There was a highly significant time effect, group effect and interaction between time and group ( p < 10 –6 ).
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Differences between populations accounted for only 6.96% of the variance, but was highly significant ( P < 1.0 * 10 −6 ).
Global analyses identified a total of 2,053 sites with overlapping peaks, and statistical analyses showed that this overlap is highly significant ( Figure 2 B) (p < 10 −6 , calculated using a permutation test with 1.0 × 10 6 iterations).
ANOVA with the main factor Age-Group (adults, children) and repeated measures factor Velocity (3 conditions) revealed a highly significant effect of Velocity on gamma power (F (2,122) = 172.8, ε = 0.87, p < 1e −6 ; η 2 = 0.74), but no effect for the Age-Group or the Age-Group*Velocity interaction (p’s > 0.6).
The results are highly significant with p < 0.000001.
We concluded that our finding of 33 cases of positive selection on mitochondrial biogenesis genes is highly significant (simulated P < 10 −6 ) and not caused by an expression or sequencing bias.
Prior to statistical analysis, SNP data were filtered, using the BITE package 61 in R v4.0.5, according to the following criteria: (i) SNPs with call rates less than 95%, (ii) minor allele frequencies less than 5%, (iii) missing genotypes more than 5%, and iv) SNPs with highly significant deviation from the Hardy–Weinberg equilibrium ( P -value < 10 −6 ) 62 were eliminated.
The correlation coefficient (r = 0.44) was found to be highly significant (p<10 −6 ).
When assuming a random distribution of microRNAs, the presence of 105 microRNAs in LINE-free regions is highly significant using a binomial distribution (expected number of microRNAs = 62; p<10 −6 ).
Both values were highly significant when compared with the null hypothesis of no discriminative capacity (AUC = 0.5, p < 0.000001), indicating that the model performs markedly better than chance.
These complex conversions explain the highly significant deletion bias observed at the 9A/19A (RR = 0.00; P < 1 × 10 −6 ), favoring the transmission of the 9A over the 19A ( Table 1 ).
All results were highly significant with p < 0.000001.
A very highly significant increase of Ang‐2 concentration ( p < 0.000001) was observed in CSF of MA patient in comparison with CTRL subjects (Fig. 1A ).
This interpretation is further supported by the Pairwise Homoplasy Index (PHI) test implemented in SplitsTree, which returned a highly significant result ( P < 1e-6), suggesting that the observed pattern of site incompatibilities is unlikely to arise under a strictly clonal (non-recombining) model.
2 ), of which two, on chromosomes 3 and 5, are highly significant ( P < 10 −6 ).
To find 44 of 46 studies showing a positive risk ratio was very highly significant, P<0.000001.
Genes differentially expressed in association with upl3‐5 are linked to stress responses and metabolism To identify the biological processes that were most likely influenced by the mutation in AtUPL3 in association with infection by cyst nematodes, we focused on genes that showed highly significant differential expression between the upl3‐5 mutant and wild‐type Arabidopsis plants (−log 10 ( P ) > 6).
All 157 SNPs with highly significant associations ( P <1 × 10 −6 ) in this region, were in high linkage disequilibrium with rs188686860 and rs115635831 ( r 2 >0.90), and were located proximal (Hg19: 201,717,014-201,995,860) to the CASP8 gene ( Supplementary Table 15 ).
The inhibition of each infection by heparin was highly significant ( P < 10 −6 by χ 2 test, comparing infected and uninfected populations).
Furthermore, the comparison of the FMCA survival curves for TC and CRISPRa-RPA1 groups using the factorial ANOVA produced a highly significant difference ( p < 0.000001).
Separation among individual genomes into FREE and PATH distributions along the LDA axis was highly significant (p<10 –6 indicated by the gray box).
In contrast, highly significant differences were observed among the crop species (F 2,18 = 615.70, p < 0.000001; Table 1 ).
Results Meta-analysis of 9953 females combining discovery (N = 4658) and replication (N = 5295) stages detected four (rs11162584, rs6760543, rs828104, rs56137030), six (rs139702234, rs2341967, rs73059848, rs5020945, rs550532151, rs61971548), and two genetic variants (rs7722169, rs7206790) suggesting a highly significant association ( P < 1×10 −6 ) with BMI, WHR, and WC, respectively.
Among those metabolites, LysoPC (18:0/0:0), SM C24:0, PC O‐30:0, and dodecanoylcarnitine showed a highly significant increase ( p < 1 × 10 −6 ), while propenoylcarnitine showed a significant decrease ( p < 0.001) (Table S1 , Figure S3 ).
[ 7 the correlation between nodularity and infection is highly significant (p<0.000001).