The proportion of cells displaying desmosomes after slug transfection was less than half that of control-transfected cells, and this difference was highly significant ( P < 0.004).
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Regression analyses indicated that for both dentate regions and for both behavioral measures there were highly significant correlations between system state (PCA1) and behavior ( Figure 3: Immobility in the FST – ventral: Spearman r = −0.63, p = 0.004***, dorsal: Spearman r = −0.63, p = 0.004***; Latency to eat in the NSF – ventral: Spearman r = −0.79, p<0.001***, dorsal: Spearman r = −0.81, p<0.001***).
All sensors showed highly significant differences ( p < 0.004).
Urine sodium of 130 mmol/L or greater was the most highly significant predictor of nonresponse to FR (OR 15.0; 95% CI, 2.4-95.8; P = .004) and while the closely-related Fürst ratio greater than 1 also predicted nonresponse, it performed less well (OR 2.7; 95% CI, 1.0-7.6; P = .05).
The difference in HAE between control subjects and MetSyn patients (not treated with statin) in the adjusted model was highly significant ( P = 0.004).
This is a highly significant difference as determined by the chi-square test ( p = 0.004).
Although the abundance of Clostridium was not significantly correlated with the TUDCA or NorDCA concentration ( R = −0.3141, P = 0.3734 and R = 0.3482, P = 0.3194, respectively), a highly significant negative correlation was found between the abundance of Clostridium and the primary bile acid CDCA ( R = −0.8398, P = 0.0040) (Fig. 4c ).
In Mossi ethnic group we noted that the CD3 + Panγδ + proportion remains stable through the season, whereas in Fulani ethnic group the proportion of these cells was double of that measured in Mossi ethnic group at the low transmission season and this difference was highly significant ( p = 0.004) (Figure 5 ) and remained significant during the high transmission season ( p = 0.04).
For comparison, only 10.3% of the VGLUT2 boutons that were in the vicinity of the cell showed eGFP and this difference is highly significant ( p = 0.004; Wilcoxon matched pairs).
Second, we compare the 65 genes closest to the published GWAS T2D loci with our 3,597 T2D-DMR genes, and find highly significant overlap of genes (Fisher’s test P =0.004).
For treatment with statins alone (177 matched sets) and ACEIs/ARBs alone (90 matched sets), the adjusted ORs were 0.56 (95% CI 0.39–0.93, p = .024, SMD = 0.08) and 0.52 (95% CI 0.23–1.17, p = .11, SMD = 0.006), respectively ( Table 3 ). Using Gray’s test, the CIF, which accounted for the difference in mortality between the statins + ACEIs/ARBs vs no statins and no ACEIs/ARBs, was highly significant; p = .0040 ( Figure 2(c )).
Serum Levels of sCD30 Renal transplant recipients showed relatively high levels of sCD30 which ranged from 2.252 U/mL to 97.144 U/mL, mean = 20.669 ± 18.713 U/mL, compared to that of controls which ranged from 0.291 U/mL to 18.242 U/mL, mean = 5.517 ± 5.304 U/mL, with highly significant difference ( t = 4.322, P = 0.004) ( Figure 2 ). 3.3.
This difference was highly significant ( P = 0.004).
An ANOVA on the combined data revealed a highly significant overall effect of early life intervention (F = 9.714, p = 0.004), but no overall sex effect (F = 0.034, p = 0.856).
The results revealed a highly significant main effect of relatedness, F (1, 29) = 9.50, MSE = 32, 294, p = 0.004, showing that response latencies were faster in the related condition than in the unrelated condition.
In addition, the children of the MIPAS-Family group reported highly significant reductions of the headache frequencies (Pre–Post 1: z = −2.841, p = .004; Pre–Post 2: z = −3.126, p = .002), whereas the children of the Biofeedback group only showed a significant improvement for the Pre–Post 1 comparison ( z = −2.333, p = .02).
In contrast, the ratio of SM resistant in non-Beijing genotype (32.4%) was higher than that of Beijing (27.9%), the difference of which was highly significant (χ 2 = 8.26, P = 0.004).
The effect of treatment on SOD activities was highly significant ( P = 0.004 ), and post-hoc analyses revealed that SOD levels in the GH group were statistically lower than those of in C and G.
While still low, the sensitivity for DR in Indigenous Australians (32%) was 3.5 times higher than for non-Indigenous Australians, and this difference was found to be highly significant in logistic regression (p = 0.004).
When this correlation was controlled for familiarity, it became highly significant ( N = 7, r = −0.951, P = 0.004).
The definite integral ±1 cm water from the median (DI ICP ) demonstrated a negative and highly significant correlation (-0.5213±0.17, p< 0.004) with the absolute difference between the measured and predicted median intracranial pressure (Diff ICPmd ).
The Antisocial facet predicted in the other direction with a more pleasant experience at trend level ( β = 0.24, SE = 0.13, p = 0.063 [90% CI = 0.03, 0.44]) and highly significant less excitement ( β = −0.44, SE = 0.15, p = 0.004 [90% CI = −0.69, −0.19]).
Correlation of TIM-3 mRNA expression with serum IgA was highly significant (r=0.425, P=0.004), but was weakly correlated with total serum protein (r s =0.283, P=0.049) and serum albumin (r s =0.297, P=0.047).
Of interest, pathway analysis based on both plasma metabolites and gene transcriptome demonstrated highly significant ( P < 0.004) differences of PPAR pathway between I − and I + T1D/ND participants.
This finding was highly significant for ADP response measured using platelet aggregometry (fentanyl 40.6% [ ± 19.2] vs. no-fentanyl 25.2% [ ± 10.8], p = 0.004).