The LMM over HbO revealed both a highly significant main effect of Condition ( F (2, 437) = 8.59, η p 2 = 0.04, p = 0.0002), indicating that overall activations differed across Speech, Song and Hummed melody, as well as a significant Condition × Trial interaction ( F (2, 438) = 4.61, η p 2 = 0.02, p = 0.0104) (Fig. 4 ), indicating different trends between conditions across the time course of the experiment.
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For example, MNU produced a highly significant ( p < 0.0002) increase in nuclei of > 90.1 μm 2 from 19 to 38%.
However, lower pressure still resulted in highly significant release of the REMIS markers from the brain ( Fig. 2e , left-most panel, P = 0.0002, n = 7, ratio-paired t test).
Results from the ANOVA comparing temporal bisection d-prime confirmed a general impairment in perceptual timing ability in SZ, such that patients showed a highly significant reduction in temporal discrimination sensitivity [F (1,58) = 15.384; p = 0.0002]. 3.2.2 Temporal production Results from the ANOVA comparing SZ and HC mean press rates as a function of time-bins showed significant main effects of group [F (1,58) = 6.13; p = 0.016] and time-bin [F (1,6) = 14.68; p < 0.001], and a significant interaction between the two [F (6,348) = 3.53; p = 0.002].
However, at higher HA wt% (50 and 75), there was a large, highly significant increase in compressive modulus (13.7 and 33.6 MPa, respectively, P < 0.0002 for both).
Association between development of disease and having ⩽50% of lymphocytes of resistant strain origin, and resisting disease and having >50% of lymphocytes of resistant strain origin, was highly significant ( P = 0.0002 by Fisher's Exact Test).
When the FT-T2D was used, 16 of 55 patients (25%; 95% CI 15–39) had score of at least 0.60, the cutoff chosen for eF, which decreased to 12 patients (22%; 95% CI 12–35) without significant fibrosis (FT-T2D < 0.60, Figure 1 C), a highly significant decrease (Nam RMLE-Score = 14.3; p = 0.0002).
We found a modest but highly significant increase in Sgg::YFP levels at stimulated NMJs (12.4 ± 0.02%; P = 0.0002, Student’s t test; Fig. 8, I–K ).
Both the power law and the exponential models fitted well, with high R 2 values (0.999077 and 0.99942, respectively) and being highly significant ( p < .0002).
There was highly significant difference on RI value at day 14 in dogs graded on day 1 of the trial as nonambulatory paraparetic versus paraplegic ( P = .0002), but treatment group remained not significant because of equal distribution of these grades between groups ( P = .73). 3.2.
The degree of the functional overlap across the six BR-signatures is highly significant (P = 0.0002) under a bootstrapped null distribution.
To reduce the bias of time to HSCT2 we analyzed only patients having HSCT2 within 6 months of relapse and found that having HSCT2 was a highly significant predictive factor in this univariate analysis ( P =0.0002).
Therefore this is the only group with a highly significant attentional modulation of interpeak distance ( p = 0.0002, two-tailed t test).
The analysis showed that the level of TMEM244 expression is negatively correlated with the square of the methylation level in the promoter region ( R = −0.4766), and this correlation is highly significant ( P < 0.0002) (Figure 4 ). 4 DISCUSSION In this study, we showed that methylation is a key regulatory mechanism of TMEM244 expression.
The PRC diagram (highly significant, pseudoF = 52.3, p = 0.0002, Fig. 5 ) clearly demonstrated the responses to experimental manipulations.
A pairwise combined microCT and gas exchange analysis of the four Arabidopsis lines revealed a highly significant positive correlation of g s and palisade porosity (Pearson correlation, r 2 = 0.471, P = 0.0002; Fig. 5l ), with the focl-1 mutant data grouping below those for the Col-0 control and on a par with the EPF2OE samples.
This meta-analysis failed to show any benefits of adjuvant bisphosphonates in premenopausal women, but highly significant improvements in bone recurrence (RR = 0.72; 95% CI 0.60–0.86, 2 p = 0.0002) and breast cancer mortality (RR = 0.82; 95% CI 0.73–0.93, 2 p = 0.002) were seen in the 11,767 postmenopausal women included in the meta-analysis.
An unexpected finding is that gender also had a highly significant effect ( F = 14.66, p = 0.0002).
Although observing two siRNA sharing a hexamer seed sequence is not significant at the 5% level, observing two or more such seeds is significant (P = 0.013), while finding four siRNAs sharing a seed sequence is highly significant (P < 0.0002).
Both regressions were highly significant ( p -value = 0.0002 for seed viability and <0.0001 for seed counts).
For α-glucosidase IC 50 , the main regression effect was highly significant (p = 0.0002), indicating a strong relationship between the independent variables (EO proportions) and the response.
The second strongest signal identified in the GWAS, observed at rs12506228, showed two independent replications and the meta-analysis for replication studies was highly significant ( p = 2.0 × 10E-4).
At the same time, 4 patients encountered graft-rejection, and 7 patients died of HSCT-related complications, indicating a highly significant impact of HSCT on the survival rate of patients with actinopathies ( p = 0.0002, Figure 3 ).
A highly significant interaction emerged with factors WordType, PeriExtra, TempFront and Areas ( F 2, 22 = 14.012, p < 0.0002), revealing different CA circuits across the 12 area network between object- and action-related words.
The total signs in February 2020 was 6.2% (10/162) and the total signs in the control group over all months was 1.4% (12/837), which is highly significant ( p =0.0002).