Multivariate model for PEC was highly significant (R2=0.347; pmodel<0.001) with ENVM showing high strength of association (b=0.040; p=0.004).
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To determine whether the accumulation of platinum was related to hydrophobicity, log P was correlated with platinum concentration- time products in neurological tissues, blood and plasma (Figure 3). Highly significant inverse correlations were found between log P and platinum concentration-time products in DRG (r2 = 0.99; P = 0.004), sural nerve (r2 = 0.85; P = 0.025), sciatic nerve (r2 = 0.98; P = 0.0012), brain (r2 = 0.98, P = 0.0011) and spinal cord (r2 = 0.97; P = 0.0018).
2015 ), overexpression of the wild-type hDcr protein in NoDice/ΔPKR cells expressing the pCD-RLuc dsRNA insert did not induce repression of RLuc expression, when compared to the empty vector negative control, while a highly significant ( P = 0.004) level of inhibition of RLuc expression was detected in cells coexpressing the N1hDcr mutant, which shows a significantly enhanced ability to generate siRNAs from dsRNA substrates ( Kennedy et al. 2015 ).
A comparison of GABAergic cell number between young monkeys and aged animals classified on the basis of DR and DNMS task performance revealed a highly significant group effect in the full basal forebrain as well as for the rostral and caudal divisions (one-way ANOVA; DR task main group effects, BF: F (2,19) = 7.581, p = 0.004; rostral division: F (2,19) = 4.726, p = 0.022; caudal division: F (2,19) = 3.848, p = 0.040; DNMS task main group effects, BF: F (2,19) = 8.121, p = 0.003; rostral division: F (2,19) = 5.062, p = 0.017; caudal division: F (2,19) = 4.017, p = 0.035; Fig. 8 B , C ).
Correlation of TIM-3 mRNA expression with serum IgA was highly significant (r=0.425, P=0.004), but was weakly correlated with total serum protein (r s =0.283, P=0.049) and serum albumin (r s =0.297, P=0.047).
The association between NEE and StO2 remained highly significant ( p = 0.004).
This difference was large in magnitude and highly significant, t (6) = 4.56, p = .004, d = 1.72.
Finally, in the comparison between Grades IV and I, the clinical pain component remained highly significant (OR = 9.000, 95% CI: 2.0399–39.704, p = 0.004), while the psychosocial component (OR = 3.962, 95% CI: 1.0753–14.601, p = 0.039) and pain modulation (OR = 0.265, 95% CI: 0.0736–0.955, p = 0.042) also showed significant relevance. 4.
The individuals living in Cochran and Bailey Counties had high likely to have cognitively impaired (AOR: 1.807, 95% CI: (0.749, 4.360), p = 0.188; AOR: 1.674, 95% CI: (0.267, 10.489), p = 0.582) though the adjusted odds ratios are not statistically significant, on the other hand Parmer County had the highest cognitively impaired individuals (AOR: 39.188, 95% CI: (3.123, 491.671) and this adjusted odds ratio is statistically highly significant ( p = 0.004).
also found that there was a highly significant difference in olfactory loss in the RBD cohort who converted to PD (75%) compared to those who did not (48%, p < 0.004) (Fereshtehnejad et al., 2017 ).
Differences between the individual surface conditions were highly significant ( p = 0.004).
This analysis revealed even more pronounced clustering patterns based on different dietary groups, with highly significant differences (PERMANOVA: R 2 = 0.91343, p = 0.004) ( Figure 3 b).
On the other hand, a non-significant ( p =0.356) difference was found between moderate and mild autistic patients, and a highly significant ( p =0.004) decrease in oxytocin level was shown in severe autistic patients in comparison with moderate autistic patients.
These transformations were further justified, since there was an extremely highly significant difference found between the variances of these groups (F-test), i.e., that for first-year students was much greater than that for the final-year cohort ( p = 0.004).
Furthermore, a highly significant association ( p = 0.004) was found between individuals aged over 60 years and HL.
In Mossi ethnic group we noted that the CD3 + Panγδ + proportion remains stable through the season, whereas in Fulani ethnic group the proportion of these cells was double of that measured in Mossi ethnic group at the low transmission season and this difference was highly significant ( p = 0.004) (Figure 5 ) and remained significant during the high transmission season ( p = 0.04).
A highly significant relationship between the scores obtained by two methods was also observed ( P =0.004).
There was a highly significant association between HER2 positivity and increased VMP1 mRNA levels in all cohorts: in cohort 2 p = 0.004 ( S4 Table ), in TCGA p = 0.003 ( S5 Table ), and in METABRIC p < 2.2x10 -16 ( S6 Table ).
Sire breed had a highly significant influence on SCS (overall F-test p = 0.004).
Including sessile polychaetes, there was a highly significant difference in seagrass epifaunal communities between reference and aquaculture areas (PERMANOVA, F 1,24 = 4.23, p = 0.004) and also between regions (F 2,24 = 14.60, p < 0.001) with no interaction (F 2,24 = 1.68, p = 0.10; Fig 5A ).
MLT was highly significant in the KM, PKRM, and LKRM scenarios ( p ≤ 0.004), marginally significant in the IKRM scenario ( p = 0.049), and not-significant in the RM scenario ( p = 0.055).
High severity of dyspnea was also associated with worse outcome, HR 3.43 (1.28–9.20) P = 0.014 ( Table 4 ) but when the BRS and DSS were entered into the same model, the BRS remained highly significant (HR 1.94 per SD increment (1.24–3.02) P = 0.004) whereas DSS did not remain a significant independent determinant of the endpoint (NS).
For cells from naïve animals tested with E GABA = -35 mV, 4-AP increased the proportion exhibiting PAD-induced spiking but not significantly ( p = 0.079; Fisher’s exact test) whereas the 4-AP effect was highly significant for E GABA = -20 mV ( p = 0.004).
The value of each parameter was lower for atrial tissue than ventricular, and these differences were highly significant: p = 0.004 for ERP, p = 0.003 for CV and p < 0.001 for LAT.
of borderline significancep-value = 0.046
Presence of hyposalivation based on unstimulated salivary flow rate (IUS), although highly significant in the simple logistic regression model (OR: 2.02, 95% CI: 1.24–3.27, p-value = 0.004) was only of borderline significance when adjusted for confounders (OR: 1.68, 95% CI: 1.01–2.79, p-value = 0.046).