“highly significant”

Results The SNP rs1635529 for COL2A1 on 12q13.11 showed highly significant over-transmission to affected individuals (p=0.00007).

Data 4 ), which represents a highly significant intersection ( p = 0.00007, hypergeometric test).

The expression difference between VIGS and control plants was highly significant in a two-tailed Student's t -test of 2 ΔCt values (VIGS 0.1 ± 0.05; Untreated 0.53 ± 0.01, p -value = 7 × 10 −5 , Figure 3Bb ).

This highly significant oxidation of the cytosol (p value = 7 × 10 -5 ) is dependent on NOX2 activity, but independent of the most effective thiol oxidant produced in neutrophils, MPO-derived HOCl.

The difference between the two groups was considered highly significant, as the sum of chi square values comparing the two groups was 19.07 and p = 0.00007.

Correlation between PD and PDR performance We found a highly significant, positive correlation (Spearman's rank correlation, r = 0.72, p = 0.00007) between the individual performances in the PD and PDR tasks, i.e. subjects that needed a high number of trials to reach the criterion in the visual discrimination task also needed a high number of trials to reach the criteri

Across all tumor types, there was a similar range of cell viability when comparing Collagenase I and Collagenase IV, with mean viabilities of 25.18 ± 6.23% and 66 ± 15.51%, respectively, demonstrating highly significant differences ( p = 0.00007; pairwise Wilcoxon rank-sum test).

The model demonstrated strong predictive performance (AIC = 679.94, concordance index = 0.84) with a highly significant global log-rank p-value (p = 7.07 × 10 -5 ).

First, we investigated the possible role of DRB1*03:01 in MS susceptibility and we observed a highly significant effect: OR = 1.52, 95% CI 1.23–1.88, p = 7.1*10 −5 .

However, we detected highly significant linkage disequilibrium for 3 nuclear locus-pairs across populations after a sequential Bonferroni correction for k tests ( k = 703, p < 7.1 × 10 -5 ): One_MHC2-190 ( I = 0.433) and One_MHC2-251 ( I = 0.465); One_Tf_ex10-7 ( I = 0.632) and One_Tf_ex3-18 ( I = 0.084); One_GPDH ( I = 0.668) and One_GPDH2 ( I = 0.082).

We observed a highly significant causal effect of MCP on AD [IVW (OR = 1.12, 95%CI = 1.06‐1.18, p = 7.14 x 10 ‐5 )].

5A , the triple combination of enalapril (3.0 mg/kg), furosemide (2.0 mg/kg) and amlodipine (1.0 mg/kg) could decrease the MBP by −18.34 mmHg ± 2.75 mmHg, which was highly significant in comparison to placebo effects ( p = 0.000073) but narrowly missed the therapeutic goal of −20.4 mmHg (averaged MBP increase induced by renal interventions, pre RW versus week 14–58).

The effect size ratio is highly significant (OR 1.60, 95% CI 1.27 to 2.02, p=7.36×10 −5 ).

The observed count is therefore highly significant ( p = 7.4 × 10−5).

The pooled difference between Sr6 positive and null plants at 18 °C was highly significant ( p = 0.000074), whereas no significant difference was observed at 25 °C ( p = 0.75) (Fig. 2B ).

Abundance estimates provided by RepeatMasker showed highly significant positive correlation with those yielded by RepeatExplorer in both the Southern (Spearman r s = 0.84, N = 15, P = 0.000074) and Northern (r s = 0.97, N = 17, P < 0.000001) lineages.

ANOVA analysis revealed a highly significant effect of temperature on the immobilized enzyme, with a large F-statistic [F(9,20) = 7.75] and a very low P-value (p = 7.48 × 10 −5 ) (Supplementary Table 3 a and 3 b).

6 G), obtained by stratifying lung cancer patients into low or high risk strata depended on four model gene expression, presented highly significant survival differences ( p = 7.5e-5).

The correlation between the NME close to the TSS and the gene expression variability was highly significant (Pearson correlation test, average correlation = 0.23, average 95% CI = [0.21, 0.25], average P = 7.6 × 10 −5 ).

For the H3K4me3 mark, the separation at the level of PC1 = 0 was highly significant (p = 7.6x10 -5 , Fig 2A ), but not at lower PCs (see PC1 to PC5 in S3 Fig ).

The probability of all eight of the low MOI lineages going extinct, but none of the others, was highly significant (one‐tailed Fisher's exact test, df = 1, P = 7.7 × 10 −5 ).

Single peak promoters in our filtered dataset of 4,481 promoters had highly significant (Fisher's exact test, Bonferroni-corrected p-value < 7.8E -5 ) enrichment for the TATA-box binding motif, a confirmation of previous findings [ 8 ].

As shown in Table 3 , the PT1 group revealed highly significant differences from baseline to 3 months for Shannon index ( adj. p = 0.000078), observed species ( adj. p = 0.000025), and phylogenetic diversity ( adj. p = 0.000001).

This difference between SNP types was highly significant (GLME with binomial family of error distribution, LRT against null model, p ‐value = 7.874699e−05).

We observed a highly significant overlap between the DE genes from the two studies, using either a rank-rank hypergeometric overlap test (p = 7.9 × 10 −5 ; Methods), or a standard hypergeometric overlap test for genes DE at p < 0.05 in both studies (p = 2.03 × 10 −25 ).