“highly significant”

Among the outliers detected by coalescent simulations assuming a neutral island model, five were highly significant ( P <0.0001; Table 3 ).

We found highly significant positive correlations ( r > 0.91, p < 0.0001, n = 324) between the fragment intensities of all samples and only very minor and non-significant deviations from a slope of one, with Δsl ranging from 0.008 (NADW/EMW) to up to 0.243 (Lake/AABW) (Fig. 2 ).

While this scenario biased towards larger effects shows a highly significant modulation by the ‘best call’ (p < 0.0001, Figure 3—figure supplement 2B ), there appears to be no overwhelming population of trill-/complex-/flat-preferring neurons.

Even though average pre- and post-test scores were highly variable among schools (p<0.001, ANOVA) the pre- to post-change within each individual school was highly significant (p<0.0001, paired t test).

Bartlett’s test was highly significant (p<0.0001), further indicating that the sample was adequate for factor analysis.

In a Kruskall-Wallis analysis of the normalized frequencies of the Foa races 4 and 2 hetero- and homo-CATs, there were highly significant differences ( P < 0.0001) between the strains; the non-parametric Steel-Dwass multiple comparison test found highly significant differences ( P < 0.0001) between all pairs, i.e., there were highly significantly fewer (apparently non-existent) hetero-CATs than either homo-CATs, and there were highly significantly more homo-CATs of Foa race 2 than homo-CATs of Foa race 4.

For the PMHS, the KMO amounted to 0.955 and Bartlett’s Test of Sphericity was highly significant ( p < 0.0001).

The difference in the number and distribution of lesions in rAAV2/2[MAX]smCBA-Eylea and PBS control groups was highly significant ( p < 0.0001, Chi Square test), strongly indicating that rAAV-mediated over-expression of an anti-VEGF agent is able to prevent disease pathology in AMD (Fig. 5H ).

Although these increases were highly significant (ANOVA: F 25,429 = 1434, p < 0.0001; F 13,95 = 13.64, p < 0.0001), they were really small (see Supporting Information Tables S4 and S5 ) in units of percent (females vs. males) both in WT and KO animals. 3.3.

Between Groups I and III and Groups I and IV, there was a statistically highly significant difference ( P = 0.0001).

Although we could not directly compare the miRNA quantification provided by a probe hybridization-based technology (Agilent microRNA microarray) and a digital PCR technology, we analyzed the correlation in microRNA quantification between these two approaches, after data normalization, and observed a highly significant correlation of the data ( p < 0.0001, Spearman r > 0.7) for all the tested cancer types.

The losses at HD grades 2 to 4 for rostral putamen were substantial (>80%), and the difference between control and HD grades 2 to 4 was highly significant ( P < 0.0001).

Comparative evaluation was done between Group I and Group II, Group I and control group, and Group II and control group, all showed highly significant difference ( P < 0.0001) [Tables 1 – 3 ].

There are also highly significant associations with measures of nuclear grade including nuclear membrane irregularity, ( p < 0.0001), nuclear size ( p < 0.0001) and nucleolar size ( p < 0.0001) (Fig. 5d ) and with high-risk histological patterns of disease (Fig. 5e ).

Correlation of depression as per BDI with Self-esteem (RSES) and body image disturbances (BICI) A highly significant negative correlation of depression with self-esteem ( r = -0.678, P < 0.0001) and a highly significant positive correlation ( r = 0.6395, P < 0.0001) with body image disturbances was seen in our sample of CD [ Table 5 ].

The difference between the sta-1(RNAi) and akir-1(RNAi) animals is highly significant (p<0.0001; one-sided log rank test).

Two-way ANOVA revealed a highly significant effect of the genotype and the distance from the soma on the number of intersections ( p < 0.0001, F (1,4023) = 37.46 and p < 0.0001, F (26,4023) = 163.7, respectively), as well as a highly significant interaction between those two factors ( p < 0.0001, F (26,4023) = 2.488).

In terms of BFP, normal-weight individuals exhibited the lowest value (21.2 ± 4.7%), which increased steadily in overweight participants (26.5 ± 6.9%) and peaked in the obese group (33.4 ± 6.1%), with highly significant group differences (p < 0.0001).

Both LPO substrates mediated A/California/04/2009 viral inactivation beyond detection limit of the assay in the cell-free system which was highly significant (p<0.0001, for each substrate) ( Fig 3A ).

The results of the ANOVA test on vasculitis parameters were highly significant ( p < 0.0001, refers to Supplementary Table S1 ).

Summed fluorescence values relative to BF long-latency activity ( Figure 2 c) indicated a highly significant difference across the four groups, illustrating a strong reduction of neuronal assembly magnitude with maturation (F (3,120) = 9.613, p < 0.0001, one-way ANOVA).

All other comparisons between treatments across species are highly significant ( t 72 > 5.492, p < 0.0001).

The results obtained by both techniques were coincident and the correlation between microarray data and those measured by RT-qPCR were highly significant (Pearson’s r = 0.69, P < 0.0001) in spite of the high difference in sensitivity and accuracy between these experimental procedures. 3.2.

In C2C12 mouse myoblasts ( Figure 4 C), all shuffled variants showed highly significant increased functional transduction over rAAV1 (p < 0.0001), rAAV6 (p < 0.001–0.0001), and rAAV8 (p < 0.01–0.0001).

Analysis of GMFI revealed parallel results, with highly significant MOI effects in MDA-MB-231 (F(2,6) = 427.7, p < 0.0001) and MDA-MB-468 (F(2,6) = 297.6, p < 0.0001), confirming robust dose-dependent increases in bacterial load, whereas MDA-MB-453 exhibited negligible changes.