The result is plotted in Figure 4 , illustrating the finding that HERVK PBA increases significantly with age (r = 0.357, P = 0.002) (It can be seen in Figure 4 that there is a high PBA value; if that is removed from the analysis, the positive association between and HERVK PBA remains strong and highly significant [r = 0.326, P = 0.005], attesting to the robustness of this effect). 3.4 HLA alleles in the very old and their association with virus PBA We then analyzed the PBAs of the 13 viruses in 11/13 VOA alleles (alleles C*02:02 and C*03:02 could not be modeled by the IEDB NetMHCpan affinity tool) using a repeated-measures analysis of variance (ANOVA), where virus PBAs were the dependent variables.
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Statistics were based on the p -value obtained by the significance test method, with p -value < 0.001 considered as a highly significant difference, 0.001 < p -value < 0.005 considered as a significant difference, and p -value > 0.005 considered as no significant difference.
However, the test for homogeneity of effect sizes was highly significant ( Q = 25.14, p = .005), which suggests that the variance among the included effect sizes was greater than expected by sampling error.
Regarding the results obtained with the PCR test in milk from lactating women and in blood from newborns from the four hospitals studied, a highly significant association ( p < 0.005) was observed between PCR positivity in milk and PCR positivity in newborns’ blood. 3.2.
The PPI-enhancing effects of 0.1875 mg pramipexole were highly significant in this subgroup ( F = 10.53, df 1,16, p = 0.005; d = 0.79; Fig. 3b ).
It was found that Rosaceae SEP1/2 -like genes had a highly significant ( p < 0.005) near twofold increase towards positive selection compared with non-Rosaceae orthologues (H1; Fig. 5a ).
A highly significant association between an increase in number of lesions in the brain and PFS was observed (HR1.13, 95% CI 1.06-1.21, adjusted P < 0.005).
Highly significant positive correlations between ASL-ATT and CTP-MTT were obtained by voxel-level-wise associations in the gray matter, white matter, and whole brain (all P < 0.005), and the average Pearson correlation coefficients were 0.787, 0.707, and 0.799, respectively.
Moreover, there was a highly significant (** P <0.005) increase in TAG levels ( Figure 5b ) on average by 176.4% in the LPL-OV line.
We identified 175 and 189 probe sets (genes) with highly significant strain differences (p<0.005, Benjamini-Hochberg multiple test correction) at 2 and 4 weeks, respectively.
There was a highly significant association between stage of USC and diagnosis of VTE ( p =0.005).
When compared to skin spacers, the proportion of shared spacers in saliva over time in each subject was highly significant (p < 0.005 in all subjects for SGII and SGI spacers) (Additional file 1 : Table S4).
( 1997 ), evaluating 29 patients for 180 days preceding the 1‐year post‐transplant exam, showed a highly significant inverse correlation ( p = 0.005 in univariate analysis) between CD4 + T cell counts and total infection score (i.e., frequency and severity) but not with CD8 + T cell numbers, B cell numbers, serum immunoglobulin levels, or delayed hypersensitivity responses.
Results A total of 118 gene transcripts surpassed the highly significant threshold ( P < 0.005, fold change > 1.2) in expression microarray analysis from triplicate cultures.
The analytical approach for this study was informed by our prior findings: although sex is traditionally included in REE PEs ( Appendix A ), our previous regression analysis on this cohort demonstrated that sex was not a statistically significant predictor of measured REE ( p = 0.06), whereas body weight and height remained highly significant ( p < 0.005) [ 10 ].
In Model 2, all the scores were negative and the multivariate test highly significant ( p = 0.005).
Data have been considered statistically significant with a p -value <0.05 (asterisk) and highly significant with p -value <0.005 (two asterisks) [ 28 ]. 4.8.
Whereas there was no statistically significant difference in disease scores between iNOS KO and wild-type mice that did not receive IL-12 ( P = 0.74), scores of IL-12–treated iNOS KO and IL-12–treated wild-type mice differed at the highly significant probability value of P < 0.005.
Supplementary Material The Supplementary Material for this article can be found online at: https://www.frontiersin.org/articles/10.3389/fphys.2019.00343/full#supplementary-material FIGURE S1 (A) Exemplary two-choice feeding assay using leaf disks of poplar (p) Populus nigra and willow (w) Salix viminalis indicates highly significant feeding preference of adult C. populi for poplar over willow ( ∗∗∗ P < 0.005; t -test); n = 5.
This supplementary analysis confirmed a highly significant community separation with remarkably robust explanatory power (Adonis: R 2 = 0.83, p = 0.005).
The highly significant correlation (p = 0.005) between the item “I may use the checklists and observation grids as reference in the future” and the item “I would like to participate in a similar clinical skill laboratory again” emphasizes how important instruments created by students are, how students considered them to be one of the results of the laboratory sessions, and how crucial they were in encouraging students to contemplate the possibility of participating again in similar activities.
A highly significant interaction with G2 gender ( p = 0.005) was observed.
Corresponding Mann-Whitney U tests were highly significant (all p < 0.005), and these associations withstood adjustment for multiple testing.
Consistent with the previous study (Chen et al , 2019a ), our analyses revealed a highly significant correlation ( r = 0.9739; P = 0.005) between the EC 50 values of five PARPi (thioparib, talazoparib, olaparib, rucaparib, and veliparib) in the DSB FA model and their average cytotoxic IC 50 values in 16 HR‐deficient cell lines (Fig 1D ; Appendix Table S2 ).
The difference between the groups was statistically highly significant (p = 0.005).