“highly significant”

Ego-Dissolution Inventory (EDI) and Mystical Experience Questionnaire (MEQ) A paired comparison using the EDI revealed highly significant larger total scores for DMT compared to placebo ( T = 6.98, df = 12, p = 1.47e -5 , Cohen’s d = 2.67).

The association of rs3815087 remained highly significant even after correcting for multiple comparisons, both at allelic (FDR corrected p = 1.48 × 10 −5 ) and genotypic levels (FDR corrected p = 2.05 × 10 −5 ) while for other SNPs, this association was lost after multiple corrections.

Conversely, all individual variants identified in our analyses showed directionally consistent effects in a meta-analysis of two European-ancestry studies of extreme longevity, and a test of association of a polygenic risk score of the variants was highly significant in the longevity dataset (p < 1.5 × 10 −5 ).

Strong and extensive pairwise LD was observed among highly significant SNPs around AX-177640219 ( p -value = 0.000015) on chromosome Araip.B08 from the 12,629,161 to 13,029,161 bp region ( D’ > 0.80) in which D’ varied from 0.036 to 1 ( Figure 5 d and Supplementary Table S5 ).

Both CCL17 ( Figure 1A ) and CCL18 ( Figure 1B ) expression were highly significant when analyzed in rank order based on Ridley-Jopling classification (non-parametric trend test, P = 1.5×10 −5 and 3.0×10 −8 , respectively).

This hypergeometric analysis indicates that the 4.1 fold greater enrichment in the RAG/CsNp genes was highly significant (p = 0.000015) whereas there was no overall change in growth factor receptor genes (-1.1 fold, p = .42) and significantly fewer genes were found in the apoptosis gene group than expected by chance alone (-2.2 fold, p = .02).

Case-control genotyping and association tests in the entire GWAS discovery cohort (n = 44) showed highly significant association of the IAR phenotype with FKBP6 SNP g.11040315G>A ( P = 1.51E-05), and significant association with SNP g.11040379C>A (p.166H>N; P = 0.004) ( Table 3 ).

The two-way ANOVA revealed a highly significant interaction between genotype and condition ( p = 1.53 × 10 −5 ), indicating substantial variability in carbon assimilation responses among genotypes.

Analysis of nucleotides coding for these 24 OB domain residues identified one non-synonymous change in 6,498 control exomes 14 compared with three in 105 melanoma families, emphasizing a highly significant enrichment of variants in the melanoma cohort ( P = 1.54×10 −5 ) ( Online Methods , Supplementary Tables 6 - 7 ).

Among upregulated biological process, proteolysis is the highly significant ( P = 1.60E-05) biological process and it was observed that, 22 genes involved in proteolysis were upregulated in crossbred testis (Fig. 2 ), which includes serine proteases, chymotrypsin like elastases and matrix metallopeptidases.

The difference is best seen in energy of alpha frequencies in the right frontal and central region, which is highly significant ( P = 1.6 × 10 -5 , P = 2.6 × 10 -5 ).

Mature B cells were not only able to distinguish between these groups in the class switched category, but also in the non-class switched category where the difference between TB and OLD was highly significant ( p = 0.000016) and between TB and the healthy control group where p = 0.025939 (not shown)).

This observation is supported by strong statistical evidence, with highly significant differences among PLGA conditions (ANOVA p = 1.61 × 10− 5 ; Kruskal–Wallis p = 7.3 × 10− 4 ).

The differences were highly significant ( p = 1.65e−05), whereby diploids possess ~6% of duplicated gonial cells, while HHL and HLL triploids had none.

Shapiro-Wilk normality test had a non-significant value ( p -value 0.1024) for the transformed data, while, it was highly significant for the original data ( p -value = 1.688e − 05 ) indicating the non-normal distribution for the original common bunt scores.

There was also highly significant difference among the three different genotype groups in terms of total morphine self-administered (p = 1.7 × 10 -5 ) and weight-adjusted morphine (p = 6.6 × 10 -5 ) (Table 1 ).

Specifically, the pairwise comparisons of effect sizes across body sites revealed a moderate and highly significant correlation between saliva and plaque (Pearson r = 0.30, p = 1.7 × 10 −5 ; Spearman r = 0.28, p = 8.2 × 10 −5 ).

3.2.4 Cameroon For SNPs present in three or more mosquitoes, the most highly significant SNP was in the cytochrome P450 CYP304B1 on chromosome 2 ( p = 1.7 × 10 −5 ).

ANOVA analyses of the treated leaves demonstrated highly significant effects of both sesquiterpene ( P = 1.70e -5 ) and application method ( P = 6.31e -5 ) on blade area ( Figure 8b ).

This analysis showed significant effects of both Instrument ( p < 8.28 × 10-5 , F = 19.68) and ROI ( p < 2.42 × 10-2 , F = 5.53), as well as a significant Instrument x ROI interaction ( p < 1.03 × 10-6 , F = 34.47) driven by a highly significant difference between cello playing and singing in hand motor regions ( p < 1.71 × 10-5 , F = 33.6).

The fact that we have 11 genes using exon2 (falls outside the chart) is highly significant statistically (p = 1.718378e-05).

A case/control series in hepatitis C related disease demonstrated highly significant detection (p<1.72*10 −5 ) of patients at high risk of developing HCC.

R s , VWC, and T s were all higher in eCO 2 than in aCO 2 ( Figure 1 ) which resulted in a highly significant interaction effect of VWC and T s ( p = 1.73 × 10 –5 ) that explained 31% of the variability in observed R s ( Table 1 ).

When Triticeae was marked as the foreground branch, the likelihood ratio test (LRT) was highly significant (P = 0.000017894).

identified a highly significant association with a synonymous coding variant, rs7853758 (L461L) , in the SLC28A3 gene with anthracycline-induced cardiotoxicity in children (OR = 0.35; p = 1.8 × 10 −5 , single marker test).