“highly significant”

This underscores the protective role of Prxs, since it suggests that the ability of transferring Prx2 to the erythrocyte cell membrane and of releasing Prx5 in the plasma goes in hand with a milder ASD phenotype. Plasma Prx5 levels are suggestive of ASD Since the difference in Prx5 plasma levels between ASD and TD subjects was highly significant (p < 0.0001 by Mann–Whitney test), we calculated the Receiver Operating Characteristic (ROC) curve.

The significant effect of irrigation on stem length was observed only at later growth stages, with significance emerging at 3 MAT ( p<0.01 ) and becoming highly significant at 4 MAT (p<0.0001) .

In the analysis of variation among the frequencies in each ear alone, we noticed that it was highly significant (p<0.0001-t Student test) in all the frequencies for both the right and the left ears.

In particular, a highly significant ORR was seen in patients who developed skin disorders ( P = 0.0001), vitiligo ( P = 0.0004) and thyroid dysfunctions ( P = 0.0127) ( Supplementary Table S4 ).

The ANOVA table revealed that the F -statistics ( F = 381.22) was very large and the corresponding P value was highly significant ( P = 0.0001) or lower than the alpha value (0.05).

Differences between the two groups were highly significant (p<0.0001; unpaired T-test with Welch's correction), reflecting the recent and remote diversification histories of acute and chronic sequences, respectively.

Differences between vaccinated groups and non-vaccinated animals were highly significant ( p ≤ 0.0001).

The effects of inoculation on the percentage of root colonized by AM fungi depended on soil type as shown by a highly significant ‘soil type’ x ‘AM fungi inoculation’ interaction ( F 1, 12 = 34.39, P < 0.0001, Table 2 ).

The inclusion of modules A, P, M, and N in the VCogM model had a highly significant impact on the model's Top‐1 Accuracy ( p ‐value < 0.0001), while module U also had a significant impact on the VCogM model's performance ( p ‐value < 0.01).

The top five of these clusters with a highly significant enrichment ( p < 0.0001) in the obtained CB2 interactome ( Table 4 ) represent the ER (cluster 1), membrane (cluster 2), oxidoreductase (cluster 3), ER stress and cell redox homeostasis (cluster 4), and lipid metabolism (cluster 5).

The difference between the ability of the ZIKV-RT-PCR-positive and flavivirus groups (median ODr of 2.2 and 1.1, respectively) or ZIK-IgM-positive and flavivirus groups (median ODr of 3.6 and 1.1, respectively) to recognize ZEDIII was highly significant (Mean rank diff. = 103.3, p < 0.0001, Mean rank diff. = 123.2, p < 0.0001, respectively), whereas there was no statistical difference between the flavivirus and negative sera (median ODr of 1.1 and 1.2; respectively, Mean rank diff. = -13.75, p > 0.9999) or the ZIKV-RT-PCR-positive and ZIKV-IgM-positive sera (median ODr of 2.2 [1.7; 4.0] and 3.6 [2.0; 8.5]; respectively, Mean rank diff. = -19.82, p > 0.9999).

A paired t-test again showed this difference to be highly significant (p < 0.0001).

The difference at follow up was highly significant ( p < 0.0001) (Additional file 5 ).

After adjustment for the residual confounders, TAVI as compared with conservative management was associated with highly significant risk reduction for all-cause death and HF hospitalization (HR 0.46, 95%CI, 0.32–0.69, P = 0.0001, and HR 0.25, 95%CI 0.16–0.40, P<0.0001) ( Table 2 ).

Analysis of fitted curves shows that this change in dose response is highly significant (EC50 wild-type 2.06 μWcm 2 ; Efemp1 R345W 0.016 μWcm 2 ; F -test P < 0.0001, F = 50.94).

Geographical distribution of folate-mediated one-carbon metabolism pathway alleles and genotypes showing continental variation and intra-population differences in Mexican Mestizos In contrast to the additional four out of the eight variants analyzed, MTRR A66G, MTHFR C677T, A1298AC and MTHFD1 G1958A showed a gradient in the frequency between MEX groups and highly significant differences between AMI and EUR groups ( P values <10 −4 ).

Similarly, the mean number of days spent in hospital per patient per year was reduced from 9.8 to 1.3, which was highly significant ( t =5.678, d.f.=122, P <0.0001).

The number of eggs in the cluster had a highly significant positive effect on water percentage ( F 1,16 = 31.43, p < 0.0001).

This reduction was highly significant (P<0.0001) suggesting that Cbl is required for SLAP mediated receptor ubiquitination ( Fig. 6B ).

There was a highly significant difference in body mass index (BMI) between CRC patients and controls ( P < 0.0001).

Fluctuating asymmetry The signed FA variance estimation was highly significant relative to measurement error in both tarsus length ( χ 2 = 789.7, d.f. = 1, p < 0.0001) and rectrix mass ( χ 2 = 449.1, d.f. = 1, p < 0.0001) (electronic supplementary material, table S2).

The overall correlation coefficient observed between C6 and C6 Plus was highly significant ( P < 0.0001; r = 0.992; 95% confidence interval [CI]: 0.982–0.997).

Results Our data showed strong, highly significant correlation between arterial and peripheral venous lactate levels (r = 0.880, P < 0.0001), between arterial and central venous blood lactate (r = 0.898, P < 0.0001) and between central and peripheral venous blood lactate (r = 0.941, P < 0.0001).

We conducted a sphere formation assay on agarose-coated plates, which minimized cell adherence to the surface, and observed a highly significant increase ( p < 0.0001) in the number of spheres formed in the groups; BDFO and BNFO, respectively, as compared to the control group, BNFN whereas FDBO and FNBO cells did not show any considerable change (Fig. 4 a, b ).

The model-based estimate of the difference between the two in case of TRI was 57.5 s, and in CER was 144.2 s which is a highly significant improvement in both cases ( P < 0.0001).