Here, we found a highly significant negative correlation between absolute Fe(II) concentrations and disease status (ρ = −0.56, P = 0.004) ( Fig. 1B ), though a similar relationship was not found for Fe(III) (ρ = −0.28, P = 0.179) ( Fig. 1C ).
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Carrying out this method, but excluding the final BMI range for males gives a highly significant result ( p = 0.004).
However, the dose in PTV 3cm was found to be a highly significant DM predictor (HR > 1, p = 0.004) when analyzing only VMAT patients with small and spherical tumors (i.e., sphericity > 0.5).
The backward stepwise multivariate logistic regression model was further performed to investigate the risk factors of treatment outcomes ( Table 3 ), and the results demonstrated that Staphylococcus aureus [Standard β value, 3.073; adjusted OR (aOR), 21.614; 95%CI, 2.829–165.144; p = .003) was a highly significant risk factor for treatment failure, followed by NLR (Standard β value, 0.319; aOR, 1.376; 95%CI, 1.105–1.713; p = .004), age (Standard β value, 0.042; aOR, 1.043; 95%CI, 1.007–1.079; p = .018), PD vintage (Standard β value, 0.021; aOR, 1.021; 95%CI, 1.003–1.040; p = .025) and PLR (Standard β value, 0.010; aOR, 1.010; 95%CI, 1.004–1.017; p = .002).
Of more concern is the highly significant difference in the baseline value among the groups ( p = 0.004), which was not statistically accounted for.
This survival advantage remained highly significant in the 60-day landmark analysis ( p = 0.004).
As shown in Figure 3 , its relative levels were increased in all the test and reference groups two days after surgery, with the AAG dressing (175%) showing a highly significant difference ( P = 0.004) compared to the control group.
suzukii , however, there was a highly significant relationship (r 2 = 0.585, ANOVA p = 0.004) that was due in large part to the wasp species A. japonica (strain AjJap) and Ganaspis sp.1 (combined strains G1Fl and G1Haw).
Only two observers had very good Intraclass Correlation Coefficient (ICC) (0.757), which was highly significant ( P = 0.004).
Total Tube Length: Network length metrics demonstrated a highly significant suppression, dropping from an untreated baseline of 5.28 +/- 0.77 mm/HPF down to 1.83 +/- 0.26 mm/HPF in the treated environment ( p = 0.004).
The individuals living in Cochran and Bailey Counties had high likely to have cognitively impaired (AOR: 1.807, 95% CI: (0.749, 4.360), p = 0.188; AOR: 1.674, 95% CI: (0.267, 10.489), p = 0.582) though the adjusted odds ratios are not statistically significant, on the other hand Parmer County had the highest cognitively impaired individuals (AOR: 39.188, 95% CI: (3.123, 491.671) and this adjusted odds ratio is statistically highly significant ( p = 0.004).
To determine whether the accumulation of platinum was related to hydrophobicity, log P was correlated with platinum concentration- time products in neurological tissues, blood and plasma (Figure 3). Highly significant inverse correlations were found between log P and platinum concentration-time products in DRG (r2 = 0.99; P = 0.004), sural nerve (r2 = 0.85; P = 0.025), sciatic nerve (r2 = 0.98; P = 0.0012), brain (r2 = 0.98, P = 0.0011) and spinal cord (r2 = 0.97; P = 0.0018).
Although PrxII was only increased by 1.9-fold, this change was statistically highly significant p = 0.004, and PrxII can be mechanistically linked to inflammation, hemolysis, and endothelial damage.
Tyrosine phosphorylation density scans were obtained for six of the experiments and revealed that 1-min application of NGF to distal axons resulted in a 2.4-fold increase in trk phosphorylation density in the cell bodies/proximal axons, which was highly significant ( P < 0.004) (Fig. 6 ).
Of interest, pathway analysis based on both plasma metabolites and gene transcriptome demonstrated highly significant ( P < 0.004) differences of PPAR pathway between I − and I + T1D/ND participants.
Finally, in the comparison between Grades IV and I, the clinical pain component remained highly significant (OR = 9.000, 95% CI: 2.0399–39.704, p = 0.004), while the psychosocial component (OR = 3.962, 95% CI: 1.0753–14.601, p = 0.039) and pain modulation (OR = 0.265, 95% CI: 0.0736–0.955, p = 0.042) also showed significant relevance. 4.
Crucially, the association between rs2241766 and increased AMI risk remained highly significant after multivariate adjustment (OR = 1.87, 95% CI [1.23–2.84], p = 0.004), suggesting that this is a robust biological finding rather than a statistical artifact.
The p-value was found to be highly significant for [8-OHdG (p = 0.004) and isoprostranes (IsoP-2α) (p = 0.000)], respectively, and further both [8-OHdG = 21.26 ± 3.19 pg/ml and IsoP-2α = 102.25 ± 7.59] levels were recorded significantly higher in the colon cancer patients as compared to the healthy group.
The data exhibited a highly significant negative direct effect of the DT intervention on IC (β = −0.373, p = 0.004, 95% CI [−0.618, −0.119]), alongside a significant positive indirect effect via AC (β = 0.083, p = 0.048, 95% CI [0.019, 0.188]).
When comparing mean fluorescence intensities, a three-way ANOVA for repeated measures with cell type and cytokine as within-subjects factors and infection status as between-subjects factor revealed a highly significant three-way interaction of cell type, cytokine, and infection status ( F 1, 8 = 15.54, p = 0.004), reflecting an increased expression of IFN-γ in CD4 + lymphocytes (post hoc two-sample t test: t 4.3 = 2.31, p = 0.036, one-tailed), while no further significant differences were observed (all t < 0.916, all p > 0.197, one-tailed).
Distribution of verbal abuse with respect to age of HCWs is statistically highly significant (p value=0.004).
They are nevertheless highly significant (p = 0.004 in [PIN+] cells, one-tailed T-test), and we have modified the figure and text to clarify this.
The ANCOVA model for selection comparison between two morphs was also highly significant, explaining about 87.8% of total variation (F = 2.88, p = 0.004).
Compared with the MDRD-GFR and CMDRD-GFR, the NRI of the CKD-EPI-GFR was calculated at 0.10 and 0.09, and was highly significant ( P = 0.004 and P < 0.001).
The definite integral ±1 cm water from the median (DI ICP ) demonstrated a negative and highly significant correlation (-0.5213±0.17, p< 0.004) with the absolute difference between the measured and predicted median intracranial pressure (Diff ICPmd ).