“highly significant”

Correlations were also highly significant (p=0.0001) for NFF among different trails, with the coefficients ranging from 0.36 to 0.46.

While both 24 h and 1+23 treatment paradigms resulted in substantial loss of hair cells, there was nevertheless a large and highly significant difference between these treatments (Tukey's multiple comparison, p < 0.0001).

Although the interaction was not significant, post hoc simple effect analyses confirmed that the aforementioned trend was highly significant in prefrontal cells (simple effect of cycle, F 3, 2244 = 11.3, P < 10 −4 ), with inferior parietal cells showing a similar but more moderate trend ( F 3, 2244 = 3.32, P = 0.02).

While the 100 nM dose had no effect on the longevity of the N2 wild-type strain, worms treated with either 1 μM or 10 μM EAPB02303 displayed a highly significant lifespan extension compared to the control and vehicle DMSO groups ( p -value < 0.0001) ( Figure 1 A, Table 1 ).

This difference in T1b prevalence between the UL and no-UL groups was highly significant (χ2 = 57.6, p < 0.0001).

Eosinophil count reduction was higher in group B (96.1%) as compared with group C (85.4%) and group A (66.3%), with highly significant ( P = 0.0001) differences.

On both primary outcome days (Day 4 and Day 7), these rate differences were highly significant ( p < 0.0001), indicating clinically meaningful effects.

The log rank test analysis indicated that the difference between the survival curves is highly significant ( p < 0.0001).

The difference in percentage of biotype A observed with QD fluorescence in the anterior foregut or cibarium in these two treatments was highly significant ( P < 0.0001; Fisher’s exact test).

The results of the pairwise t-tests for TomatoRipen-MMT and the best baseline (two-stream CNN) indicated a highly significant improvement (t = 6.18, p < 0.0001) with very large effect size (d = 2.14).

Differences comparing MT/MT with WT/WT and WT/WT with Het are highly significant ( p < 0.0001).

All correlations remained highly significant ( P <0.0001) after controlling for ethnicity, socioeconomic status, birth weight, placental weight, gestational age at delivery, parity, tobacco smoking status (0, 1–10 or >11 cigarettes smoked per day), labor onset, labor induction, labor duration, oxytocin administration, tocolytic administration, antenatal steroid administration, APH, PTB, and PROM in multiple regression analysis.

A two-way ANOVA [Pre-post (pre/post, within-subject factor) × Music-type (no-music/high-tempo/low-tempo, between-subject factor)] applied to the SSRT in sham condition showed that the main effect of Music-type was not significant however, the main effect of Pre-post was highly significant (F(1,70) = 17.57; p = 0.0001) (Partial Eta Squared = 0.20).

The difference between the chromatic contrast sensitivity measured during fixation and saccades was highly significant (Mann-Whitney z = 7.96, p < 0.0001).

The difference in the ratio MUM/NSB/NBA between C x C (1.97/1.01/11.89) compared to C x NC (0.34/1.43/14.44) is highly significant ( P < .0001, Chi-Square).

benign or normal groups were highly significant ( p < 0.0001).

Similarly, the mean number of days spent in hospital per patient per year was reduced from 9.8 to 1.3, which was highly significant ( t =5.678, d.f.=122, P <0.0001).

The repeated measures analysis of feather brightness resulted in a final model that included highly significant effects of exposure time ( F 1,590.44 =26.09, P <0.0001) and pigment identity ( F 1,514.84 =4.06, P =0.044).

Highly significant differences were found among the treatments (χ 2 = 154.0; d.f. = 3; p < 0.0001).

In the GAM analysis simultaneously including GH and PE cases ( Figure 3C ), the smooth term of gestational week interacting with maternal log(UA) was highly significant (edf = 5.51, χ2 = 662.3, p < 0.0001).

The response surface quadratic model was highly significant ( p < 0.0001), and the lake of fit (lake of fit = 0.0710 > 0.05) was not significant.

The corresponding gait discriminant score displayed a highly significant ( P < 0.0001) differentiation between the mdx mice and WT controls and a significant shift toward WT in the SC and IV M23D treatment groups compared to the scrambled control group ( P < 0.05), indicating an M23D treatment effect on overall motor performance ( Fig. 7B ).

Likewise, there was a highly significant (p<0.0001) reduction in the total number of PCNA foci over the 16-hour timeframe with the average median number of foci only 2351 in HU cells compared to 6125 in controls (Supplementary Figure S4C ).

71 Analysis of the HPS also assessed simvastatin efficacy in subjects with and without diabetes and showed an effect consistent with the full cohort; 72 that is, simvastatin produced highly significant reductions (22%; P < 0.0001) in the first event rate for major coronary events, strokes, and revascularizations in subjects with type 2 diabetes.

A similarly designed study using everolimus (initiated at 4.5 months post-transplant) in 300 patients also showed a highly significant increase in eGFR at 1 year after transplant (eGFR 71.8 versus 61.9 ml/min/1.73m 2 , P <0.0001) [ 13 ].