“highly significant”

Similarly, nationality had a highly significant association with HCV infection (p=0.004).

This effect was highly significant (p = 0.004).

Molecular assay As shown in Figure 7a , AOM induced colon cancer group showed highly significant increase (P=0.004) in level of TP 53 gene expression as compared to control group.

The effect remained highly significant also when illusion strengths were corrected by subtracting the bias measured for the control stimuli (small: ρ = 0.4, p = 0.004, [0.14, 0.61]; large: ρ = 0.39, p = 0.005, [0.11, 0.61]).

5d clearly shows that our model captures the described observed relationship between the large-scale circulation anomaly and rainfall over Pakistan, with the correlation of r = -0.39 being highly significant ( p = 0.004 ).

This change was small (2.5±0.4%, n = 27), but highly significant (p<0.004; Fig. 4A ).

Pairwise comparisons show that the difference between onlookers and participants is highly significant in the train scenario, χ 2 (1, 400) = 8.51, p = 0.004, φ c = 0.146, and the large game show scenario, χ 2 (1, 419) = 6.33, p = 0.012, φ c = 0.123, but narrowly failed to reach conventional levels of significance in the small game show scenario: χ 2 (1, 365) = 3.38, p = 0.066, φ c = 0.096.

Of interest, pathway analysis based on both plasma metabolites and gene transcriptome demonstrated highly significant ( P < 0.004) differences of PPAR pathway between I − and I + T1D/ND participants.

To determine whether the accumulation of platinum was related to hydrophobicity, log P was correlated with platinum concentration- time products in neurological tissues, blood and plasma (Figure 3). Highly significant inverse correlations were found between log P and platinum concentration-time products in DRG (r2 = 0.99; P = 0.004), sural nerve (r2 = 0.85; P = 0.025), sciatic nerve (r2 = 0.98; P = 0.0012), brain (r2 = 0.98, P = 0.0011) and spinal cord (r2 = 0.97; P = 0.0018).

The data exhibited a highly significant negative direct effect of the DT intervention on IC (β = −0.373, p = 0.004, 95% CI [−0.618, −0.119]), alongside a significant positive indirect effect via AC (β = 0.083, p = 0.048, 95% CI [0.019, 0.188]).

This is a highly significant difference as determined by the chi-square test ( p = 0.004).

These findings indicated a highly significant association between the responses of participants related to knowledge of these four issues and AAS use ( χ 2 = 11.31, P = 0.004; χ 2 = 15.51, P = 0.001; χ 2 = 16.93, P = 0.001 and χ 2 = 17.08, P = 0.001).

After including village (Model 1a, Table 6 ), age group was borderline significant, and village was highly significant (p = 0.004).

Tb.N, a trabecular bone morphometry parameter with the highest value, was highly significant (OR = 19,062.087, 95% CI: 22.233–16,343,266.88, p = 0.004), indicating a detrimental micro-architectural shift attributable to significant trabecular thinning despite no significant change in BV/TV.

Notably, such differences remain highly significant ( p =0.004 for CK7 and p =0.009 for MUC5AC) when the analyses were restricted to jejunal-ileal tumours only (i.e. 50 CrD-SBCs vs 45 no-PID-SBCs).

Although the correlation between the maximum increases of CRP and IL-6 after LPS stimulation was highly significant (r = 0.81, p = 0.004), the correlation between the maximum increase in kynurenine/tryptophan and the maximum increase in IL-6 was not significant (r = 0.61, p = 0.06).

The prediected linear regression was highly significant (R 2 =0.345, r =0.59, P=0.004).

The backward stepwise multivariate logistic regression model was further performed to investigate the risk factors of treatment outcomes ( Table 3 ), and the results demonstrated that Staphylococcus aureus [Standard β value, 3.073; adjusted OR (aOR), 21.614; 95%CI, 2.829–165.144; p = .003) was a highly significant risk factor for treatment failure, followed by NLR (Standard β value, 0.319; aOR, 1.376; 95%CI, 1.105–1.713; p = .004), age (Standard β value, 0.042; aOR, 1.043; 95%CI, 1.007–1.079; p = .018), PD vintage (Standard β value, 0.021; aOR, 1.021; 95%CI, 1.003–1.040; p = .025) and PLR (Standard β value, 0.010; aOR, 1.010; 95%CI, 1.004–1.017; p = .002).

The difference in salivary sialic acid and fucose levels in all the study groups was highly significant ( P = 0.004) [ Table 1 ].

At the same time, we found a highly significant sex × area × species interaction (F 1,164 , P = 0.004), suggesting that sexual dimorphism depends on the island size, but with species-specific patterns.

Only two observers had very good Intraclass Correlation Coefficient (ICC) (0.757), which was highly significant ( P = 0.004).

Notably, after controlling for interaction between PDL1 and HLA-I in the model, HLA-I homozygosity emerged as having a highly significant association with OS (HR=3.70, 95% CI 1.53 to 8.95, p=0.004).

For treatment with statins alone (177 matched sets) and ACEIs/ARBs alone (90 matched sets), the adjusted ORs were 0.56 (95% CI 0.39–0.93, p = .024, SMD = 0.08) and 0.52 (95% CI 0.23–1.17, p = .11, SMD = 0.006), respectively ( Table 3 ). Using Gray’s test, the CIF, which accounted for the difference in mortality between the statins + ACEIs/ARBs vs no statins and no ACEIs/ARBs, was highly significant; p = .0040 ( Figure 2(c )).

Although the abundance of Clostridium was not significantly correlated with the TUDCA or NorDCA concentration ( R = −0.3141, P = 0.3734 and R = 0.3482, P = 0.3194, respectively), a highly significant negative correlation was found between the abundance of Clostridium and the primary bile acid CDCA ( R = −0.8398, P = 0.0040) (Fig. 4c ).

For D 3,2 , the linear ZnO term was highly significant (β 2 = −19.7 nm, p = 0.004), indicating progressively smaller droplets at higher ZnO levels, while the quadratic linseed oil term (β 11 = +15.3 nm, p = 0.012) revealed a curvature that penalised very high oil fractions.