“highly significant”

We found that recombination happened more often in the middle of core regions at a small but highly significant level (Kolmogorov-Smirnov test; p-value=8.8e-09).

The correlation between these phenotypes is numerically small ( r 2 = 0.03) but highly significant ( p = 8.89 × 10 − 9 ), likely due to the large sample size.

We again confirmed a highly significant association in an overall analysis stratified for the populations, with an odds ratio of 0.46, 95% CI 0.35–0.60, P = 8.94 × 10 −9 (Table 1 ).

Both skewness and CV successfully detected microtubule bundling during PPB formation, with the skewness and CV values for differences between the images with and without bundling being highly significant, but more so for CV (Mann–Whitney U-test, P = 8.947e−09 for skewness and P = 6.202e−14 for CV; Fig. 3 B, C, Supplemental Fig. 5 B).

CeaGO analysis reported "chemokine" as highly significant from a statistical perspective ( p -value = 9e-09 for cluster NO. 1, and 3.4e-06 for cluster NO. 2).

Both allelic and genotypic comparisons between Patna and Vaishali districts were highly significant (allelic χ 2 2 = 37.1, P = 9 x 10 −9 ; genotypic: χ 2 3 = 21.4, P = 9 x 10 −5 ).

Two microRNAs, miR-29a and miR-29c, were disclosed and further meta-analysis of the six mRNA expression datasets showed that these two microRNAs were highly significant based on the Fisher p-value combination (p = 9.14×10 −9 for miR-29a and p = 1.14×10 −6 for miR-29c).

The ANOVA of flaA -SVR groups from caecal isolates demonstrated a highly significant difference in the numbers of isolates between flaA -SVR groups ( P = 9.37 x 10 −9 ).

Among them, the MCV level was highly significant (nominal p = 9.8×10 −9 ) in association with the DYRK1A -SNP1 (c.2989 G<A), and explained 4.9% of the phenotypic variance.

5e ), and the difference in means was overall highly significant ( p = 9.95 * 10 −9 , two-sided t -test based on the data in Fig. 5d ).

SRI had highly significant negative linear (Pearson) correlations with standard deviations of sleep onset time (r = −0.66, p < 10 −8 ), wake time (r = −0.62, p < 10 −7 ), and mid-sleep time (r = −0.62, p < 10 −7 ).

All bleaching groups exhibited a highly significant and greater whitening difference compared to the control group (data not shown; p < 0.00000001, as determined by Dunnett's post hoc test).

Notably, the gene candidates THBS1 and IL18RAP exhibited highly significant upregulation (LogFC > 1.9, p < 10−8) in the independent GSE28750 cohort, confirming that our network-based prioritization captures clinically relevant expression changes.

This effect was highly significant (mixed-effects regression, N =43, P =10 −8 , Fig. 2c,d , Supplementary Table 2 , triple interaction between reward, transition type and colour deviation difference).

This difference is significant for six of the 12 genes ( p <0.05), and highly significant when all 12 genes are pooled ( p <10 −8 ; Table 3 ).

In this analysis, 263 p53 target genes were co-bound by JMJD3, which gives a highly significant overlap between JMJD3 and p53 target genes (p<10 −8 ).

Biological underpinning of the shared genetic components—translational evidence from mice For each of the Master PCs, the top-500 correlations across all records of the Amygdala Cohort Database, ranked by the Genetic Correlation (Spearman's rho), were strong (absolute value ranging from 0.7 to 0.9), and highly significant ( p < 10 −8 , Supplementary Tables 5, 6 ).

This test also shows that the difference between AI and human text is highly significant (− log 10 (p)≈8, p ≈ 3.69 × 10−9), and it is due to AI text often having less variety in its vocabulary.

These genes were chosen on the basis of showing highly significant self-linkage ( p < 10 −8 ) and at least a 1.2-fold difference in expression between segregants bearing the BY and RM alleles, such that no false positives and only one chance trans linkage due to a nearby gene were expected (see Materials and Methods ).

The results show also a highly significant p value for vessel diameter in the DCP in SWS patients compared to controls ( p = 0.00000001) ( Table 2 ).

Indeed, we found a highly significant association between high histone signals in FFPE-CUTAC samples and rapid patient recurrence ( p <10 −8 , Fig. 4B left, fig.

These genes were either associated with resistance to both lead and cadmium in both sexes or had highly significant ( P < 10 −8 ) effects in any one condition.

Statistical analysis of the asexual parasite prevalence by Chi-square test showed a highly significant reduction of the prevalence with increasing altitude ( χ 2 = 55.74, df =2, p =10 −8 ).

These measurements, distinguishing biopsy-positive from biopsy-negative men, were highly significant ( P < 10 −8 ; 100% sensitivity and 81.8% specificity).

This enrichment is highly significant, as only 5.5% of informative sites overlap a DSB hotspot (p < 10 −8 , calculated from 10 8 permutations; see ‘Materials and methods’—‘Inclusion criteria’).