0.90) in all subjects, and this result remained highly significant after Bonferroni’s correction for multiple testing ( P =0.004).
For cells from naïve animals tested with E GABA = -35 mV, 4-AP increased the proportion exhibiting PAD-induced spiking but not significantly ( p = 0.079; Fisher’s exact test) whereas the 4-AP effect was highly significant for E GABA = -20 mV ( p = 0.004).