“highly significant”

The linear model without the random effect between indentation modulus and the degree of mineralization is highly significant and the modulus increases with higher degree of mineralization (Fig. 8 A , linear model p < .0001).

For a-wave amplitude, a two-way repeated-measures ANOVA with treatment and intensity as factors found that both were highly significant ( p < 0.0001 for both), and Bonferroni post hoc tests indicated significant pairwise differences in the three highest intensities tested (−1 to 1 log cd s/m 2 ).

The number of SWATH windows was the most critical parameter with a highly significant (p < 0.0001) impact on the number of proteins quantified.

A highly significant treatment effect ( p = 0.0001) was obtained exclusively for LT, indicating that the mean response profile between the two groups differed only in the second year of repeated measurements ( Table 4 ).

By contrast, the discovery cohort had a median of four (p10-p90: 1-6) and five (p10-p90: 2-9) mutations at the first and second samplings, respectively, representing a highly significant increase in the number of mutations during disease progression ( P <0.0001).

Meta-analyses Random-effects meta-analysis of trials of adding SGAs versus placebo to antidepressants yielded highly significant superiority of SGAs overall (OR = 1.59 [CI: 1.44–1.75]; z = 9.16, p < 0.0001; Figure 1(a) ).

Looking at the association between BCR reactivity of DLBCL cells and the presence of hypophosphorylated Ars2 isoform overall, considering data from both cell lines and cases with cryospecimenderived recombinant Fab, the association was statistically highly significant (Fisher exact t -test: two-tailed P <0.0001).

Pooled analysis of all trials found a highly significant reduction in recurrence (RR 0·66, 95% CI 0·62 to 0·71; p<0·0001; figure 1 ) and breast cancer mortality (0·67, 0·61 to 0·73; p<0·0001; appendix p 7 ) with chemotherapy plus trastuzumab compared with chemotherapy alone.

Unlike other developed models, the highly significant HHV model ( P < 0.0001) for the solvolysis process only contained the independent terms.

Marbling Score and REA The mean marbling score evaluated in both laboratories for the striploins of different experimental groups showed greater values for the CAB striploins than for the CTNA counterpart ( Table 1 ), with highly significant differences ( p < 0.0001).

A weak but highly significant correlation (r=0.34, p=0.0001) was observed between the percentage of just-passing candidates correctly answering a part 2 question and ChatGPT’s probability of answering it correctly.

In both instances, the PHASE x TREATMENT interaction was highly significant (p < 0.0001), indicating that ghost crabs responded strongly to the addition of carrion ( Figure 2 , Table 2) .

Then, a two-way ANOVA factorial analysis revealed that the clinical state of the patients’ plasmas tested (“steady state” versus “acute phase”) had a highly significant effect ( p < 0001) on PS-exposure quantification.

Obtaining a tumor-free surgical margin decreases the incidence of a local recurrence (LR) of the primary tumor.[ 18 ] There are various risk factors associated with a positive margin, among them are: The extent of excision, age, large tumor size, multifocality, lobular histological type, and the number of positive lymph nodes.[ 19 ] In 30 of 34 reviewed studies, persistent microscopic inadequate (R1) or macroscopic inadequate (R2) surgical margins were highly significant for LR compared to the negative margin (p = 0.0001).[ 20 ] Microscopic disease resulting from a positive margin is more problematic because theoretically, cancer in the relatively hypoxic environment of the lumpectomy scar bed will be resistant to radiation therapy.[ 21 ] Furthermore, the inability to achieve negative margins may be a marker of an excessive tumor burden in the treated breast.

Results Quantity of DNA The test of the extraction protocols indicated that in the case of Qiagen Kit, on average, 8.15 ng (SE = 0.39, i.e., 815 ng/g of mandible) of DNA was obtained per sample, whereas the Promega protocol provided on average 19.20 ng (SE = 0.455, i.e., 1,920 ng/g of mandible) of DNA, and the difference was highly significant ( t test, t = 18.35, df = 17.65, p < 0.0001; Table 1 ).

On the other hand, podocyte damage groups (MCD, FSGS, MGN and amyloidosis) showed a statistically highly significant upregulation of podocyte CD73 ( p < 0.0001); the significant increase was consistent also when comparing single entities with negative controls ( p at least < 0.001).

, 2019 ), the correlation between hangover frequency and severity was highly significant ( r = 0.710, P < 0.0001), suggesting reverse tolerance.

During the baseline, ETD was already lower in Brasília Teimosa (emmean 9.16 ETD, 95% CI 8.03–10.28) than in Pina (12.2 ETD, 95% CI 10.8–13.7), with a highly significant difference (GLMM, estimate = −0.29, SE = 0.015, P < 0.0001).

Type III fixed effects test showed a highly significant (p<0.0001) effect of DxGP on RIN values but no significant effect were observed for G, D and GP on the trait.

Highly significant intraobserver agreement was observed between the measurements of the two 6 MWT trials (ICC = 0.92, 95% CI = 0.85–0.97; p < 0.0001).

Degrees of significance were assessed by three different rating values: * p 0.05 (significant), ** p 0.01 (highly significant), *** p 0.001 (extremely significant), and **** p ≤ 0.0001 (extremely significant) or non-significant ( p 0.05). 5.

A highly significant correlation between the expression of miR-125b and CRP/IgE levels (r = 0.86/r = 0.68; p < 0.0001) in asthma patients indicates the usefulness of this molecular marker for asthma diagnosis.

Overall, these highly significant (p < 0.0001) associations between epithelial and stromal marker proteins KRT19, CDH1, VCAN, and FAP with LMD-enriched tumor epithelium and stroma, respectively, were observed using the proteomic data from the additional 9 HGSOC cases assessed ( Figure 3 B).

ANOVA results ( Table 2 ) showed the model was highly significant ( P < 0.0001) with a non-significant lack of fit ( P = 0.742 > 0.05).

At 3dpi, two doses of VBI-2902a resulted in highly significant (p = 0001) viral load median reductions ( Fig. 8 a) of 4,45 Log10 (IQR 4,95–4,33)in the cranial lobe and 5,17 Log10 (IQR 5,69–4,39) in the caudal lobe relative to non-immunized animals.