“highly significant”

The use of ventilators for non-survivors (29.5%) was almost twice that given for the survivors (15.2%), and ICU admission was more than twice for those who died (21.2%) compared to that for the survivors (8.4%), both with a highly significant p -value ( p < 0.0001).

Furthermore, the total score was a highly significant predictor of IIH with area under the ROC curve of AUC = 0.952 (95% confidence interval: 0.903–1.000, p < 0.0001).

As shown in Figure 5 , all of the tested EGCNPs concentrations showed highly significant inhibition of BSA glycation (**** p < 0.0001) when compared to the non-treated protein/glucose mixture.

The correlation of nest density with the urbanization gradient was highly significant (r = 0.700, p < 0.0001) ( Figure 2 ).

The overall F ST and Ф ST values both showed highly significant isolation among all populations ( F ST = 0.20, p < .0001; Ф ST = 0.74, p < .0001).

On the other hand, the correlation of the MCQ scores with those obtained in the VP exam was highly significant (r = 0.452, p < 0.0001).

Comparison of CD3 staining within the spinal cord parenchyma, but not the meninges, across treatment groups revealed highly significant differences between all treatment groups and vehicle-treated controls (Table 3 One-way ANOVA parenchyma: F = 10.56, p < 0.0001).

In both groups the most frequent alleles were Ala-14 and Ala-16 ( Supplementary Table 2 ), but the Ala-14/14 homozygous genotype was predominant in CH patients, either in absolute numbers and in percentages ( Supplementary Table 2 , Figure 3A ), with a highly significant X 2 test for trends (p<0.0001).

As shown in Additional file 1 : Figure S1, the correlation of eGDR calculated using this formula with glucose disposal rate (GDR) measured with euglycaemic-hyperinsulinemic clamp in 140 T2D patients was highly significant ( r = 0.624; p < 0.0001); moreover, it was higher than that of Homeostasis Model Assessment – Insulin resistance (HOMA-IR) in the 85 patients with calculable values ( r = 0.441; p < 0.0001) and similar to that reported in the validation study in T1D individuals [ 25 ].

In a sensitivity analysis excluding two studies that included patients with THPT [ 28 , 30 ], the pooled effect remained robust and highly significant (SMD = 1.68; 95% CI: 1.53 to 1.84; p < 0.0001), with negligible heterogeneity ( I 2 ≈ 0%).

As displayed by Figure 3 A, neurons from both P149 lines and P34 2 show as compared to CTLRs neurons a visible reduction of nuclear area, quantified by scoring 50 neurons per sample, as highly significant ( p value < 0.0001) ( Figure 3 C).

However, multiple regression analysis indicated that the quadratic terms (X 1 2 , X 2 2 and X 3 2 ) were highly significant ( p < 0.0001) for the extraction of TPC and is revealed in Table 3 , as for the antioxidant activity.

The model was highly significant (R2 = 0.62, p < 0.0001) and genotype ( p < 0.05), step frequency ( p < 0.0001) and hematocrit ( p < 0.05) were independent predictors of the 6-MWT distance.

Subsequently, by ELISA assays, we found a highly significant correlation between TRACP5b and IL-8 ( p < 0.0001) and a lack of correlation with IL-6 ( Figure 7A ).

A highly significant association was found between histopathology and CBNAAT (p<0.0001) in the endometrial tissue of infertile patients.

The ANOVA results ( Table 1 ) suggest that the model was highly significant with a high F value (F model = 62.16) and a very low probability p -value ( p < 0.0001) [ 21 ].

Because the surgery-by-histology interaction term was highly significant ( p < 0.0001), we conducted Kaplan-Meier and log rank analyses comparing survival curves between treatments separately within histologies.

The ANOVA indicated a highly significant G × Y interaction [ p < 0.0001, F (66.45) = 1.112 for Fe] and [ p < 0.0001, F (62.43) = 1.112 for Zn].

At 38 days, when the first animal required euthanasia because of tumor size, tumors were 1,764 ± 1,526 mm 3 in the CA9 group and 126 ± 130 mm 3 in the control group ( Figure 5B ); differences in tumor growth were highly significant ( P <0.0001, twoway repeated measure analysis of variance with the Geisser-Greenhouse correction).

The analysis of the two-sample t -test has revealed significant deviations in run length, velocity, and off rate at higher and lower pH levels relative to the neutral pH of 6.9, with a highly significant probability ( p < 0.0001).

We then confirmed the intergroup similarity by the highly significant correlations for the normal and LPMC/F3 groups (within: R S = 0.87, n = 27, P < 0.0001; between: R S = 0.75, n = 64, P < 0.0001) ( Fig. 5 C ), as well as for the normal and extra groups (within: R S = 0.76, P < 0.0001; between: R S = 0.66, P < 0.0001) ( Fig. 5 D ).

The pair group comparisons of day 7 v/s day 15, day 45, and 6 months showed a highly significant difference of 0.64, 1.48, and 1.80, respectively, and P value = 0.0001.

We found a moderate but highly significant negative correlation between high SMAD1 expression and KEGG Apoptosis pathway inhibition across the ~ 1000 CCLE cell lines ( R = -0.1486, p < 0.0001) (Fig.

4 In 30 of 34 reviewed studies, persistent microscopic inadequate (R1) or macroscopic inadequate (R2) surgical margins were highly significant for LR compared with negative margins ( p = 0.0001), depicting the relevance of margin status on the outcome of BCT.

The ANOVA revealed highly significant results (F 2,127 = 16.54; p < 0.0001) with significant ( p < 0.05) reduction for both diazepam and FG7142 in comparison with saline, as revealed by Newman–Keuls post-hoc test for multiple comparisons.