“highly significant”

Three homogenous studies reporting procalcitonin documented a highly significant value ( p < 0.00001) with a I 2 value of 57% and odd ratio of 5.77 (95%CI: 3.35, 9.95) beyond the cut off value of 0.1 ng/mL [ Figure 6b ].[ 14 , 15 , 20 ] Investigation of heterogeneity Heterogeneity was found in all the comparisons with I 2 value ranging from 56% to 99% [ Table 3 ].

Mander’s overlap coefficient also showed a strong increase (>0.7), indicating that the majority of autofluorescent signal colocalized with mitochondrial structures under high-dose conditions. Statistical analysis on Pearson’s r coefficient using one-way ANOVA revealed highly significant group differences across all three conditions: AF-DAPI ( F (2,66) = 139.52, **** p < 0.00001), AF-MitoTracker ( F (2,68) = 28.68, **** p < 0.0001), and DAPI-MitoTracker ( F (2,66) = 36.53, **** p < 0.0001).

Male respondents reported always using rubber dam for posterior composites (39; 21%) more than the female respondents (13; 6%), which was highly significant (U = 14041.5, p <0.00001).

A total of 90 highly significant QTL (245 SNPs; p < 10 −5 ) were identified for salinity-related traits with the strongest associations detected for root Na + content followed by root Na + :K + ( Fig 2A and 2B , respectively).

There was a highly significant correlation between both dynamics rates (R = 0.769, p < 0.00001).

S3C ), there was a highly significant difference between all groups when clustered by degree of substrate consumption (Kruskal–Wallis p value <0.00001; Fig.

Future habitat suitability variation Pearson’s correlation coefficients between the habitat suitability maps generated for the different timeframes (2041-2060 and 2061-2080) and future climate scenarios were all higher than 0.999 for the ALP models and between 0.991 and 0.999 for APE; all the correlations were highly significant after Dutilleul's correction for spatial autocorrelation (p < 1×10 −5 ).

The differences were highly significant ( p < 0.00001) for both a 2 h treatment and an overnight treatment, suggesting that if we had used the earlier material in the second trial it could have proved more effective.

There was a highly significant correlation in the methylation status of the MGMT promoter region and MGMT protein expression ( p < 0.00001, Fisher exact test).

At a general hospital level, Hellgren et al., retrospectively analyzing data from 83 patients with RRMS, PPMS, and SPMS, reported a highly significant reduction of ARR induced by rituximab (500 or 1,000 mg every 6–12 months) from mean 0.38 ± 0.5 before treatment initiation to mean 0.05 ± 0.19 at follow-up (p<0.00001), with a global reduction by 87% ( 82 ).

In unadjusted models, all indices maintained highly significant associations ( P < 10 −5 ), indicating predictive capacity beyond shared variance.

4 A2 ) showed that the suppression is highly significant during the cue period (Z^ = −7.74, P < 0.00001).

In blood-based samples (4 studies), the pooled log odds was 0.99 (SE = 0.23), with no heterogeneity (I2 = 0%) and a highly significant overall effect (Z = 7.29, P < 0.00001).

Again, the difference is highly significant ( P -value < 0.00001).

They found a highly significant difference in mean %EWL of 17.98% (95%CI: 8.37-27.58, P < 0.00001) in the balloon group in comparison to the sham/life-style modification group.

Gender differences in normal individuals Figure 1 A shows that there are no significant differences in QRS-amplitude sum in the six limb-leads between males and females ( P = 0.78), but there are highly significant differences in QRS-amplitude sum from the six chest-leads, with values in females being lower ( P = 0.00001).

In the SA27063 × A17 F 2 population a highly significant quantitative trait locus (QTL, LOD = 7.37; P < 0.00001) named r esistance to the n ecrotroph P homa m edicaginis one ( rnpm1 ) genetically mapped to the top arm of linkage group 4 (LG4). rnpm1 explained 33.6% of the phenotypic variance in the population's response to infection depicted on a 1–5 scale and was tightly linked to marker AW256637 .

Overdose showed significant reductions from pre-operative to post-operative measurements, and the Nemo prognostic model was close to the final post-operative condition as reflected in the highly significant ANOVA (F = 13.66, p < 0.00001).

However, when considering the combination of adding CBCL+BPRS, this yielded a strong increase in prediction accuracy that was highly significant compared to considering only the SIPS (MSE of SIPS=0.74±0.62, MSE of SIPS+BPRS+CBCL=0.716±0.59, p<0.00001) or separately adding BPRS (p<0.00001), or CBCL (p<0.00001) (see Figure 3C ).

The difference between the MS and the control group regarding the frequency of a positive MRZ, MRZB or MRZBU reaction, as defined by a bi- or trispecific response, was highly significant ( p < 0.00001, Mann–Whitney U test, irrespective of whether the single steroid-treated control patient was included or not).

Preoperatively this range averaged 2.8 mmHg (SD 2.4, MAX 14, MIN 0) which was decreased to 1.8 mmHg (SD 1.7, MAX 10, MIN 0) at month 12, a difference that was highly significant (P<0.00001).

The combined effect SMD was 2.64 (95% CI: 2.38, 2.90), indicating a highly significant difference (P < 0.00001).

In a European patient cohort study of 110 candidate polymorphisms, Hhex SNP rs1111875, a major risk factor in T2D, was found to be a highly significant risk factor (p<0.00001) for AD, but only with the accompanying GSTM3 (rs7483) SNP ( 171 ).

The patient is assigned the high or low risk of relapse category if the score is ⩾2.41 or <2.41, respectively, with highly significant differences in RFS ( P <10 −5 ) and OS ( P <10 −5 ) between both groups.

Meanwhile, the triple interaction between OV, dwell-time advantage, and TMS condition remained highly significant ( β = –0.710, CI = [–1.019,–0.401], p = 10 –5 ).