“highly significant”

These two antigen assays showed a highly significant correlation with a Pearson’s r of 0.96 ( p < 0.0001) ( Supplementary Figure S3 ).

Data analyzed revealed that there was a significant effect of the forward speeds (FS) (p < 0.05), a highly significant effect for elevator velocities (ES) (p < 0.0001), and a highly significant effect for cutting knives speeds “CKS” (p < 0.01) on the collecting efficiency.

P values were represented as asterisks; p values of <0.05 were considered statistically significant: 0.01–0.05, significant (*); 0.01–0.001, very significant (**); 0.001–0.0001, highly significant (***); p<0.0001, extremely significant (****).

When comparing “periphery” and “interior” patterns, the difference in radial distribution of DAO-5 was highly significant (Mann-Whitney test, p <0.0001).

Although risk group classification was highly significant on univariate analysis (p=0.0001; worsened outcome with increased risk group), this finding disappeared on multivariable analysis.

In addition, viral titration of the supernatants displayed a highly significant ( p < 0.0001) reduction of extracellular viral infectivity ( Figure 3 B–G).

Genotypic effects were highly significant in nearly all environments ( p < 0.0001); the sole exception was 23_WL, where IR was non-significant ( p = 0.0876) and both traits showed low heritability (IR: H 2 = 0.19, h 2 = 0.03; SV: H 2 = 0.27, h 2 = 0.05) (Table 1 ), consistent with uneven disease pressure.

Following a 24 h exposure period, both cell models showed a highly significant response to the compound ( p < 0.0001) at 2.0–5.0 μM, with non-significant responses at 1 μM.

One highly significant cluster with a relative risk (RR) of 4.7(p<0.0001) included 32 hamlets and 27 cases in 33,609 population.

Validity and reliability of the scales The exploratory factor analysis of the FCV-S19 scale in our sample showed a KMO measure of 0.846 indicating adequate sampling adequacy, a highly significant Bartlett’s test of sphericity (χ2 = 5231.023, df = 21, p-value <0.0001).

Standard mean difference (SMD) was highly significant ( p < 0.0001) for all comparisons (Stable_MCI versus MCI_AD: SMD [95%-CI] Aβ(1-42) = 1.19 [0.96,1.42]; T-tau = −1.03 [−1.24,−0.82]; P-tau = −1.03 [−1.47,−0.59]; HC versus MCI_AD: SMD Aβ(1-42) = 1.73 [1.39,2.07]; T-tau = −1.13 [−1.33,−0.93]; P-tau = −1.10 [−1.23,−0.96]).

The percentage reduction from baseline disability scores revealed substantially greater therapeutic efficacy in group B, with a mean reduction of 65.20% with a standard deviation of 14.67% compared to 46.26% with a standard deviation of 18.42% in group A, yielding highly significant differences (t = -4.187; p = 0.0001) and a large effect size (Cohen's d = 1.183).

As expected, dMMR was associated with a substantial and highly significant improvement in DFS in CRC (HR RE = 0.62; 95% CI = 0.55–0.70%; p < 1e‐04), with moderate heterogeneity across studies (I2 = 47%, τ2 = 0.015, p = 0.036) (Figure 1 ).

Pearson correlation analysis showed a highly significant correlation between Nat-LTP and Wt-LTP (R 2 = 0.9491, p < 0.0001, n = 27; Fig. 2 , large panel).

The results clearly demonstrate highly significant CD4 + and CD8 + T cell allogeneic immunization in partners practising unprotected homosexual (p<0.0001 and p = 0.001) or heterosexual (p = 0.001 and p<0.0001) intercourse, respectively.

Baseline CSF apoB levels showed highly significant associations with t‐tau and P‐tau ( R 2 = 0.23 and 0.28, both P < .0001, Figure 2 ).

Correlation of intermediate and extensive TILs groups -combined- also showed a highly significant positive correlation with survival (p < 0.0001).

When articles were normalized to ensure that each journal counted equally, differences for Altmetric scores and number of tweets were highly significant ( p < 0.0001, Table 3 ).

Two-way ANOVA analysis of the hemorrhage area for the FUS Intensity groups indicates a highly significant main effect of FUS intensity (p < 0.0001).

Overall, there was a highly significant difference in RR between the group of MB-stained patients and those without ( p < 0.0001), even if analyzed separately for treatments.

The effect of mCPP was highly significant ( F 2.24 =29.0, P = 0.0001), but there was no interaction of drug and genotype.

There was a highly significant difference in galectin-3 levels among cases and controls when classified into sub-groups based on their LVEF (p<0.0001).

At the 6-week assessment, arm 1 and arm 2 exhibited highly significant reductions in THI and TFI scores relative to their baseline scores (Fig. 3 ; P < 0.0001, paired two-tailed t-tests; adjusted significance level for multiple comparisons is 0.0025 described in Conlon et al. 21 ).

In particular, the variable methanol % exhibited a highly significant ( p < 0.0001) influence on TPC yield.

This revealed a highly significant difference in the frequency of the three genotypes between the dead and alive mosquitoes (chi-square = 28.8; p < 0.0001) ( Figure 5 ).